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The map label for this gene is ybfF [C]

Identifier: 154245412

GI number: 154245412

Start: 1675991

End: 1676881

Strand: Direct

Name: ybfF [C]

Synonym: Xaut_1465

Alternate gene names: 154245412

Gene position: 1675991-1676881 (Clockwise)

Preceding gene: 154245408

Following gene: 154245413

Centisome position: 31.57

GC content: 68.91

Gene sequence:

>891_bases
ATGCCTGACACCGCCACGACCGGCGCCGCGCCCGCGCAGGTGGTTCCCTTCCCCGCGGATTTCCGCACCCGGGAGATCGA
AACCAACGGCACGACCATCCATGTCCGCTTCGGCGGCAGCGGGCCGGTGGTCGTCCTGCTGCATGGCTATGGCGAAACCG
GCGACATGTGGGCGCCGATGGCGGCCGCGCTGGCGCCGGACCATACCGTGGTGGTGCCGGACCTGAGGGGCATGGGGCTT
TCCGCAAAGCCGGATGGCGGCTTCGACAAGAAGACCCAGGCCGGCGATGTCGCCGGCGTGCTGGACGCGCTGGGCATCGA
CAAGGCTGCCCTCGTCACCCACGACATCGGCAACATGGTGGGCTTCGCCTTCGCCGCCCTCCATCGCGAGCGGGTGACGC
GGTTCGTCCTCATCGACGCGCCGTTGCCGGGCGTGGGGCCGTGGGAGGAGATCCTCAAGAATCCGCTGCTCTGGCATTTC
CGCTTCGGCGGCCCGGACATGGAGCGGCTGGTGGAGGGGCGCGAGCGTATCTACCTCGATCGCTTCTGGAACGAATTCTC
CGCCCATCCCAGCCATTTCGGCGAGGCGGCGCGGGCGCACTACGCCGCGCTCTATGCCCTGCCGGGCGCCATGCGGGCGG
GCTTCGCCCAGTTCGCCGCCTTCGACCAGGATGCCATCGACAACAAGGCTTTCCTCGCCGCCGGCAAGCTCACGGTGCCG
GTGCTGGCGCTGGGCGGCGAAATGTCGTTCGGCCTGACCATGGCGGAGGTGATGAAATTCGCCGCCACGGACGTGAAAGG
CGACATCGTCCCCGGCAGCGGGCACTGGATCATGGAGGAGAACCCGGCCGCGACCGTGGCGCTGGTCAAGGCCTTCCTCG
CCGCCGGATGA

Upstream 100 bases:

>100_bases
CGCGGAGAAATCGACCCCGCCACACTACTGCGCTCGGCCTTATGGCGCCATACTCCTGCGGCCGCGCACGCACCGGGGGT
GCCGCGATGGAGGACGTCCC

Downstream 100 bases:

>100_bases
TCTGCCGGCCACAAGCGGGCGGGTGGACCGGCGCCGGCCGCATTCCCGGCGCGCGCGAAGCTGTGCTAGACCTGCCTTCC
GACAGGAGGACCCCATGCCC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: SEH; Cytosolic epoxide hydrolase; cEH; Epoxide hydratase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPDTATTGAAPAQVVPFPADFRTREIETNGTTIHVRFGGSGPVVVLLHGYGETGDMWAPMAAALAPDHTVVVPDLRGMGL
SAKPDGGFDKKTQAGDVAGVLDALGIDKAALVTHDIGNMVGFAFAALHRERVTRFVLIDAPLPGVGPWEEILKNPLLWHF
RFGGPDMERLVEGRERIYLDRFWNEFSAHPSHFGEAARAHYAALYALPGAMRAGFAQFAAFDQDAIDNKAFLAAGKLTVP
VLALGGEMSFGLTMAEVMKFAATDVKGDIVPGSGHWIMEENPAATVALVKAFLAAG

Sequences:

>Translated_296_residues
MPDTATTGAAPAQVVPFPADFRTREIETNGTTIHVRFGGSGPVVVLLHGYGETGDMWAPMAAALAPDHTVVVPDLRGMGL
SAKPDGGFDKKTQAGDVAGVLDALGIDKAALVTHDIGNMVGFAFAALHRERVTRFVLIDAPLPGVGPWEEILKNPLLWHF
RFGGPDMERLVEGRERIYLDRFWNEFSAHPSHFGEAARAHYAALYALPGAMRAGFAQFAAFDQDAIDNKAFLAAGKLTVP
VLALGGEMSFGLTMAEVMKFAATDVKGDIVPGSGHWIMEENPAATVALVKAFLAAG
>Mature_295_residues
PDTATTGAAPAQVVPFPADFRTREIETNGTTIHVRFGGSGPVVVLLHGYGETGDMWAPMAAALAPDHTVVVPDLRGMGLS
AKPDGGFDKKTQAGDVAGVLDALGIDKAALVTHDIGNMVGFAFAALHRERVTRFVLIDAPLPGVGPWEEILKNPLLWHFR
FGGPDMERLVEGRERIYLDRFWNEFSAHPSHFGEAARAHYAALYALPGAMRAGFAQFAAFDQDAIDNKAFLAAGKLTVPV
LALGGEMSFGLTMAEVMKFAATDVKGDIVPGSGHWIMEENPAATVALVKAFLAAG

Specific function: Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17554012, Length=288, Percent_Identity=23.2638888888889, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR010497 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF06441 EHN [H]

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 31479; Mature: 31348

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTATTGAAPAQVVPFPADFRTREIETNGTTIHVRFGGSGPVVVLLHGYGETGDMWAPM
CCCCCCCCCCCCEEECCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCCHHHH
AAALAPDHTVVVPDLRGMGLSAKPDGGFDKKTQAGDVAGVLDALGIDKAALVTHDIGNMV
HHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
GFAFAALHRERVTRFVLIDAPLPGVGPWEEILKNPLLWHFRFGGPDMERLVEGRERIYLD
HHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
RFWNEFSAHPSHFGEAARAHYAALYALPGAMRAGFAQFAAFDQDAIDNKAFLAAGKLTVP
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCEEEEECCCEEE
VLALGGEMSFGLTMAEVMKFAATDVKGDIVPGSGHWIMEENPAATVALVKAFLAAG
EEEECCCCCCCHHHHHHHHHHHCCCCCCEECCCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PDTATTGAAPAQVVPFPADFRTREIETNGTTIHVRFGGSGPVVVLLHGYGETGDMWAPM
CCCCCCCCCCCEEECCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCCHHHH
AAALAPDHTVVVPDLRGMGLSAKPDGGFDKKTQAGDVAGVLDALGIDKAALVTHDIGNMV
HHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
GFAFAALHRERVTRFVLIDAPLPGVGPWEEILKNPLLWHFRFGGPDMERLVEGRERIYLD
HHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
RFWNEFSAHPSHFGEAARAHYAALYALPGAMRAGFAQFAAFDQDAIDNKAFLAAGKLTVP
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCEEEEECCCEEE
VLALGGEMSFGLTMAEVMKFAATDVKGDIVPGSGHWIMEENPAATVALVKAFLAAG
EEEECCCCCCCHHHHHHHHHHHCCCCCCEECCCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9578475 [H]