Click here to switch to the map view.

The map label for this gene is rnhA [H]

Identifier: 154245049

GI number: 154245049

Start: 1271552

End: 1272289

Strand: Reverse

Name: rnhA [H]

Synonym: Xaut_1101

Alternate gene names: 154245049

Gene position: 1272289-1271552 (Counterclockwise)

Preceding gene: 154245050

Following gene: 154245048

Centisome position: 23.97

GC content: 68.56

Gene sequence:

>738_bases
ATGATCGCCGCCCACACGGATGGCTCCTGCCTTGGCAATCCCGGCCCGGGCGGCTGGGCGGGTGTGATCCTCGACGCCGA
CGGCACCGCCCGCACCCTCACCGGCTTCGCGCCCGACACCACGAACAACCGCATGGAACTGACGGCCGCTCTCATGGCGC
TCGGGGCACTGCCCGCCGACGTTCCGTCCGTGCTGTTCTGCGATAGCGAATACGTCGTGAAGGGCTTGAACACTTGGCTG
GCGTCCCGGGAGCGGCGTGGCTGGAAGACCGCACAGGACAAGCCCGTCGCCAATGCCGACCTCTGGCGCCAGCTCAGCGC
GGCGAAGGTGGAACGGCCCCTCGCCGAAATCCGCTGGGTGCGCGGTCACGCCGGCAACACCATGAACGAGACCGTCGATC
GGCTGGCGCGAGCCGAAGCCGAGAAGGCCAAGCTCTCCGTGCGTCGCGGTGGTGGCGTACCCTCCCTCGAACCCGAAGCG
CCCGCTCCGTTCGGCCGCTTGGTAAGAACGGCGCGATGGCGAACGCAAAATCTCCCGTCGACGGTCTCCCCACGGAGGCC
GCCGGCACCTCCACCGACGCCCTGGTCGACATCGCCGACATCATCACCCGTGCTGACTGGCAAGTGCGGGTCCGGATCGA
TGAGGCCACGGTGCGCAGCTACGCTGGCATCATGCGCGGCGGTGGTGCCATGCCTCCCGTCTCCATCGCTCGGATCGACG
GAGCGCTCTACCTCGTAG

Upstream 100 bases:

>100_bases
CCCTCACCTCCTGGACGGTCTGTTCAGCTCTTCCCCCCGCCCTGGTGCTCTTCGGCCCCTACGGCCTCGCCGCCGTCATC
GCGCTGACCGGAGGCCCGGC

Downstream 100 bases:

>100_bases
ACGGCTGGCACCGTCTGGAGGCCGCCAAGCTCAACGGCGAGACCTTTATCGACGCTTCCGTCGCTGACATGAGCGAGAAG
GAGGCACGGTGGGCCGCCGC

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIAAHTDGSCLGNPGPGGWAGVILDADGTARTLTGFAPDTTNNRMELTAALMALGALPADVPSVLFCDSEYVVKGLNTWL
ASRERRGWKTAQDKPVANADLWRQLSAAKVERPLAEIRWVRGHAGNTMNETVDRLARAEAEKAKLSVRRGGGVPSLEPEA
PAPFGRLVRTARWRTQNLPSTVSPRRPPAPPPTPWSTSPTSSPVLTGKCGSGSMRPRCAATLASCAAVVPCLPSPSLGST
ERSTS

Sequences:

>Translated_245_residues
MIAAHTDGSCLGNPGPGGWAGVILDADGTARTLTGFAPDTTNNRMELTAALMALGALPADVPSVLFCDSEYVVKGLNTWL
ASRERRGWKTAQDKPVANADLWRQLSAAKVERPLAEIRWVRGHAGNTMNETVDRLARAEAEKAKLSVRRGGGVPSLEPEA
PAPFGRLVRTARWRTQNLPSTVSPRRPPAPPPTPWSTSPTSSPVLTGKCGSGSMRPRCAATLASCAAVVPCLPSPSLGST
ERSTS
>Mature_245_residues
MIAAHTDGSCLGNPGPGGWAGVILDADGTARTLTGFAPDTTNNRMELTAALMALGALPADVPSVLFCDSEYVVKGLNTWL
ASRERRGWKTAQDKPVANADLWRQLSAAKVERPLAEIRWVRGHAGNTMNETVDRLARAEAEKAKLSVRRGGGVPSLEPEA
PAPFGRLVRTARWRTQNLPSTVSPRRPPAPPPTPWSTSPTSSPVLTGKCGSGSMRPRCAATLASCAAVVPCLPSPSLGST
ERSTS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=139, Percent_Identity=49.6402877697842, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI115532542, Length=142, Percent_Identity=33.0985915492958, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 25830; Mature: 25830

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAHTDGSCLGNPGPGGWAGVILDADGTARTLTGFAPDTTNNRMELTAALMALGALPAD
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
VPSVLFCDSEYVVKGLNTWLASRERRGWKTAQDKPVANADLWRQLSAAKVERPLAEIRWV
CCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RGHAGNTMNETVDRLARAEAEKAKLSVRRGGGVPSLEPEAPAPFGRLVRTARWRTQNLPS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
TVSPRRPPAPPPTPWSTSPTSSPVLTGKCGSGSMRPRCAATLASCAAVVPCLPSPSLGST
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
ERSTS
CCCCC
>Mature Secondary Structure
MIAAHTDGSCLGNPGPGGWAGVILDADGTARTLTGFAPDTTNNRMELTAALMALGALPAD
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
VPSVLFCDSEYVVKGLNTWLASRERRGWKTAQDKPVANADLWRQLSAAKVERPLAEIRWV
CCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RGHAGNTMNETVDRLARAEAEKAKLSVRRGGGVPSLEPEAPAPFGRLVRTARWRTQNLPS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
TVSPRRPPAPPPTPWSTSPTSSPVLTGKCGSGSMRPRCAATLASCAAVVPCLPSPSLGST
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
ERSTS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA