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The map label for this gene is rnhB

Identifier: 154245214

GI number: 154245214

Start: 1456200

End: 1456949

Strand: Direct

Name: rnhB

Synonym: Xaut_1266

Alternate gene names: 154245214

Gene position: 1456200-1456949 (Clockwise)

Preceding gene: 154245196

Following gene: 154245217

Centisome position: 27.43

GC content: 72.67

Gene sequence:

>750_bases
ATGGCGCCGCGTCCGAAAGCCCCTCCCCAGCCCGCAGAGCCCGATCCCGCGCTGCCAAGGCCACGCGGCCGGCCGCCGAA
GGCGGGGGCTGTCACAGCAGGCTGGGTGGGCCTCGACTTCACACGTGAGCGCGCGCTCTACGCCGACGGGCGCGCCCCCG
TCGCCGGTGCCGACGAGGTGGGTCGGGGCCCGCTTGCAGGCCCGGTGGTGGCGGCGGCCGTGGTGCTGGATCCGGCGCGG
GTGCCGCAGGGGCTCGATGATTCGAAGAAGCTGACGCGGGCAAAACGCGAGTCGCTTTATCTGGAGATCTGCGCCACCGC
CGAAGTCGCCATTGCCCTCGCCCCGCCGGAGCGCATCGACCGGGACAACATCCGCCAGGCGACGCTCTGGGCGCTCGCGA
ACGCGGTGCGGGGCCTGCCGTGCCGGCCGGCGTTCCTTCTCGTGGACGGAAATGATCCGCCGCGGGTCGACTGCGAGGTG
GAGGCCATCGTGGGGGGTGACGGGCTCGTCGCTTCCATCGCGGCGGCGTCCATCGTGGCCAAGGTGGTGCGCGACCGGTT
GATGGCGGGTGTCGGCGCCGCCTTTCCCGCCTACGGGTTCGAGCGCCACATGGGCTATGGCACCCGGGAGCATGGCGCGG
CGCTGAAGGCCCACGGGCCATGCCTGCACCACCGTCGGTCGTTCGCGCCGGTGCGTGAGCAGCAGCTTGGCCTGTTTCCA
GCCCCCGGGGAGCTGGAGGAGGCGGACTGA

Upstream 100 bases:

>100_bases
ATGCCCAGCCCGTCGCCGGGTTCCATGGTATCAAGACGCCAGGGCCGCGCATCGACCGAAGGTGGCTCGGTTCACCCTCA
GATCAGGGTTTGTCTTCCCC

Downstream 100 bases:

>100_bases
GGGGTGCGCGTCCCTCAGTGCAGATCCTTCAGTGCAGTCCTCAGGACAAGCCGGTCAGTGGTAGCCCTCGCCCTCGCGGA
CCTTGCCGCGGAAGATCCAG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MAPRPKAPPQPAEPDPALPRPRGRPPKAGAVTAGWVGLDFTRERALYADGRAPVAGADEVGRGPLAGPVVAAAVVLDPAR
VPQGLDDSKKLTRAKRESLYLEICATAEVAIALAPPERIDRDNIRQATLWALANAVRGLPCRPAFLLVDGNDPPRVDCEV
EAIVGGDGLVASIAAASIVAKVVRDRLMAGVGAAFPAYGFERHMGYGTREHGAALKAHGPCLHHRRSFAPVREQQLGLFP
APGELEEAD

Sequences:

>Translated_249_residues
MAPRPKAPPQPAEPDPALPRPRGRPPKAGAVTAGWVGLDFTRERALYADGRAPVAGADEVGRGPLAGPVVAAAVVLDPAR
VPQGLDDSKKLTRAKRESLYLEICATAEVAIALAPPERIDRDNIRQATLWALANAVRGLPCRPAFLLVDGNDPPRVDCEV
EAIVGGDGLVASIAAASIVAKVVRDRLMAGVGAAFPAYGFERHMGYGTREHGAALKAHGPCLHHRRSFAPVREQQLGLFP
APGELEEAD
>Mature_248_residues
APRPKAPPQPAEPDPALPRPRGRPPKAGAVTAGWVGLDFTRERALYADGRAPVAGADEVGRGPLAGPVVAAAVVLDPARV
PQGLDDSKKLTRAKRESLYLEICATAEVAIALAPPERIDRDNIRQATLWALANAVRGLPCRPAFLLVDGNDPPRVDCEVE
AIVGGDGLVASIAAASIVAKVVRDRLMAGVGAAFPAYGFERHMGYGTREHGAALKAHGPCLHHRRSFAPVREQQLGLFPA
PGELEEAD

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=186, Percent_Identity=51.0752688172043, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_XANP2 (A7IES2)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416172.1
- ProteinModelPortal:   A7IES2
- SMR:   A7IES2
- STRING:   A7IES2
- GeneID:   5423284
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_1266
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   XAUT78245:XAUT_1266-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 26234; Mature: 26103

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPRPKAPPQPAEPDPALPRPRGRPPKAGAVTAGWVGLDFTRERALYADGRAPVAGADEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECEEECCHHHCCEEEECCCCCCCCCHHC
GRGPLAGPVVAAAVVLDPARVPQGLDDSKKLTRAKRESLYLEICATAEVAIALAPPERID
CCCCCCHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHEEEEEECCCEEEEEECCHHHCC
RDNIRQATLWALANAVRGLPCRPAFLLVDGNDPPRVDCEVEAIVGGDGLVASIAAASIVA
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
KVVRDRLMAGVGAAFPAYGFERHMGYGTREHGAALKAHGPCLHHRRSFAPVREQQLGLFP
HHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHCCEECCCCCHHHHHHCCCCHHHHHCCCCC
APGELEEAD
CCCCCCCCC
>Mature Secondary Structure 
APRPKAPPQPAEPDPALPRPRGRPPKAGAVTAGWVGLDFTRERALYADGRAPVAGADEV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECEEECCHHHCCEEEECCCCCCCCCHHC
GRGPLAGPVVAAAVVLDPARVPQGLDDSKKLTRAKRESLYLEICATAEVAIALAPPERID
CCCCCCHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHEEEEEECCCEEEEEECCHHHCC
RDNIRQATLWALANAVRGLPCRPAFLLVDGNDPPRVDCEVEAIVGGDGLVASIAAASIVA
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
KVVRDRLMAGVGAAFPAYGFERHMGYGTREHGAALKAHGPCLHHRRSFAPVREQQLGLFP
HHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHCCEECCCCCHHHHHHCCCCHHHHHCCCCC
APGELEEAD
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA