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The map label for this gene is xseA

Identifier: 154245360

GI number: 154245360

Start: 1616675

End: 1618165

Strand: Direct

Name: xseA

Synonym: Xaut_1413

Alternate gene names: 154245360

Gene position: 1616675-1618165 (Clockwise)

Preceding gene: 154245355

Following gene: 154245361

Centisome position: 30.45

GC content: 72.7

Gene sequence:

>1491_bases
ATGCTAATTTCTGAACCAACAGCCGACTGCGATTCGATGGTGGATGTCGCCGAACCCCGCGCCAACGCGCCAGAATGGAG
CGTTTCCGAGCTCTCTGCCGCGCTCCGGCGCACGGTTGAGGACGCCTACGGCCACGTGCGGGTGCGCGGCGAAATCTCCG
GCTATCGCGGGCCGCATGGCTCGGGCCACGCCTATTTCAGCCTGAAGGATGCCGGCGCGCGGCTCGACGCGGTGATCTGG
AAGGGCACCTTCCAGCGCCTGCGCCTGAAGCCCGAGGAGGGGTTGGAGGTTGTGGCCATCGGCCGCCTCACCACCTATCC
GGGCAAGTCGGGCTACCAGATCGTCATCGAGGCGCTGGAATTCGCCGGCGCGGGCGCCATCATGGCCATGCTGGAGGAGC
GCAAGCGCCGCCTCTCCGCCGAGGGCCTGTTCGATCCGGCGCGCAAGGTCGCGCTGCCGTTCCTGCCGCAGGTGATCGGG
GTGGTCACCTCGCCCACCGGGGCGGTGATCCGCGACATCCTCCACCGCCTCGACGACCGGTTTCCGCGCCGGGTGCTGGT
GTGGCCGGTGCGGGTGCAGGGCGAGACCTCGGCTGCGGAGGTGGCGGCGGCCATTCGCGGCTTCAACGCCTTGCCGGCGG
GCGGCGCCATCCCGCGTCCCGACGTGATCGTGGTGGCGCGGGGCGGCGGCGCGCTGGAGGACCTTCTGGGCTTCTCCGAC
GAGGAGGTGGTGCGGGCGGCGGCGGAAAGCGCCATCCCGCTGGTTGCCGCCGTGGGCCACGAGACCGACGTCACCCTCAT
CGATTTCGCCGCCGACGTGCGGGCGCCCACCCCTACCGCCGCCGCCGAGATGGTGGTGCCGGTGCGTTCCGAGCTGATTG
CGGCGGTGGAAGACCTGGGCGGGCGCCTCGCTGCCGCCCCGGTGCGGCTTCTGGAGCGGCGGCGGGCGGACCTGCGCGGC
CTGTCGCGGCTCCTGCCCAGCGCGGAGAACCTGCTTTCGGTGCCCCGGCAGCGGCTCGATGCCGCGAGCGAGCGCCTGCC
GCGGGCGCTCAAGGCCAATGCCGCCGCCCACCGCCTGCGCCTCGTGGCCGCGCGGGCCCGGCTGTCCCCGGAGGCGCTGA
GGCTGCGCCTGGAGCGCGCCGGCGACCGGCTGGAGACGCTGGACGGCCGCCTGAAACGCGCCTTTTCGGTCGCGCGCGAG
CAGCGGGCAGCGCGGCTGAGATCGGCGGGGCAACTGCTGGATGCCCTGTCCTTCAAGGGGGTGCTGAGCCGTGGCTTCGC
GCTGGTGCGCGATGCGCAGGGCCAGCCGGTGCGCCTTGCCGCTGGCCTCACGGCGGGCACGGCGCTGGATCTTGAGTTCG
CAGACGGGCATGTGGCGGCGGTAACGGGGGATGTGGTGCCGGCTGCCACGCCTGCTGCGCCCGCGCGGCCACGCCCGGCG
AAATCCAGGAAGCCGCCCAAGGTCGAGGGGCCGACCCTGTTCGATCGGTGA

Upstream 100 bases:

>100_bases
CGTCTCTTGCGAGAGTCTCTTGTCACAATCGCCTATCGGCTCAGGGCCGCGCAAACAAGAGGCACGGCTCTGCGCTCGCC
GCATGGGGGGCTTTCCCGCT

Downstream 100 bases:

>100_bases
GCCGGCGCCTCTTTCGCGCTGCGGGGCGAATGGCTATGCTGGAAATTCTTCTTTCAGGACGATAACGGCTGTGATGAACA
GATTCGAACGCTTTCCCGAG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MLISEPTADCDSMVDVAEPRANAPEWSVSELSAALRRTVEDAYGHVRVRGEISGYRGPHGSGHAYFSLKDAGARLDAVIW
KGTFQRLRLKPEEGLEVVAIGRLTTYPGKSGYQIVIEALEFAGAGAIMAMLEERKRRLSAEGLFDPARKVALPFLPQVIG
VVTSPTGAVIRDILHRLDDRFPRRVLVWPVRVQGETSAAEVAAAIRGFNALPAGGAIPRPDVIVVARGGGALEDLLGFSD
EEVVRAAAESAIPLVAAVGHETDVTLIDFAADVRAPTPTAAAEMVVPVRSELIAAVEDLGGRLAAAPVRLLERRRADLRG
LSRLLPSAENLLSVPRQRLDAASERLPRALKANAAAHRLRLVAARARLSPEALRLRLERAGDRLETLDGRLKRAFSVARE
QRAARLRSAGQLLDALSFKGVLSRGFALVRDAQGQPVRLAAGLTAGTALDLEFADGHVAAVTGDVVPAATPAAPARPRPA
KSRKPPKVEGPTLFDR

Sequences:

>Translated_496_residues
MLISEPTADCDSMVDVAEPRANAPEWSVSELSAALRRTVEDAYGHVRVRGEISGYRGPHGSGHAYFSLKDAGARLDAVIW
KGTFQRLRLKPEEGLEVVAIGRLTTYPGKSGYQIVIEALEFAGAGAIMAMLEERKRRLSAEGLFDPARKVALPFLPQVIG
VVTSPTGAVIRDILHRLDDRFPRRVLVWPVRVQGETSAAEVAAAIRGFNALPAGGAIPRPDVIVVARGGGALEDLLGFSD
EEVVRAAAESAIPLVAAVGHETDVTLIDFAADVRAPTPTAAAEMVVPVRSELIAAVEDLGGRLAAAPVRLLERRRADLRG
LSRLLPSAENLLSVPRQRLDAASERLPRALKANAAAHRLRLVAARARLSPEALRLRLERAGDRLETLDGRLKRAFSVARE
QRAARLRSAGQLLDALSFKGVLSRGFALVRDAQGQPVRLAAGLTAGTALDLEFADGHVAAVTGDVVPAATPAAPARPRPA
KSRKPPKVEGPTLFDR
>Mature_496_residues
MLISEPTADCDSMVDVAEPRANAPEWSVSELSAALRRTVEDAYGHVRVRGEISGYRGPHGSGHAYFSLKDAGARLDAVIW
KGTFQRLRLKPEEGLEVVAIGRLTTYPGKSGYQIVIEALEFAGAGAIMAMLEERKRRLSAEGLFDPARKVALPFLPQVIG
VVTSPTGAVIRDILHRLDDRFPRRVLVWPVRVQGETSAAEVAAAIRGFNALPAGGAIPRPDVIVVARGGGALEDLLGFSD
EEVVRAAAESAIPLVAAVGHETDVTLIDFAADVRAPTPTAAAEMVVPVRSELIAAVEDLGGRLAAAPVRLLERRRADLRG
LSRLLPSAENLLSVPRQRLDAASERLPRALKANAAAHRLRLVAARARLSPEALRLRLERAGDRLETLDGRLKRAFSVARE
QRAARLRSAGQLLDALSFKGVLSRGFALVRDAQGQPVRLAAGLTAGTALDLEFADGHVAAVTGDVVPAATPAAPARPRPA
KSRKPPKVEGPTLFDR

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=445, Percent_Identity=33.9325842696629, Blast_Score=239, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 52966; Mature: 52966

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISEPTADCDSMVDVAEPRANAPEWSVSELSAALRRTVEDAYGHVRVRGEISGYRGPHG
CCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
SGHAYFSLKDAGARLDAVIWKGTFQRLRLKPEEGLEVVAIGRLTTYPGKSGYQIVIEALE
CCEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEECEECCCCCCCHHHHHHHHH
FAGAGAIMAMLEERKRRLSAEGLFDPARKVALPFLPQVIGVVTSPTGAVIRDILHRLDDR
HCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FPRRVLVWPVRVQGETSAAEVAAAIRGFNALPAGGAIPRPDVIVVARGGGALEDLLGFSD
CCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCH
EEVVRAAAESAIPLVAAVGHETDVTLIDFAADVRAPTPTAAAEMVVPVRSELIAAVEDLG
HHHHHHHHHHCCCEEEECCCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GRLAAAPVRLLERRRADLRGLSRLLPSAENLLSVPRQRLDAASERLPRALKANAAAHRLR
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVAARARLSPEALRLRLERAGDRLETLDGRLKRAFSVAREQRAARLRSAGQLLDALSFKG
HHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSRGFALVRDAQGQPVRLAAGLTAGTALDLEFADGHVAAVTGDVVPAATPAAPARPRPA
HHHHCHHEEECCCCCCEEEEECCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
KSRKPPKVEGPTLFDR
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLISEPTADCDSMVDVAEPRANAPEWSVSELSAALRRTVEDAYGHVRVRGEISGYRGPHG
CCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
SGHAYFSLKDAGARLDAVIWKGTFQRLRLKPEEGLEVVAIGRLTTYPGKSGYQIVIEALE
CCEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEECEECCCCCCCHHHHHHHHH
FAGAGAIMAMLEERKRRLSAEGLFDPARKVALPFLPQVIGVVTSPTGAVIRDILHRLDDR
HCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FPRRVLVWPVRVQGETSAAEVAAAIRGFNALPAGGAIPRPDVIVVARGGGALEDLLGFSD
CCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCH
EEVVRAAAESAIPLVAAVGHETDVTLIDFAADVRAPTPTAAAEMVVPVRSELIAAVEDLG
HHHHHHHHHHCCCEEEECCCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GRLAAAPVRLLERRRADLRGLSRLLPSAENLLSVPRQRLDAASERLPRALKANAAAHRLR
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVAARARLSPEALRLRLERAGDRLETLDGRLKRAFSVAREQRAARLRSAGQLLDALSFKG
HHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSRGFALVRDAQGQPVRLAAGLTAGTALDLEFADGHVAAVTGDVVPAATPAAPARPRPA
HHHHCHHEEECCCCCCEEEEECCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
KSRKPPKVEGPTLFDR
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA