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The map label for this gene is zraR [H]

Identifier: 154245240

GI number: 154245240

Start: 1487586

End: 1488986

Strand: Reverse

Name: zraR [H]

Synonym: Xaut_1292

Alternate gene names: 154245240

Gene position: 1488986-1487586 (Counterclockwise)

Preceding gene: 154245241

Following gene: 154245239

Centisome position: 28.05

GC content: 70.66

Gene sequence:

>1401_bases
ATGGCCACCACCGCCGATGCCCCGCAGGAGGCGCCTCACGCCGCCAGCGACATCGCCTTCAGCCCGCATCTTTCCGGCGC
CTCCATCCTGGTGGTGGACGACGAACCCGGCATGCGGAACTTCCTCGTGCGCATGCTCGCCTCGCGCTGCCGGCACGTGG
CGGAGGCGGCGGACGTGGCGGCGGCCTCGAAGCTGCTGGAGGCGACGCCTTTCGACCTCATCATCCTCGACAACATCATG
GCCGGGCGCACCGGGCTCGAATGGCTGGAGGAGCTGCGCGGCTCGGGCTTCCATCGCGACGTGATCCTCATCACCGCCTT
CGCGGACCTCGAAACCGCCATCAAGGCCCTGCGGGCCGGTGCGGCGGACTTCGTGCTGAAGCCGTTCCGCTCCAACCAGA
TCCTCAACGCCATCGCCCGCTGCCTCGACCGGGGCCGGCTGATGCGCGAGAATTTCGTGCTGCGCCGCGAGTTGAAGGCC
CTGCCCGGCGTCGGCGCCATGGTGGGCGCCTCCAATGCCACCCGCTCGGTGCGGGGCATGATCGAGCGCGTCGGCCCCAT
GCCCACCACCGTGCTGGTCACCGGCGAATCCGGCACCGGCAAGGAGGTCACCGCCCGCTCGCTGCACGATGTCTCGTCCC
GCGCCGGCAAGCCGTTCGTGCCGGTGAACTGCGCCGCCATCGCCCCCGAGATCATCGAAAGCGAGCTGTTCGGCCACCTG
AAGGGCGCCTTCACCGGCGCCGCCTCCTCCCGCGAGGGGCTGTTCTTCTATGCCCAGGGCGGCACGCTGTTCCTCGACGA
GGTGGGCGAGCTGCCCCCCGCCATGCAATCGAAGCTCTTGCGCGTCATCGAGGACAAGAAGGTGCGGCCGGTGGGCGCGG
AGCGGGAGATCCCGGTGGACGTGCGCCTCATCGCCGCCACCAATTGCGATCTCGCCACGGCGGTGGCGCAGGGCCGCTTT
CGGCAGGATCTCTATTACCGGCTCAACGTGGTCAACATCCACCTCGCCCCCCTGCGCGCGCGGGCGGCGGATGTCGAGCC
GCTGGCCCACCTGTTCATGGCCGAGCTGTCGGCCCAATTGGGCGTGCCGCCCCTCGACCTGACGGCGGGGGTGCTGCGCG
CCCTCACCCGCTACGACTGGCCCGGAAACGTGCGCGAGCTGCGCAACGTCATCGAGCGCTCGCTCATCCTCGGCGAATTC
CCGAGCGACGTGGTGCCGGACGCCGACGAGGAACCGGCGGCGGCGGACGTGGACGCCCTGCCGCAGGCCCTCGGCGCGGT
GGAGAAGGCCCACATGCTCAAGGTGCTGGGCGAGGCCGGCGGCAACCGGGCGGAGGCGGCGCGGCGCCTCGGCGTCTCGC
GCAAGACCCTCGACCGCAAGCTGAAGGCCTGGAATGCCTGA

Upstream 100 bases:

>100_bases
CGCGCCAGCGGCGGGCCACACGACGCGTCTTTCGCGAAAGGCCCTCAGCAGGCGCCGGATCGGGTGCCGGCGGGGGTCTC
AGAAGGACGATCGAGACCTG

Downstream 100 bases:

>100_bases
ACCGGCGGCGCAGGCCGCGCCGAGGCATTTGTTCTCCCGCCTGCGCTCGGTGCGGGCGCGGCTGCTGGCCATCGCGCTGT
TGCCGACGCTGATCATCATG

Product: two component sigma54 specific Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MATTADAPQEAPHAASDIAFSPHLSGASILVVDDEPGMRNFLVRMLASRCRHVAEAADVAAASKLLEATPFDLIILDNIM
AGRTGLEWLEELRGSGFHRDVILITAFADLETAIKALRAGAADFVLKPFRSNQILNAIARCLDRGRLMRENFVLRRELKA
LPGVGAMVGASNATRSVRGMIERVGPMPTTVLVTGESGTGKEVTARSLHDVSSRAGKPFVPVNCAAIAPEIIESELFGHL
KGAFTGAASSREGLFFYAQGGTLFLDEVGELPPAMQSKLLRVIEDKKVRPVGAEREIPVDVRLIAATNCDLATAVAQGRF
RQDLYYRLNVVNIHLAPLRARAADVEPLAHLFMAELSAQLGVPPLDLTAGVLRALTRYDWPGNVRELRNVIERSLILGEF
PSDVVPDADEEPAAADVDALPQALGAVEKAHMLKVLGEAGGNRAEAARRLGVSRKTLDRKLKAWNA

Sequences:

>Translated_466_residues
MATTADAPQEAPHAASDIAFSPHLSGASILVVDDEPGMRNFLVRMLASRCRHVAEAADVAAASKLLEATPFDLIILDNIM
AGRTGLEWLEELRGSGFHRDVILITAFADLETAIKALRAGAADFVLKPFRSNQILNAIARCLDRGRLMRENFVLRRELKA
LPGVGAMVGASNATRSVRGMIERVGPMPTTVLVTGESGTGKEVTARSLHDVSSRAGKPFVPVNCAAIAPEIIESELFGHL
KGAFTGAASSREGLFFYAQGGTLFLDEVGELPPAMQSKLLRVIEDKKVRPVGAEREIPVDVRLIAATNCDLATAVAQGRF
RQDLYYRLNVVNIHLAPLRARAADVEPLAHLFMAELSAQLGVPPLDLTAGVLRALTRYDWPGNVRELRNVIERSLILGEF
PSDVVPDADEEPAAADVDALPQALGAVEKAHMLKVLGEAGGNRAEAARRLGVSRKTLDRKLKAWNA
>Mature_465_residues
ATTADAPQEAPHAASDIAFSPHLSGASILVVDDEPGMRNFLVRMLASRCRHVAEAADVAAASKLLEATPFDLIILDNIMA
GRTGLEWLEELRGSGFHRDVILITAFADLETAIKALRAGAADFVLKPFRSNQILNAIARCLDRGRLMRENFVLRRELKAL
PGVGAMVGASNATRSVRGMIERVGPMPTTVLVTGESGTGKEVTARSLHDVSSRAGKPFVPVNCAAIAPEIIESELFGHLK
GAFTGAASSREGLFFYAQGGTLFLDEVGELPPAMQSKLLRVIEDKKVRPVGAEREIPVDVRLIAATNCDLATAVAQGRFR
QDLYYRLNVVNIHLAPLRARAADVEPLAHLFMAELSAQLGVPPLDLTAGVLRALTRYDWPGNVRELRNVIERSLILGEFP
SDVVPDADEEPAAADVDALPQALGAVEKAHMLKVLGEAGGNRAEAARRLGVSRKTLDRKLKAWNA

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=448, Percent_Identity=38.6160714285714, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=41.7040358744395, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI1790299, Length=466, Percent_Identity=36.9098712446352, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1788905, Length=444, Percent_Identity=36.4864864864865, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1789233, Length=332, Percent_Identity=40.6626506024096, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789087, Length=330, Percent_Identity=44.2424242424242, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI87082117, Length=336, Percent_Identity=41.3690476190476, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1786524, Length=361, Percent_Identity=40.1662049861496, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1787583, Length=306, Percent_Identity=40.1960784313725, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI87082152, Length=312, Percent_Identity=40.0641025641026, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=314, Percent_Identity=36.624203821656, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1789828, Length=264, Percent_Identity=37.5, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI87081858, Length=280, Percent_Identity=33.9285714285714, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789809, Length=169, Percent_Identity=29.585798816568, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50158; Mature: 50027

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTADAPQEAPHAASDIAFSPHLSGASILVVDDEPGMRNFLVRMLASRCRHVAEAADVA
CCCCCCCCCCCCCCHHCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
AASKLLEATPFDLIILDNIMAGRTGLEWLEELRGSGFHRDVILITAFADLETAIKALRAG
HHHHHHHCCCCCEEEECHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCC
AADFVLKPFRSNQILNAIARCLDRGRLMRENFVLRRELKALPGVGAMVGASNATRSVRGM
CHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHH
IERVGPMPTTVLVTGESGTGKEVTARSLHDVSSRAGKPFVPVNCAAIAPEIIESELFGHL
HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KGAFTGAASSREGLFFYAQGGTLFLDEVGELPPAMQSKLLRVIEDKKVRPVGAEREIPVD
HHHHCCCCCCCCCEEEEECCCEEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VRLIAATNCDLATAVAQGRFRQDLYYRLNVVNIHLAPLRARAADVEPLAHLFMAELSAQL
EEEEEECCCHHHHHHHHHHHHHHHEEEEEEEEEEEECHHHHHCCHHHHHHHHHHHHHHHC
GVPPLDLTAGVLRALTRYDWPGNVRELRNVIERSLILGEFPSDVVPDADEEPAAADVDAL
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
PQALGAVEKAHMLKVLGEAGGNRAEAARRLGVSRKTLDRKLKAWNA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATTADAPQEAPHAASDIAFSPHLSGASILVVDDEPGMRNFLVRMLASRCRHVAEAADVA
CCCCCCCCCCCCCHHCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
AASKLLEATPFDLIILDNIMAGRTGLEWLEELRGSGFHRDVILITAFADLETAIKALRAG
HHHHHHHCCCCCEEEECHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCC
AADFVLKPFRSNQILNAIARCLDRGRLMRENFVLRRELKALPGVGAMVGASNATRSVRGM
CHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHH
IERVGPMPTTVLVTGESGTGKEVTARSLHDVSSRAGKPFVPVNCAAIAPEIIESELFGHL
HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KGAFTGAASSREGLFFYAQGGTLFLDEVGELPPAMQSKLLRVIEDKKVRPVGAEREIPVD
HHHHCCCCCCCCCEEEEECCCEEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VRLIAATNCDLATAVAQGRFRQDLYYRLNVVNIHLAPLRARAADVEPLAHLFMAELSAQL
EEEEEECCCHHHHHHHHHHHHHHHEEEEEEEEEEEECHHHHHCCHHHHHHHHHHHHHHHC
GVPPLDLTAGVLRALTRYDWPGNVRELRNVIERSLILGEFPSDVVPDADEEPAAADVDAL
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
PQALGAVEKAHMLKVLGEAGGNRAEAARRLGVSRKTLDRKLKAWNA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]