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The map label for this gene is cphA [H]

Identifier: 154245248

GI number: 154245248

Start: 1496650

End: 1497444

Strand: Reverse

Name: cphA [H]

Synonym: Xaut_1300

Alternate gene names: 154245248

Gene position: 1497444-1496650 (Counterclockwise)

Preceding gene: 154245250

Following gene: 154245247

Centisome position: 28.21

GC content: 70.19

Gene sequence:

>795_bases
GTGAGCACCGCGACCGCACCCGCCGCCAAGAAATTCGCAAGCCAGGCCGATCTCGCCGAGAAGAAGGAAACCTTCACCGA
GCTTGCGGACGGCGTCTTCGCCCTCACCGCGGAGGGCGATCCCAATTCCGGCGTCATCATCGGCGACGACAGCGTGCTGG
TCGTCGACGCCCGCGCCACCCCGGTCATGGCGCGCGAGCTGGTGGAGCGCATCCGCGCCGTCACCGACAAGCCCATCCGC
CACGTGCTGCTCACCCATTATCACGCGGTGCGGGTGCTGGGCGCGGCCGGCTTCGACGAGCGCGTCAACGTCATCGCCTC
CGACGTCACCCGCGACATGATCGTGGAGCGCGGCGCGCAGGACATGGCCTCCGAGATCCAGCGCTTCCCGCGCCTGTTCC
GGGCGCAGGAGACCATTCCCGGCCTCACCTGGCCCAGCCTCACCTTCCACGGCGAGATGACGCTCTGGCTCGGCTCCCGC
GAAGTCCGCATCATCCATGCCGGGCGCGGTCACACACGCGGCGACACCATCGCCTGGCTGCCGAAGGAGAAGGTGCTGTT
CGCCGGCGACCTGGTGGAGTATGGCGCCACGCCCTATTGCGGCGATGCCCATTTCCGCGACTGGCCCGCGACCCTCGACC
GGCTGGAGGCGCTGGGCGCGGAAAAGCTGGTGCCGGGCCGCGGCGAGGCGCTCACCACCCCCGGCCAGATCAAGGCCGGG
CTGGACGAGACCCGCGCCTTCCTGCGCGACGCCTTCGCCATCGCCGAGGCGGGCGTAAGGCGGGGCATGACCTGA

Upstream 100 bases:

>100_bases
TCAAACTGTCGAAGAACAAGGAAGCGCGCATCGGACGACCGGCGGCCATCGACGCCGGAAGCCAGCACTCCTGCGCCGCG
CACCAACGGAGGAAACCCGC

Downstream 100 bases:

>100_bases
AGACGGTCTATGCCGAGGCGCTGCGGCAGATGCGGCCCAAGTATGGGCATTGGGTCATCTTCGACCATTGCATGCCGTTC
GATATCTCCCGCGCCTATGA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSTATAPAAKKFASQADLAEKKETFTELADGVFALTAEGDPNSGVIIGDDSVLVVDARATPVMARELVERIRAVTDKPIR
HVLLTHYHAVRVLGAAGFDERVNVIASDVTRDMIVERGAQDMASEIQRFPRLFRAQETIPGLTWPSLTFHGEMTLWLGSR
EVRIIHAGRGHTRGDTIAWLPKEKVLFAGDLVEYGATPYCGDAHFRDWPATLDRLEALGAEKLVPGRGEALTTPGQIKAG
LDETRAFLRDAFAIAEAGVRRGMT

Sequences:

>Translated_264_residues
MSTATAPAAKKFASQADLAEKKETFTELADGVFALTAEGDPNSGVIIGDDSVLVVDARATPVMARELVERIRAVTDKPIR
HVLLTHYHAVRVLGAAGFDERVNVIASDVTRDMIVERGAQDMASEIQRFPRLFRAQETIPGLTWPSLTFHGEMTLWLGSR
EVRIIHAGRGHTRGDTIAWLPKEKVLFAGDLVEYGATPYCGDAHFRDWPATLDRLEALGAEKLVPGRGEALTTPGQIKAG
LDETRAFLRDAFAIAEAGVRRGMT
>Mature_263_residues
STATAPAAKKFASQADLAEKKETFTELADGVFALTAEGDPNSGVIIGDDSVLVVDARATPVMARELVERIRAVTDKPIRH
VLLTHYHAVRVLGAAGFDERVNVIASDVTRDMIVERGAQDMASEIQRFPRLFRAQETIPGLTWPSLTFHGEMTLWLGSRE
VRIIHAGRGHTRGDTIAWLPKEKVLFAGDLVEYGATPYCGDAHFRDWPATLDRLEALGAEKLVPGRGEALTTPGQIKAGL
DETRAFLRDAFAIAEAGVRRGMT

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 28774; Mature: 28643

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATAPAAKKFASQADLAEKKETFTELADGVFALTAEGDPNSGVIIGDDSVLVVDARAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEECCCCEEEEECCCC
PVMARELVERIRAVTDKPIRHVLLTHYHAVRVLGAAGFDERVNVIASDVTRDMIVERGAQ
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHH
DMASEIQRFPRLFRAQETIPGLTWPSLTFHGEMTLWLGSREVRIIHAGRGHTRGDTIAWL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCEEEEEECCCCCCCCCEEEEC
PKEKVLFAGDLVEYGATPYCGDAHFRDWPATLDRLEALGAEKLVPGRGEALTTPGQIKAG
CCCCEEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCEECCCCHHHCC
LDETRAFLRDAFAIAEAGVRRGMT
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STATAPAAKKFASQADLAEKKETFTELADGVFALTAEGDPNSGVIIGDDSVLVVDARAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEECCCCEEEEECCCC
PVMARELVERIRAVTDKPIRHVLLTHYHAVRVLGAAGFDERVNVIASDVTRDMIVERGAQ
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHH
DMASEIQRFPRLFRAQETIPGLTWPSLTFHGEMTLWLGSREVRIIHAGRGHTRGDTIAWL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCEEEEEECCCCCCCCCEEEEC
PKEKVLFAGDLVEYGATPYCGDAHFRDWPATLDRLEALGAEKLVPGRGEALTTPGQIKAG
CCCCEEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCEECCCCHHHCC
LDETRAFLRDAFAIAEAGVRRGMT
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1856163 [H]