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The map label for this gene is pcaI [H]

Identifier: 154245068

GI number: 154245068

Start: 1290384

End: 1291061

Strand: Reverse

Name: pcaI [H]

Synonym: Xaut_1120

Alternate gene names: 154245068

Gene position: 1291061-1290384 (Counterclockwise)

Preceding gene: 154245069

Following gene: 154245067

Centisome position: 24.32

GC content: 68.14

Gene sequence:

>678_bases
ATGATCGACAAGACCAGGCCCGACACGCAAAGCTGCGTCGCCGACATTCCGGACGGGGCGACCCTGCTGGTGGGCGGCTT
CGGCGGCGCCGGCATGCCCCACGAGCTGATCGAGGCGGTGATCGCCCGCGCGCCGAAGGACCTCACCATCATCTCCAACA
ATGCCGGCAACGGCACCACCGGGCTGGCCGCCCTGCTGGCGGCGGGGCTGGTGAAGAAGGTGGTGTGCTCCTTCCCCCGC
CAGGCGGACTCGTTTGTGTTCGACAAGCTCTATCGAGAGGGCAAGCTGGAGCTGGAACTGGTGCCCCAGGGCAATCTGGT
GGAGCGCATCCGCGCCGGCGGCGCCGGCATCGGCGCCTTCTTCACCCCCACCGGCTACGGCACCCCCATCGCGGCCGGCA
AGGAGACGCGGCAGATCGACGGGCGCAACTATGTGCTGGAATATCCGCTGAAGGCCGATTTCGCCCTCATCAAGGCCCGG
CGCGGCGATCGCTGGGGCAACCTCACCTATCGCAAGACCGCGCGCAATTTCGGTCCGGTCATGGCCACCGCGGCCACCAT
CACCGTGGCGCAGGTGGAGGACATCGTTCCCCTCGGGACGCTCGATCCGGAAGACATCGTCACCCCCGGCGTGTTCGTGG
ACCGCGTCGTGGCCATCGGCACGGGAGCCGCCCAATGA

Upstream 100 bases:

>100_bases
AGCTGCACACCCTGCTCTCCTCCCTGCCGCTCTTCCCCTTCATGGACATCACTGTGACGGCGCTGGCACGCCATCCGTCG
GCGATCTGAGGAGCCCGCCC

Downstream 100 bases:

>100_bases
GCGACATCGCCTTCACGCCCTGGACGCGCGCCGAGATGGCGCAGCGCATCGCCGCCGACATTCCGGACGGCGCCATCGTC
AACATCGGCATCGGCATGCC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIDKTRPDTQSCVADIPDGATLLVGGFGGAGMPHELIEAVIARAPKDLTIISNNAGNGTTGLAALLAAGLVKKVVCSFPR
QADSFVFDKLYREGKLELELVPQGNLVERIRAGGAGIGAFFTPTGYGTPIAAGKETRQIDGRNYVLEYPLKADFALIKAR
RGDRWGNLTYRKTARNFGPVMATAATITVAQVEDIVPLGTLDPEDIVTPGVFVDRVVAIGTGAAQ

Sequences:

>Translated_225_residues
MIDKTRPDTQSCVADIPDGATLLVGGFGGAGMPHELIEAVIARAPKDLTIISNNAGNGTTGLAALLAAGLVKKVVCSFPR
QADSFVFDKLYREGKLELELVPQGNLVERIRAGGAGIGAFFTPTGYGTPIAAGKETRQIDGRNYVLEYPLKADFALIKAR
RGDRWGNLTYRKTARNFGPVMATAATITVAQVEDIVPLGTLDPEDIVTPGVFVDRVVAIGTGAAQ
>Mature_225_residues
MIDKTRPDTQSCVADIPDGATLLVGGFGGAGMPHELIEAVIARAPKDLTIISNNAGNGTTGLAALLAAGLVKKVVCSFPR
QADSFVFDKLYREGKLELELVPQGNLVERIRAGGAGIGAFFTPTGYGTPIAAGKETRQIDGRNYVLEYPLKADFALIKAR
RGDRWGNLTYRKTARNFGPVMATAATITVAQVEDIVPLGTLDPEDIVTPGVFVDRVVAIGTGAAQ

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=232, Percent_Identity=44.8275862068966, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI11545841, Length=232, Percent_Identity=43.9655172413793, Blast_Score=182, Evalue=2e-46,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=44.6078431372549, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787985, Length=235, Percent_Identity=28.0851063829787, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=43.4599156118143, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21358325, Length=222, Percent_Identity=44.1441441441441, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24655794, Length=223, Percent_Identity=43.9461883408072, Blast_Score=187, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 23713; Mature: 23713

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKTRPDTQSCVADIPDGATLLVGGFGGAGMPHELIEAVIARAPKDLTIISNNAGNGTT
CCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHH
GLAALLAAGLVKKVVCSFPRQADSFVFDKLYREGKLELELVPQGNLVERIRAGGAGIGAF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCCEE
FTPTGYGTPIAAGKETRQIDGRNYVLEYPLKADFALIKARRGDRWGNLTYRKTARNFGPV
ECCCCCCCCCCCCCCHHEECCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHCCHH
MATAATITVAQVEDIVPLGTLDPEDIVTPGVFVDRVVAIGTGAAQ
HHHHHHEEHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIDKTRPDTQSCVADIPDGATLLVGGFGGAGMPHELIEAVIARAPKDLTIISNNAGNGTT
CCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHH
GLAALLAAGLVKKVVCSFPRQADSFVFDKLYREGKLELELVPQGNLVERIRAGGAGIGAF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCCEE
FTPTGYGTPIAAGKETRQIDGRNYVLEYPLKADFALIKARRGDRWGNLTYRKTARNFGPV
ECCCCCCCCCCCCCCHHEECCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHCCHH
MATAATITVAQVEDIVPLGTLDPEDIVTPGVFVDRVVAIGTGAAQ
HHHHHHEEHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]