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The map label for this gene is glnII [H]

Identifier: 154245089

GI number: 154245089

Start: 1312051

End: 1313085

Strand: Direct

Name: glnII [H]

Synonym: Xaut_1141

Alternate gene names: 154245089

Gene position: 1312051-1313085 (Clockwise)

Preceding gene: 154245086

Following gene: 154245090

Centisome position: 24.71

GC content: 63.67

Gene sequence:

>1035_bases
ATGCCAAAGTTTAAACTCGAGTATATCTGGCTGGACGGTTACACCCCGACCCCGAATCTGCGTGGCAAGACGCAGATCAA
GGAATACGACGTGTTTCCGACCCTCGAGCAACTGCCGCTGTGGGGCTTCGATGGCAGCTCCACCCAGCAGGCCGAAGGCC
GCAGCTCCGACTGCGTGCTGAAGCCCGTGGCGGTCTATCCCGATCCGGCCCGCACCGACGGCGCCCTGGTCATGTGCGAA
GTGATGATGCCCGATGGCGTCACCCCGCACCCGACCAACAAGCGCGCCACCATCCTCGACGATGCCGGCGCCTGGTTCGG
TTTCGAGCAGGAATACTTCTTCTACAAGGACGGCCGTCCCCTCGGCTTCCCCGAGCACGGCTATCCGGCGCCCCAGGGCC
CGTACTACACCGGCGTCGGCTTCAAGAATGTCGGCAACATCGCCCGCCAGATCGTCGAGGAGCACCTCGACCTCTGCCTC
GCGGCCGGCATCAACCACGAAGGCATCAACGCGGAAGTCGCGAAGGGCCAGTGGGAATTCCAGATCTTCGGCAAGGGCTC
CAAGAAGGCGGCCGACGAAGTGTGGATGGCGCGCTACCTGCTGCTCCGTCTCACCGAGAAGTATGGCGTGGACATCGAGT
TCCACTGCAAGCCGCTCGGCGACACCGACTGGAACGGCTCGGGCATGCACGCCAACTTCTCCACCACCTATCTGCGCGAA
GTGGGCGGCAAGGCCTATTTCGAGGCGCTGATGGCGGCGTTCGAGGCCAACCTCGAGGACCACATCGCTGTCTACGGCCC
GGACAACCACATGCGCCTCACCGGCAAGCATGAGACCGCGCCGTGGAACAAGTTCTCCTATGGCGTGGCCGACCGTGGCG
CGTCGATCCGCGTGCCCCACTCGTTCGTGAAGAACGACTACAAGGGTTACCTTGAGGATCGCCGCCCCAACTCCATGGGC
GACCCCTACCAGATCGCCTCGCAGATCCTGAAGACCATCGCGTCGGTTCCCACCGACGTGTCGGCTGCGGCCTGA

Upstream 100 bases:

>100_bases
GCTAGAGAGATGGCGGCTCAAACGGTCAGTGGATTCTGCGCGGCCGGACGCTCAGTCACGAGTTCCAAGATCTCACGTCA
TCGGCTTATGAGAGACTGCA

Downstream 100 bases:

>100_bases
TCTTACAAGCCACGGCGCGTTCCGCGCGCCGTGGCCCTCCTTCGCGTATCCGCATTTTCGCCGGGCCTTGCCGTTTTGGC
TCCCGTGCGCGTCGCCCGAG

Product: glutamate--ammonia ligase

Products: NA

Alternate protein names: Glutamate--ammonia ligase II; Glutamine synthetase II; GSII [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPKFKLEYIWLDGYTPTPNLRGKTQIKEYDVFPTLEQLPLWGFDGSSTQQAEGRSSDCVLKPVAVYPDPARTDGALVMCE
VMMPDGVTPHPTNKRATILDDAGAWFGFEQEYFFYKDGRPLGFPEHGYPAPQGPYYTGVGFKNVGNIARQIVEEHLDLCL
AAGINHEGINAEVAKGQWEFQIFGKGSKKAADEVWMARYLLLRLTEKYGVDIEFHCKPLGDTDWNGSGMHANFSTTYLRE
VGGKAYFEALMAAFEANLEDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSMG
DPYQIASQILKTIASVPTDVSAAA

Sequences:

>Translated_344_residues
MPKFKLEYIWLDGYTPTPNLRGKTQIKEYDVFPTLEQLPLWGFDGSSTQQAEGRSSDCVLKPVAVYPDPARTDGALVMCE
VMMPDGVTPHPTNKRATILDDAGAWFGFEQEYFFYKDGRPLGFPEHGYPAPQGPYYTGVGFKNVGNIARQIVEEHLDLCL
AAGINHEGINAEVAKGQWEFQIFGKGSKKAADEVWMARYLLLRLTEKYGVDIEFHCKPLGDTDWNGSGMHANFSTTYLRE
VGGKAYFEALMAAFEANLEDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSMG
DPYQIASQILKTIASVPTDVSAAA
>Mature_343_residues
PKFKLEYIWLDGYTPTPNLRGKTQIKEYDVFPTLEQLPLWGFDGSSTQQAEGRSSDCVLKPVAVYPDPARTDGALVMCEV
MMPDGVTPHPTNKRATILDDAGAWFGFEQEYFFYKDGRPLGFPEHGYPAPQGPYYTGVGFKNVGNIARQIVEEHLDLCLA
AGINHEGINAEVAKGQWEFQIFGKGSKKAADEVWMARYLLLRLTEKYGVDIEFHCKPLGDTDWNGSGMHANFSTTYLREV
GGKAYFEALMAAFEANLEDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSMGD
PYQIASQILKTIASVPTDVSAAA

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI74271826, Length=343, Percent_Identity=43.1486880466472, Blast_Score=251, Evalue=5e-67,
Organism=Homo sapiens, GI74271837, Length=343, Percent_Identity=43.1486880466472, Blast_Score=251, Evalue=5e-67,
Organism=Homo sapiens, GI19923206, Length=343, Percent_Identity=43.1486880466472, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI115532980, Length=344, Percent_Identity=47.093023255814, Blast_Score=280, Evalue=6e-76,
Organism=Caenorhabditis elegans, GI115532978, Length=344, Percent_Identity=47.093023255814, Blast_Score=280, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17554028, Length=345, Percent_Identity=45.2173913043478, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17540008, Length=346, Percent_Identity=45.9537572254335, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17538856, Length=345, Percent_Identity=42.6086956521739, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17551038, Length=318, Percent_Identity=40.251572327044, Blast_Score=209, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6325292, Length=335, Percent_Identity=46.865671641791, Blast_Score=280, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24641292, Length=339, Percent_Identity=47.4926253687316, Blast_Score=280, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24641290, Length=339, Percent_Identity=47.4926253687316, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI281360453, Length=343, Percent_Identity=45.1895043731778, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI17136208, Length=343, Percent_Identity=45.1895043731778, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24580558, Length=343, Percent_Identity=45.1895043731778, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI45554830, Length=268, Percent_Identity=48.8805970149254, Blast_Score=231, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 38383; Mature: 38251

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKFKLEYIWLDGYTPTPNLRGKTQIKEYDVFPTLEQLPLWGFDGSSTQQAEGRSSDCVL
CCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCHHHCEEECCCCCCCCCCCCCCCCEEE
KPVAVYPDPARTDGALVMCEVMMPDGVTPHPTNKRATILDDAGAWFGFEQEYFFYKDGRP
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCC
LGFPEHGYPAPQGPYYTGVGFKNVGNIARQIVEEHLDLCLAAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEE
QIFGKGSKKAADEVWMARYLLLRLTEKYGVDIEFHCKPLGDTDWNGSGMHANFSTTYLRE
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCHHHHHHH
VGGKAYFEALMAAFEANLEDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIRVPH
HCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCCCCCCCEECCCCCCCCEEECCH
SFVKNDYKGYLEDRRPNSMGDPYQIASQILKTIASVPTDVSAAA
HHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PKFKLEYIWLDGYTPTPNLRGKTQIKEYDVFPTLEQLPLWGFDGSSTQQAEGRSSDCVL
CCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCHHHCEEECCCCCCCCCCCCCCCCEEE
KPVAVYPDPARTDGALVMCEVMMPDGVTPHPTNKRATILDDAGAWFGFEQEYFFYKDGRP
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCC
LGFPEHGYPAPQGPYYTGVGFKNVGNIARQIVEEHLDLCLAAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEE
QIFGKGSKKAADEVWMARYLLLRLTEKYGVDIEFHCKPLGDTDWNGSGMHANFSTTYLRE
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCHHHHHHH
VGGKAYFEALMAAFEANLEDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIRVPH
HCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCCCCCCCEECCCCCCCCEEECCH
SFVKNDYKGYLEDRRPNSMGDPYQIASQILKTIASVPTDVSAAA
HHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]