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The map label for this gene is atoS [H]

Identifier: 154244983

GI number: 154244983

Start: 1186420

End: 1188165

Strand: Reverse

Name: atoS [H]

Synonym: Xaut_1033

Alternate gene names: 154244983

Gene position: 1188165-1186420 (Counterclockwise)

Preceding gene: 154244984

Following gene: 154244982

Centisome position: 22.38

GC content: 69.82

Gene sequence:

>1746_bases
ATGGCGCGACGGCGCGGCTCGCGTTGGCTGAACTGGTGGTCGCTGCTGCCCCTGCGGCTGCGGCTGACCCTTTATTTCGT
CATGGTCAGCGTGCCCCCGGTGCTGGTGGCGAGCTTCATCGCGGCCGAGGTCATCTCGGCGACGTTCGAGCGCAACGTGG
AGCAGTGGATCGGCGAGATCGCAAGCTTCATGGCCAATGAGGCGGCGGAAGGACGCGAGGAGGCCCAGCGCGCCACCGCC
ATCGTGGCCGCCGCCCTGTCGCGGGCCGGCACGGGCGGCGTCGAGCCCATCGAGCCGTTCGCCGATCTGCTCACCTCCGT
GGGCTATGATTTCGTGCGCCTCTACACTGCCGACGGCAAGGTGCTGTTCTCCACTGGCGACCTGGAGCTGATGCAGCCTT
TGCCGCTCAAGGCGGTCTCATCCATCTTCTTCGTCCGGCAGGACGGCCGCCGCGCCATGATGGTAGGTGCGATCCAGGCG
GTGCATATCGGCGAGCAGGCTGGCTTCCTGTTCGTCGCCAATCTCTTGGACGAACAATTCTTCACCGCGCCGCAGACCAT
CCGCTCCCTCGACCTGCACCTGATCGAGGTGACCGAGAGCGGCGAATTGCGCGATCTCGAGGCCCTGCATCGCGCCCCGC
TGCCGGTGCCGCCGGAGGCGCTGGCGGCGCTCACCGCCGGCGCACCTATCGCCATCCAGCGGCGCAGCTACGGGCTGGGG
CCGGCGGTGGCCTTCACTGCCCTGCGTGATGATGGCGGGCGCCTCGTGGGCATCATCGCCTGCCGGCTCAACGGCACGTC
GGCGACGTTCGAGCGCCTGGGCACCGTGTGGCTGTTCGTGGCCCTGGCGGCGGTGGCGGGTGCGCTGTCGCTGCTGGTGG
GCTTCTCCATCGCCCGGCGCATGAGCCGTCCCCTGCACGATCTCACCCGCGGCGTGCGGGCGGTGGCCGAGGGCAATTAC
GCCATCCGCGTGCGCGAGACCGGCGGCCGCGAGATCGAGGCGCTGGCCAGTGGCTTCAATGCCATGACCGAGCAGCTTCA
GACCCTGCGCGACCGGGAGGCGGCGCTGCGCCACCGCGCCCAGCTGGCGACGCTGGGGCAGGCGGCGGCGGTGATCGCCC
ACGAGATCCGCAATCCGCTCGGCATCATCAAGACCTCGGCGGAGCTGGTGCGCCGCAAGACCCCCATGGCGCCAAGCGAA
GACCGGCTGATGATGTTCGTCCTCGACGAGGTCCAGCGTATCGACCGGCTGGTGAAGGAGCTGCTGGACTATGCCCGGCC
ACCGCAATGCGCCGCCGTTCCGCTCGATCTCGTCACCTCTATCGTCCAGCCGGCCCTCGACTTCATGGCGCCGGAGCTGC
GCCGCCGCGACATCACCCTCGCCGCCCGCCTGCCGGACCATCCGGTGCCGATCCAGGGCGACAAGGACCTGCTCCACCAG
GCGCTCATGAACCTGCTCATCAACGCCATGGACGCCGCCGGCGACGGCGGCCATGTGATCGTGCGGGTGGGTCAGGAGGA
GGACTCGGCCGTGCTCCATGTGGAGGACAACGGCCCCGGTGTGCCGCAGGACGTGCGCGCCGCCCTGTTCGATCCCTTCG
TCACCACCAAGGTGAACGGCACCGGCCTCGGCCTTGCCACCGTGCGCTCGACGGCAGAGGCGCACGGCGGCGCGGTGAGC
CATGCCGACGCACCGGGCGGCGGCGCCATCTTCACCCTCCGCCTCCCCCTCGGCAAACAGGGCTGA

Upstream 100 bases:

>100_bases
GGCGCTCCAATGGCATCGCGCGCCCGCCAGCCTGAAACGCTGCGACGCCCCGCCGGCCCCGGCGAAGGCCAGCGCCGGGA
ACAAGAGGTCCTAGGGCATC

Downstream 100 bases:

>100_bases
TGCCGCACATGGCCGCGAAGATACTCATCGTCGACGACGAGGTCCGCCATGGGGAGGTGCTGGAGGCAGCCCTCGCCGAG
CGCGGCTTCGAGGCGACTTC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MARRRGSRWLNWWSLLPLRLRLTLYFVMVSVPPVLVASFIAAEVISATFERNVEQWIGEIASFMANEAAEGREEAQRATA
IVAAALSRAGTGGVEPIEPFADLLTSVGYDFVRLYTADGKVLFSTGDLELMQPLPLKAVSSIFFVRQDGRRAMMVGAIQA
VHIGEQAGFLFVANLLDEQFFTAPQTIRSLDLHLIEVTESGELRDLEALHRAPLPVPPEALAALTAGAPIAIQRRSYGLG
PAVAFTALRDDGGRLVGIIACRLNGTSATFERLGTVWLFVALAAVAGALSLLVGFSIARRMSRPLHDLTRGVRAVAEGNY
AIRVRETGGREIEALASGFNAMTEQLQTLRDREAALRHRAQLATLGQAAAVIAHEIRNPLGIIKTSAELVRRKTPMAPSE
DRLMMFVLDEVQRIDRLVKELLDYARPPQCAAVPLDLVTSIVQPALDFMAPELRRRDITLAARLPDHPVPIQGDKDLLHQ
ALMNLLINAMDAAGDGGHVIVRVGQEEDSAVLHVEDNGPGVPQDVRAALFDPFVTTKVNGTGLGLATVRSTAEAHGGAVS
HADAPGGGAIFTLRLPLGKQG

Sequences:

>Translated_581_residues
MARRRGSRWLNWWSLLPLRLRLTLYFVMVSVPPVLVASFIAAEVISATFERNVEQWIGEIASFMANEAAEGREEAQRATA
IVAAALSRAGTGGVEPIEPFADLLTSVGYDFVRLYTADGKVLFSTGDLELMQPLPLKAVSSIFFVRQDGRRAMMVGAIQA
VHIGEQAGFLFVANLLDEQFFTAPQTIRSLDLHLIEVTESGELRDLEALHRAPLPVPPEALAALTAGAPIAIQRRSYGLG
PAVAFTALRDDGGRLVGIIACRLNGTSATFERLGTVWLFVALAAVAGALSLLVGFSIARRMSRPLHDLTRGVRAVAEGNY
AIRVRETGGREIEALASGFNAMTEQLQTLRDREAALRHRAQLATLGQAAAVIAHEIRNPLGIIKTSAELVRRKTPMAPSE
DRLMMFVLDEVQRIDRLVKELLDYARPPQCAAVPLDLVTSIVQPALDFMAPELRRRDITLAARLPDHPVPIQGDKDLLHQ
ALMNLLINAMDAAGDGGHVIVRVGQEEDSAVLHVEDNGPGVPQDVRAALFDPFVTTKVNGTGLGLATVRSTAEAHGGAVS
HADAPGGGAIFTLRLPLGKQG
>Mature_580_residues
ARRRGSRWLNWWSLLPLRLRLTLYFVMVSVPPVLVASFIAAEVISATFERNVEQWIGEIASFMANEAAEGREEAQRATAI
VAAALSRAGTGGVEPIEPFADLLTSVGYDFVRLYTADGKVLFSTGDLELMQPLPLKAVSSIFFVRQDGRRAMMVGAIQAV
HIGEQAGFLFVANLLDEQFFTAPQTIRSLDLHLIEVTESGELRDLEALHRAPLPVPPEALAALTAGAPIAIQRRSYGLGP
AVAFTALRDDGGRLVGIIACRLNGTSATFERLGTVWLFVALAAVAGALSLLVGFSIARRMSRPLHDLTRGVRAVAEGNYA
IRVRETGGREIEALASGFNAMTEQLQTLRDREAALRHRAQLATLGQAAAVIAHEIRNPLGIIKTSAELVRRKTPMAPSED
RLMMFVLDEVQRIDRLVKELLDYARPPQCAAVPLDLVTSIVQPALDFMAPELRRRDITLAARLPDHPVPIQGDKDLLHQA
LMNLLINAMDAAGDGGHVIVRVGQEEDSAVLHVEDNGPGVPQDVRAALFDPFVTTKVNGTGLGLATVRSTAEAHGGAVSH
ADAPGGGAIFTLRLPLGKQG

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=262, Percent_Identity=35.8778625954198, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=36.2068965517241, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790346, Length=289, Percent_Identity=28.3737024221453, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081816, Length=323, Percent_Identity=28.7925696594427, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788393, Length=292, Percent_Identity=29.4520547945205, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=28.6219081272085, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789808, Length=307, Percent_Identity=25.0814332247557, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790300, Length=219, Percent_Identity=30.5936073059361, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=220, Percent_Identity=32.7272727272727, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=28.8617886178862, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=332, Percent_Identity=26.5060240963855, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=26.1467889908257, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=310, Percent_Identity=25.1612903225806, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=308, Percent_Identity=24.6753246753247, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=280, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI48994928, Length=221, Percent_Identity=28.5067873303167, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=370, Percent_Identity=20.5405405405405, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62658; Mature: 62527

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRRGSRWLNWWSLLPLRLRLTLYFVMVSVPPVLVASFIAAEVISATFERNVEQWIGEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASFMANEAAEGREEAQRATAIVAAALSRAGTGGVEPIEPFADLLTSVGYDFVRLYTADGK
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCE
VLFSTGDLELMQPLPLKAVSSIFFVRQDGRRAMMVGAIQAVHIGEQAGFLFVANLLDEQF
EEEECCCCHHCCCCCHHHHHHHHHEECCCCEEEHHHHHHHEEECCCCCHHHHHHHHHHHH
FTAPQTIRSLDLHLIEVTESGELRDLEALHRAPLPVPPEALAALTAGAPIAIQRRSYGLG
HCCHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCC
PAVAFTALRDDGGRLVGIIACRLNGTSATFERLGTVWLFVALAAVAGALSLLVGFSIARR
HHHHEEEEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSRPLHDLTRGVRAVAEGNYAIRVRETGGREIEALASGFNAMTEQLQTLRDREAALRHRA
HCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLATLGQAAAVIAHEIRNPLGIIKTSAELVRRKTPMAPSEDRLMMFVLDEVQRIDRLVKE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHH
LLDYARPPQCAAVPLDLVTSIVQPALDFMAPELRRRDITLAARLPDHPVPIQGDKDLLHQ
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHCCEEEEEECCCCCCCCCCCHHHHHH
ALMNLLINAMDAAGDGGHVIVRVGQEEDSAVLHVEDNGPGVPQDVRAALFDPFVTTKVNG
HHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCHHEEEECC
TGLGLATVRSTAEAHGGAVSHADAPGGGAIFTLRLPLGKQG
CCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
ARRRGSRWLNWWSLLPLRLRLTLYFVMVSVPPVLVASFIAAEVISATFERNVEQWIGEI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASFMANEAAEGREEAQRATAIVAAALSRAGTGGVEPIEPFADLLTSVGYDFVRLYTADGK
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCE
VLFSTGDLELMQPLPLKAVSSIFFVRQDGRRAMMVGAIQAVHIGEQAGFLFVANLLDEQF
EEEECCCCHHCCCCCHHHHHHHHHEECCCCEEEHHHHHHHEEECCCCCHHHHHHHHHHHH
FTAPQTIRSLDLHLIEVTESGELRDLEALHRAPLPVPPEALAALTAGAPIAIQRRSYGLG
HCCHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCC
PAVAFTALRDDGGRLVGIIACRLNGTSATFERLGTVWLFVALAAVAGALSLLVGFSIARR
HHHHEEEEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSRPLHDLTRGVRAVAEGNYAIRVRETGGREIEALASGFNAMTEQLQTLRDREAALRHRA
HCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLATLGQAAAVIAHEIRNPLGIIKTSAELVRRKTPMAPSEDRLMMFVLDEVQRIDRLVKE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHH
LLDYARPPQCAAVPLDLVTSIVQPALDFMAPELRRRDITLAARLPDHPVPIQGDKDLLHQ
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHCCEEEEEECCCCCCCCCCCHHHHHH
ALMNLLINAMDAAGDGGHVIVRVGQEEDSAVLHVEDNGPGVPQDVRAALFDPFVTTKVNG
HHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCHHEEEECC
TGLGLATVRSTAEAHGGAVSHADAPGGGAIFTLRLPLGKQG
CCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]