Click here to switch to the map view.

The map label for this gene is yogA [H]

Identifier: 154245206

GI number: 154245206

Start: 1447539

End: 1448561

Strand: Reverse

Name: yogA [H]

Synonym: Xaut_1258

Alternate gene names: 154245206

Gene position: 1448561-1447539 (Counterclockwise)

Preceding gene: 154245207

Following gene: 154245205

Centisome position: 27.29

GC content: 66.08

Gene sequence:

>1023_bases
ATGCGTGGCCTCCAGCTCGTCTCCGACCGCAGCCTCGAACTCGTCGACCTGCCCGAACCCGACGCCCCCGGCGCCGGCGA
GGTGCAGATCCGCGTCAAGGCGCTGGCGCTCAACCATATCGACGTGTGGGGCTGGCGCGGCATGGCCTTCGCCAAGCGCA
AGATGCCCCTCGTGGTGGGCGCGGAGGCCGCCGGCGAGATCGTGGCGCTGGGCGCGGACGTGCGCGGCCTGAAGGTGGGG
CAGACGGTGGCCATGTACGGCGCCATGACTTGTGGCCACTGCGTCAACTGCCTTAAGGGGCGGGATAATCTCTGCCAGAA
CGTGGGCGGCGTGCTGGGCTTCCACATCGACGGCTTCGCCCGCGACGTGATCAACATGCCCGAGCGCCTCGTCATCCCGG
CGCCCGAGGGCGTCTCCTTCGAAGATGCGGCCTGCGCCGGCATCACATTCTCCACCGTCGAGCACATGCTGTTCGACAAC
GCGCAGCTGGAACAGGGCGAGACCGTGCTGGTCCATGCCGGCGGATCGGGCATCGGCTCCGCCGCCATCCGGCTCGCCAA
GGACGTGGGCGCCACCGTCATCACCACGGTCGGCGACGACGAGAAGCTGGAGAAGGCGAAGGCGCTGGGCGCCGACCACG
TCATCAATTATCGCAAGGACCGGTTCGAGCACGAGGTCCGCAAGATCACCAAGAAGGTGGGCGTGGACGTGGTGTTCGAG
CATGTGGGCGCCGACACCTGGAATGCCTCGCTGCTGTCCATGAAGCCCGGGGCGCGCCTCGTCACCTGCGGCTCCACCTC
CGGCGTGAGCGTGCAGATGAACCTGATGCAGCTGTTCCAGCGCCAGTACAAGATCTTCGGCTCGTTCGGCGCCACCATCC
GCAATGTGTCGGAGGGCCTTGAGAAGATGGGCCGTGGCATCAAGCCGGTGATCGATACTGTGGTGCCGCTGGAAAACTTC
AACGAGGGCCTGGAGCGGCTCGAGAGCCGCAAGGTCTTCGGCAAAATCGTGGTGAAGTTCTAA

Upstream 100 bases:

>100_bases
CCCGGCGCGGGCTATATGACCGGCGCCATATTGCCGGTGGATGGCGGGCTTTCCGCCTCGCTCGCCGCCCACCGCTGACC
CAACTTCCGAGAAAAAAAGA

Downstream 100 bases:

>100_bases
GGGCTCGACGCGGCGCGCTCGGCCGTGACCCGCTTGTCCCACACCGTCCGCCGCCTGCTCCTCCGGCTGCGTCTTGCGCT
GCAGCCGGTAGTGGAAGTGC

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRGLQLVSDRSLELVDLPEPDAPGAGEVQIRVKALALNHIDVWGWRGMAFAKRKMPLVVGAEAAGEIVALGADVRGLKVG
QTVAMYGAMTCGHCVNCLKGRDNLCQNVGGVLGFHIDGFARDVINMPERLVIPAPEGVSFEDAACAGITFSTVEHMLFDN
AQLEQGETVLVHAGGSGIGSAAIRLAKDVGATVITTVGDDEKLEKAKALGADHVINYRKDRFEHEVRKITKKVGVDVVFE
HVGADTWNASLLSMKPGARLVTCGSTSGVSVQMNLMQLFQRQYKIFGSFGATIRNVSEGLEKMGRGIKPVIDTVVPLENF
NEGLERLESRKVFGKIVVKF

Sequences:

>Translated_340_residues
MRGLQLVSDRSLELVDLPEPDAPGAGEVQIRVKALALNHIDVWGWRGMAFAKRKMPLVVGAEAAGEIVALGADVRGLKVG
QTVAMYGAMTCGHCVNCLKGRDNLCQNVGGVLGFHIDGFARDVINMPERLVIPAPEGVSFEDAACAGITFSTVEHMLFDN
AQLEQGETVLVHAGGSGIGSAAIRLAKDVGATVITTVGDDEKLEKAKALGADHVINYRKDRFEHEVRKITKKVGVDVVFE
HVGADTWNASLLSMKPGARLVTCGSTSGVSVQMNLMQLFQRQYKIFGSFGATIRNVSEGLEKMGRGIKPVIDTVVPLENF
NEGLERLESRKVFGKIVVKF
>Mature_340_residues
MRGLQLVSDRSLELVDLPEPDAPGAGEVQIRVKALALNHIDVWGWRGMAFAKRKMPLVVGAEAAGEIVALGADVRGLKVG
QTVAMYGAMTCGHCVNCLKGRDNLCQNVGGVLGFHIDGFARDVINMPERLVIPAPEGVSFEDAACAGITFSTVEHMLFDN
AQLEQGETVLVHAGGSGIGSAAIRLAKDVGATVITTVGDDEKLEKAKALGADHVINYRKDRFEHEVRKITKKVGVDVVFE
HVGADTWNASLLSMKPGARLVTCGSTSGVSVQMNLMQLFQRQYKIFGSFGATIRNVSEGLEKMGRGIKPVIDTVVPLENF
NEGLERLESRKVFGKIVVKF

Specific function: Threonine catabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=339, Percent_Identity=28.023598820059, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI22538444, Length=339, Percent_Identity=28.023598820059, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=27.3504273504274, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI18379349, Length=337, Percent_Identity=24.3323442136499, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI194239674, Length=312, Percent_Identity=24.0384615384615, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI13236495, Length=312, Percent_Identity=24.0384615384615, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI34577061, Length=346, Percent_Identity=28.3236994219653, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI156627571, Length=329, Percent_Identity=27.9635258358663, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4501929, Length=348, Percent_Identity=28.1609195402299, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI41872631, Length=171, Percent_Identity=30.4093567251462, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4501933, Length=359, Percent_Identity=27.2980501392758, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI197927207, Length=178, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI226059159, Length=141, Percent_Identity=31.2056737588652, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI226059133, Length=141, Percent_Identity=31.2056737588652, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790045, Length=348, Percent_Identity=28.1609195402299, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790485, Length=262, Percent_Identity=29.7709923664122, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787863, Length=219, Percent_Identity=34.2465753424658, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788073, Length=289, Percent_Identity=28.719723183391, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI226510992, Length=158, Percent_Identity=34.1772151898734, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082125, Length=361, Percent_Identity=27.7008310249307, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081918, Length=323, Percent_Identity=24.4582043343653, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786518, Length=229, Percent_Identity=28.82096069869, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082401, Length=325, Percent_Identity=24, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788075, Length=346, Percent_Identity=23.6994219653179, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790718, Length=296, Percent_Identity=24.3243243243243, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=290, Percent_Identity=29.3103448275862, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562878, Length=273, Percent_Identity=26.3736263736264, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=337, Percent_Identity=24.0356083086053, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17507255, Length=342, Percent_Identity=24.2690058479532, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=332, Percent_Identity=22.8915662650602, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=336, Percent_Identity=26.7857142857143, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=336, Percent_Identity=26.1904761904762, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=25.3012048192771, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319621, Length=337, Percent_Identity=25.5192878338279, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319520, Length=337, Percent_Identity=26.1127596439169, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322619, Length=342, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=342, Percent_Identity=26.0233918128655, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=250, Percent_Identity=28.8, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323099, Length=325, Percent_Identity=24.9230769230769, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19920632, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221330659, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24581345, Length=227, Percent_Identity=28.1938325991189, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36585; Mature: 36585

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLQLVSDRSLELVDLPEPDAPGAGEVQIRVKALALNHIDVWGWRGMAFAKRKMPLVVG
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEEEECCEEECCCCCHHHHHHCCCEEEE
AEAAGEIVALGADVRGLKVGQTVAMYGAMTCGHCVNCLKGRDNLCQNVGGVLGFHIDGFA
CCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEHHHHH
RDVINMPERLVIPAPEGVSFEDAACAGITFSTVEHMLFDNAQLEQGETVLVHAGGSGIGS
HHHHCCCCEEEEECCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIRLAKDVGATVITTVGDDEKLEKAKALGADHVINYRKDRFEHEVRKITKKVGVDVVFE
HHHHHHHHCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
HVGADTWNASLLSMKPGARLVTCGSTSGVSVQMNLMQLFQRQYKIFGSFGATIRNVSEGL
HHCCCCCCCEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMGRGIKPVIDTVVPLENFNEGLERLESRKVFGKIVVKF
HHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MRGLQLVSDRSLELVDLPEPDAPGAGEVQIRVKALALNHIDVWGWRGMAFAKRKMPLVVG
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEEEECCEEECCCCCHHHHHHCCCEEEE
AEAAGEIVALGADVRGLKVGQTVAMYGAMTCGHCVNCLKGRDNLCQNVGGVLGFHIDGFA
CCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEHHHHH
RDVINMPERLVIPAPEGVSFEDAACAGITFSTVEHMLFDNAQLEQGETVLVHAGGSGIGS
HHHHCCCCEEEEECCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIRLAKDVGATVITTVGDDEKLEKAKALGADHVINYRKDRFEHEVRKITKKVGVDVVFE
HHHHHHHHCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
HVGADTWNASLLSMKPGARLVTCGSTSGVSVQMNLMQLFQRQYKIFGSFGATIRNVSEGL
HHCCCCCCCEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMGRGIKPVIDTVVPLENFNEGLERLESRKVFGKIVVKF
HHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]