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The map label for this gene is gntR [H]

Identifier: 154245184

GI number: 154245184

Start: 1421504

End: 1422598

Strand: Direct

Name: gntR [H]

Synonym: Xaut_1236

Alternate gene names: 154245184

Gene position: 1421504-1422598 (Clockwise)

Preceding gene: 154245181

Following gene: 154245185

Centisome position: 26.78

GC content: 69.68

Gene sequence:

>1095_bases
ATGCCGCTGTCGGTGCCGGCTATCAAGCGGAAAAACGCGCCCATGTCCCAGCGGTCTTCGAGTGGATCGTCCGGCAACCC
CTCCCGCGGGTCGCGCGCCAGCGGCCGTCCCACCCTCGCGGAACTGGCGCAGATCGCCGGCGTCTCGCCGATCACCGCCT
CTCGTGCCCTGCGCGGCGTCGCCAGTGTGGATCCCGATCTCGCAAAGCGCGTGCGCGAGGCTGCGGCCGCGCTCAATTAC
GTGGCCAACCCTGCCGCGCGCACCCTCGCCTCCGCCCACAGCGATGCGGTGGCGGTGCTCATTCCCTCTCTCTCCAACCT
GCTCTTCATCGACACGCTGGAGGCGATCCACGATGTGCTGATGCCGCGCGGCCTGGAGGTGCTGATCGGCAACTTCCACT
ATTCGCCGGAGGAGGAGGAGAAGCTTGTCCGCAACTACCTCGCCTACCAGCCGCGCGGCATTCTGCTCACCGGGCTGGAG
CAGACGCCGGCCACGCGCAGCCTGCTGAAGGCGAGCGGCATTCCCGTCGTCTACATGATGGAGCTGAGCCGGGAGATGGG
GGTTCACAGCGTCGGCTTCTCGCAGGAGGAGTCCGGCGCGGCGGTCGCCCGTCACCTGCTCGCCCGGGGGCGGCGCCATC
TGGCCTATGTGGCGGCCCAACTCGATCCGCGCGCGCTGGAACGCGGCCTCGGTTTCCAGCGGGTGCTCGCCGGGGAGCGC
GAGGTGCGGCCCCCGGTGTGGCTTTCGGTGCCCGAGCCCTCGTCGGTGGCCCTCGGTGGCGAGCTGTTCGTGCGCCTTCT
GGAAGCCTATCCCGACATCGACGGCATTTTCTTCTGCAATGACGATCTCGCGCAGGGCGCGATCTTCGAGGCGACGCGAC
GGCAGGTTCCCATTCCCGGCCGGGTCGCCGTGGTGGGCTTCAATGACCTGCCGCTGTCGGCCCACATGGCGCCGCGCCTC
ACCTCCATCCGCACCCCGCGGGCCAAGGTGGGGGAGGCGGCGGCGCGCCGGCTCGTGGCCCTCATGGAAGGGGACTGCCG
CGCCGAGCCGGCCATTGATCTCGGTTTCGAGCTGGTGGAGCGGGAGAGCAGCTGA

Upstream 100 bases:

>100_bases
CCTTAAGTCGAGTACATCCTTAACTTCCAACGACATAGCGCTCCGGTTCCTGTGGAGCGCGCAAGTTTCTTGCTTGATGC
CGTCAAGATAGCGTTATCTT

Downstream 100 bases:

>100_bases
GCGCGATCCGGCCGCACCGGATCTTGACGGCGCCCCGGCGGGCATGGTGTAAGCGTTCTGCGCTCGCTCTGCGGCGCCGT
AAGCGTCCGACGTCAGGCAA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MPLSVPAIKRKNAPMSQRSSSGSSGNPSRGSRASGRPTLAELAQIAGVSPITASRALRGVASVDPDLAKRVREAAAALNY
VANPAARTLASAHSDAVAVLIPSLSNLLFIDTLEAIHDVLMPRGLEVLIGNFHYSPEEEEKLVRNYLAYQPRGILLTGLE
QTPATRSLLKASGIPVVYMMELSREMGVHSVGFSQEESGAAVARHLLARGRRHLAYVAAQLDPRALERGLGFQRVLAGER
EVRPPVWLSVPEPSSVALGGELFVRLLEAYPDIDGIFFCNDDLAQGAIFEATRRQVPIPGRVAVVGFNDLPLSAHMAPRL
TSIRTPRAKVGEAAARRLVALMEGDCRAEPAIDLGFELVERESS

Sequences:

>Translated_364_residues
MPLSVPAIKRKNAPMSQRSSSGSSGNPSRGSRASGRPTLAELAQIAGVSPITASRALRGVASVDPDLAKRVREAAAALNY
VANPAARTLASAHSDAVAVLIPSLSNLLFIDTLEAIHDVLMPRGLEVLIGNFHYSPEEEEKLVRNYLAYQPRGILLTGLE
QTPATRSLLKASGIPVVYMMELSREMGVHSVGFSQEESGAAVARHLLARGRRHLAYVAAQLDPRALERGLGFQRVLAGER
EVRPPVWLSVPEPSSVALGGELFVRLLEAYPDIDGIFFCNDDLAQGAIFEATRRQVPIPGRVAVVGFNDLPLSAHMAPRL
TSIRTPRAKVGEAAARRLVALMEGDCRAEPAIDLGFELVERESS
>Mature_363_residues
PLSVPAIKRKNAPMSQRSSSGSSGNPSRGSRASGRPTLAELAQIAGVSPITASRALRGVASVDPDLAKRVREAAAALNYV
ANPAARTLASAHSDAVAVLIPSLSNLLFIDTLEAIHDVLMPRGLEVLIGNFHYSPEEEEKLVRNYLAYQPRGILLTGLEQ
TPATRSLLKASGIPVVYMMELSREMGVHSVGFSQEESGAAVARHLLARGRRHLAYVAAQLDPRALERGLGFQRVLAGERE
VRPPVWLSVPEPSSVALGGELFVRLLEAYPDIDGIFFCNDDLAQGAIFEATRRQVPIPGRVAVVGFNDLPLSAHMAPRLT
SIRTPRAKVGEAAARRLVALMEGDCRAEPAIDLGFELVERESS

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=34.6749226006192, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1790715, Length=324, Percent_Identity=31.1728395061728, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789068, Length=343, Percent_Identity=25.3644314868805, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788474, Length=308, Percent_Identity=27.5974025974026, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=24.5454545454545, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=26.0188087774295, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787948, Length=341, Percent_Identity=25.2199413489736, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790194, Length=317, Percent_Identity=24.6056782334385, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789202, Length=303, Percent_Identity=23.7623762376238, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786540, Length=311, Percent_Identity=26.0450160771704, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 39099; Mature: 38968

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSVPAIKRKNAPMSQRSSSGSSGNPSRGSRASGRPTLAELAQIAGVSPITASRALRGV
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
ASVDPDLAKRVREAAAALNYVANPAARTLASAHSDAVAVLIPSLSNLLFIDTLEAIHDVL
HCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHH
MPRGLEVLIGNFHYSPEEEEKLVRNYLAYQPRGILLTGLEQTPATRSLLKASGIPVVYMM
CCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCCEEEHH
ELSREMGVHSVGFSQEESGAAVARHLLARGRRHLAYVAAQLDPRALERGLGFQRVLAGER
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCHHHHHCCCC
EVRPPVWLSVPEPSSVALGGELFVRLLEAYPDIDGIFFCNDDLAQGAIFEATRRQVPIPG
CCCCCEEEECCCCCCEEECHHHHHHHHHHCCCCCEEEEECCHHHCCHHHHHHHCCCCCCC
RVAVVGFNDLPLSAHMAPRLTSIRTPRAKVGEAAARRLVALMEGDCRAEPAIDLGFELVE
EEEEEECCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RESS
CCCC
>Mature Secondary Structure 
PLSVPAIKRKNAPMSQRSSSGSSGNPSRGSRASGRPTLAELAQIAGVSPITASRALRGV
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
ASVDPDLAKRVREAAAALNYVANPAARTLASAHSDAVAVLIPSLSNLLFIDTLEAIHDVL
HCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHH
MPRGLEVLIGNFHYSPEEEEKLVRNYLAYQPRGILLTGLEQTPATRSLLKASGIPVVYMM
CCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCCEEEHH
ELSREMGVHSVGFSQEESGAAVARHLLARGRRHLAYVAAQLDPRALERGLGFQRVLAGER
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCHHHHHCCCC
EVRPPVWLSVPEPSSVALGGELFVRLLEAYPDIDGIFFCNDDLAQGAIFEATRRQVPIPG
CCCCCEEEECCCCCCEEECHHHHHHHHHHCCCCCEEEEECCHHHCCHHHHHHHCCCCCCC
RVAVVGFNDLPLSAHMAPRLTSIRTPRAKVGEAAARRLVALMEGDCRAEPAIDLGFELVE
EEEEEECCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RESS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]