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The map label for this gene is ffh [H]

Identifier: 154245411

GI number: 154245411

Start: 1674086

End: 1675627

Strand: Reverse

Name: ffh [H]

Synonym: Xaut_1464

Alternate gene names: 154245411

Gene position: 1675627-1674086 (Counterclockwise)

Preceding gene: 154245415

Following gene: 154245410

Centisome position: 31.56

GC content: 69.91

Gene sequence:

>1542_bases
ATGTTCGATACCCTTTCCGACCGCCTCGGCGGCATACTCGACAAGCTGAAGCGGCGCGGCGCCCTCACCGAGGCCGACGT
GGGCGAGGCCATGCGCGAGGTGCGCCGCGCGCTGATCGAGGCGGACGTGGCCCTCGACGTGGTGCGCTCCTTCACCGACC
GGGTGAAGAATCGCGCCGTGGGCGTGGAGGTCATCAAGTCGGTGACCCCCGGGCAGATGGTGGTCAAGATCGTTCATGAC
GAGCTTGTCGCCACCCTGGGCTCCGACGCCGATCCCATCGATCTCAACGCCCCCGCCCCCGTCCCCATCCTGATGGTGGG
CCTGCAGGGCTCGGGCAAGACCACCTCGACGGCCAAGATCGCCAAGCGCCTCACCGAACGCGGCAAGCGCAAGGTGCTGA
TGGCGTCCCTCGACACCCGCCGTCCCGCCGCCATGGAGCAGCTGGCCACCCTCGGCAAGCAGGTGGAGGTGGCGACCCTG
CCCATCGTCGCCGGCCAGAGCGCGGTGCAGATCGCGAAGCGCGCCATCGAGGCGGCGAAGCTCGGTGGCTACGACGTGGT
CATGCTCGACACCGCCGGCCGCGTGACGCTGGACGAGGCCCTCATGGCCGAGGTGGCCGAGGTGAAGGCCGCCACCGGCC
CGCACGAAGTGCTGCTGGTGGCTGACAGCCTCACCGGCCAGGACGCGGTGAACACCGCCAAGGCGTTCGACGGCCGGGTC
GGCCTCACCGGCATCGTGCTCACCCGCGCCGACGGCGATGGCCGCGGCGGCGCGGCGCTGTCCATGCGCGCGGTCACCGG
CAAGCCCATCAAGCTGCTCGGCACCGGCGAGAAGATGGACGCGCTGGAGGATTTCGATCCCCATCGCGTGGCCGGCCGCA
TCCTCGGCATGGGCGACGTGGTGGCGCTGGTGGAGAAGGCCGCCGAGGCCATCGACATCGAGAAGGCGAAGGTCACCGCC
GAGCGCATGCGCAAGGGCACCTTCGACCTGGACGACCTGCGCAGCCAGCTGGAGCAGATGGCGAAGATGGGCGGGCTCGG
TGGGCTCATGGGCATGCTGCCCGGCGTCGCCAAGATGAAGAACCAGATCGCCTCCGCCAATCTCGACGACAAGGTGTTCA
AGCGGCAGGTGGCCATCATCAATTCGATGACGCCGAAGGAGCGCCGCGCCCCCAAGCTCCTCGACGCCTCGCGCAAGCGC
CGCATCGCCGCCGGCTCCGGCACCAAGGTGGAGGAGATCAACCGTCTCCTGAAGATGCACCGCCAGATGGCCGACGTGAT
GAAGTCGCTGGGCGGCGCCGCCGGCAAGCGCGGCCCGCTGGCGGGCCTTGCCGGCATGATGGGCTTCGGCGGCGGCGGAC
CGTCCCCCGAGATGCTCAAGGACATGGCCGAGAAGATGGGCGCCGGTGGTCCCGGTGGCGCGGGCGGGTTGCCCCCCAAC
TTCCCCGGCCTGCCGGGTGGCGGACTGCCGCCCAAGTTCCCCGGCGGCCTGCCGGGCCTGCCGAAAGGCCTTCCTGGACT
GGGAGGCTTGAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
CCTCGGGCGCGATCTGCGTTGTCTTGAGGCGTAGCCGTCTCGACACGGGCGCGGGGCCGGCTCCGGCCCGTCTTATGTGA
AACCCAAACCACGGACGGCC

Downstream 100 bases:

>100_bases
CGCGGATTCCAGCTCTCCGTCATGGCCGGGCAGCACGATCCCGACCAGCACGATCACTCATCGAACGACCAAAGGAAGAA
ACCCATGTCCCTGAAGATCC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MFDTLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDRVKNRAVGVEVIKSVTPGQMVVKIVHD
ELVATLGSDADPIDLNAPAPVPILMVGLQGSGKTTSTAKIAKRLTERGKRKVLMASLDTRRPAAMEQLATLGKQVEVATL
PIVAGQSAVQIAKRAIEAAKLGGYDVVMLDTAGRVTLDEALMAEVAEVKAATGPHEVLLVADSLTGQDAVNTAKAFDGRV
GLTGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDALEDFDPHRVAGRILGMGDVVALVEKAAEAIDIEKAKVTA
ERMRKGTFDLDDLRSQLEQMAKMGGLGGLMGMLPGVAKMKNQIASANLDDKVFKRQVAIINSMTPKERRAPKLLDASRKR
RIAAGSGTKVEEINRLLKMHRQMADVMKSLGGAAGKRGPLAGLAGMMGFGGGGPSPEMLKDMAEKMGAGGPGGAGGLPPN
FPGLPGGGLPPKFPGGLPGLPKGLPGLGGLKKK

Sequences:

>Translated_513_residues
MFDTLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDRVKNRAVGVEVIKSVTPGQMVVKIVHD
ELVATLGSDADPIDLNAPAPVPILMVGLQGSGKTTSTAKIAKRLTERGKRKVLMASLDTRRPAAMEQLATLGKQVEVATL
PIVAGQSAVQIAKRAIEAAKLGGYDVVMLDTAGRVTLDEALMAEVAEVKAATGPHEVLLVADSLTGQDAVNTAKAFDGRV
GLTGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDALEDFDPHRVAGRILGMGDVVALVEKAAEAIDIEKAKVTA
ERMRKGTFDLDDLRSQLEQMAKMGGLGGLMGMLPGVAKMKNQIASANLDDKVFKRQVAIINSMTPKERRAPKLLDASRKR
RIAAGSGTKVEEINRLLKMHRQMADVMKSLGGAAGKRGPLAGLAGMMGFGGGGPSPEMLKDMAEKMGAGGPGGAGGLPPN
FPGLPGGGLPPKFPGGLPGLPKGLPGLGGLKKK
>Mature_513_residues
MFDTLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDRVKNRAVGVEVIKSVTPGQMVVKIVHD
ELVATLGSDADPIDLNAPAPVPILMVGLQGSGKTTSTAKIAKRLTERGKRKVLMASLDTRRPAAMEQLATLGKQVEVATL
PIVAGQSAVQIAKRAIEAAKLGGYDVVMLDTAGRVTLDEALMAEVAEVKAATGPHEVLLVADSLTGQDAVNTAKAFDGRV
GLTGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDALEDFDPHRVAGRILGMGDVVALVEKAAEAIDIEKAKVTA
ERMRKGTFDLDDLRSQLEQMAKMGGLGGLMGMLPGVAKMKNQIASANLDDKVFKRQVAIINSMTPKERRAPKLLDASRKR
RIAAGSGTKVEEINRLLKMHRQMADVMKSLGGAAGKRGPLAGLAGMMGFGGGGPSPEMLKDMAEKMGAGGPGGAGGLPPN
FPGLPGGGLPPKFPGGLPGLPKGLPGLGGLKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=447, Percent_Identity=29.9776286353468, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI226371618, Length=397, Percent_Identity=30.2267002518892, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI23308697, Length=316, Percent_Identity=29.746835443038, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI295424842, Length=316, Percent_Identity=29.746835443038, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI89061728, Length=158, Percent_Identity=32.9113924050633, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=54.0094339622642, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1789874, Length=215, Percent_Identity=37.6744186046512, Blast_Score=136, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=431, Percent_Identity=31.0904872389791, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI193206261, Length=215, Percent_Identity=34.4186046511628, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325345, Length=488, Percent_Identity=31.7622950819672, Blast_Score=217, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6320498, Length=315, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17647949, Length=434, Percent_Identity=28.5714285714286, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24641198, Length=303, Percent_Identity=30.03300330033, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53445; Mature: 53445

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDRVKNRAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVEVIKSVTPGQMVVKIVHDELVATLGSDADPIDLNAPAPVPILMVGLQGSGKTTSTAKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
AKRLTERGKRKVLMASLDTRRPAAMEQLATLGKQVEVATLPIVAGQSAVQIAKRAIEAAK
HHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHCCCEEEEEECEECCHHHHHHHHHHHHHHH
LGGYDVVMLDTAGRVTLDEALMAEVAEVKAATGPHEVLLVADSLTGQDAVNTAKAFDGRV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
GLTGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDALEDFDPHRVAGRILGMGDV
CCEEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHCCCHHHHHHHHHCHHHH
VALVEKAAEAIDIEKAKVTAERMRKGTFDLDDLRSQLEQMAKMGGLGGLMGMLPGVAKMK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHH
NQIASANLDDKVFKRQVAIINSMTPKERRAPKLLDASRKRRIAAGSGTKVEEINRLLKMH
HHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHH
RQMADVMKSLGGAAGKRGPLAGLAGMMGFGGGGPSPEMLKDMAEKMGAGGPGGAGGLPPN
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
FPGLPGGGLPPKFPGGLPGLPKGLPGLGGLKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDTLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDRVKNRAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVEVIKSVTPGQMVVKIVHDELVATLGSDADPIDLNAPAPVPILMVGLQGSGKTTSTAKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
AKRLTERGKRKVLMASLDTRRPAAMEQLATLGKQVEVATLPIVAGQSAVQIAKRAIEAAK
HHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHCCCEEEEEECEECCHHHHHHHHHHHHHHH
LGGYDVVMLDTAGRVTLDEALMAEVAEVKAATGPHEVLLVADSLTGQDAVNTAKAFDGRV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
GLTGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDALEDFDPHRVAGRILGMGDV
CCEEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHCCCHHHHHHHHHCHHHH
VALVEKAAEAIDIEKAKVTAERMRKGTFDLDDLRSQLEQMAKMGGLGGLMGMLPGVAKMK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHH
NQIASANLDDKVFKRQVAIINSMTPKERRAPKLLDASRKRRIAAGSGTKVEEINRLLKMH
HHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHH
RQMADVMKSLGGAAGKRGPLAGLAGMMGFGGGGPSPEMLKDMAEKMGAGGPGGAGGLPPN
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
FPGLPGGGLPPKFPGGLPGLPKGLPGLGGLKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]