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The map label for this gene is gntR [H]

Identifier: 154244979

GI number: 154244979

Start: 1182355

End: 1183422

Strand: Direct

Name: gntR [H]

Synonym: Xaut_1029

Alternate gene names: 154244979

Gene position: 1182355-1183422 (Clockwise)

Preceding gene: 154244969

Following gene: 154244980

Centisome position: 22.27

GC content: 69.57

Gene sequence:

>1068_bases
ATGCGAGATGACGCGATCCGTGACGACGCGCTGGCGGGGCGCCGCGCGAGCGCAGGTCCGCACCTTGTCTCTCCCGCGGG
CTCGGGTGCGGGCGTCACCCTCACGGATGTGGCGCGCGAGGCCGGCGTCGGCGAGAGCACGGCTTCGCGGGTGCTGCGCA
GCCACGGTTCGTTTTCATCCAAGACACGCGCCAGCGTGCTGGAGGCGGCCGCCCGGCTCGGCTACGTGCCGAACCGCATC
GCGGGAACCCTCGCCTCCACCGGATCGAAGCTGGTGGGCATCATCGTGCCCTCGCTCGCCAATATCGTGTTTCCGGACCT
GCTGCGCGGCGCCAATTCGGTGCTCGGCAAGGCCGGCTTCCAGTCGGTCATCGGCGTCACCGACTATGATCTTGTGGGCG
AGGAAGCCCTCATCGCCTCGCTGCTCAGCTGGCGCCCGGCCGGGCTGCTGGTGGCGGGGCTGGAACACACGCCGCGGGCC
GACGCCATGCTGCGCGGCGCCGGCATCCGCATCATCGAGATGCTCGACACCGACGGGGCCGGCATCGACATGGTGGTGGG
CTTCTCCAACCGAGAGGCGGGCCGCGCTAGCGCGCGCCATCTCATCACCCGCGGTTATCGCCGGATCGGCTATGTGGGCC
ACGACCTGGCCCTCGACCTGCGCGCCGCCAAAAGGTTCGAGGGGTTCCGCTCCACGCTTGCCGAGGCCGGGCTCCAGGTG
GCAGGGCAAGTGATCGCGTCGGCGCCCTCGTCCATCGAGGCGGGGCGCGACGGGCTGGCGCGGATCCTGAGTGAGACCCG
CGATCTTGACGCCGTCTATTTCTCCAACGACGACATGGCCATCGGCGGCTATTTCCTCTGCCTGTCCAGGGGCATCGGCA
TTCCGGGCGAGCTGGCGCTGTTCGGCCACAACGGCCTTGAGGTCGCCCGCTGCGCGCCGCAGCCCCTGTCAACGATCCGC
ACCCCCCGCGTCGAGGTGGGCGAGGCCAGCGCACGGCTCATTTCATCGGATGGGCCGCCAGCCGTCGTCACCCTCGATTT
CGAGTTGATCGAGGGGGCGACCACTTAA

Upstream 100 bases:

>100_bases
CGGCAACAAACACGAAAACCCGACGCGCATTTGCCGCGCATCCGGAGTGCGCCTAACCGGGCAGGGGAGGGCAGGCGTGG
CCGACAAGGACGCCAGTTCG

Downstream 100 bases:

>100_bases
ATTCCGTCGGTTCGGACCCGGCATTTTCTTTCCGCGCCGGGCCGAGATCTTCCGTTCCCGCTTTGGAGCCCGCGCCTCAG
CATTGGGGCCGGGCCGAGGA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MRDDAIRDDALAGRRASAGPHLVSPAGSGAGVTLTDVAREAGVGESTASRVLRSHGSFSSKTRASVLEAAARLGYVPNRI
AGTLASTGSKLVGIIVPSLANIVFPDLLRGANSVLGKAGFQSVIGVTDYDLVGEEALIASLLSWRPAGLLVAGLEHTPRA
DAMLRGAGIRIIEMLDTDGAGIDMVVGFSNREAGRASARHLITRGYRRIGYVGHDLALDLRAAKRFEGFRSTLAEAGLQV
AGQVIASAPSSIEAGRDGLARILSETRDLDAVYFSNDDMAIGGYFLCLSRGIGIPGELALFGHNGLEVARCAPQPLSTIR
TPRVEVGEASARLISSDGPPAVVTLDFELIEGATT

Sequences:

>Translated_355_residues
MRDDAIRDDALAGRRASAGPHLVSPAGSGAGVTLTDVAREAGVGESTASRVLRSHGSFSSKTRASVLEAAARLGYVPNRI
AGTLASTGSKLVGIIVPSLANIVFPDLLRGANSVLGKAGFQSVIGVTDYDLVGEEALIASLLSWRPAGLLVAGLEHTPRA
DAMLRGAGIRIIEMLDTDGAGIDMVVGFSNREAGRASARHLITRGYRRIGYVGHDLALDLRAAKRFEGFRSTLAEAGLQV
AGQVIASAPSSIEAGRDGLARILSETRDLDAVYFSNDDMAIGGYFLCLSRGIGIPGELALFGHNGLEVARCAPQPLSTIR
TPRVEVGEASARLISSDGPPAVVTLDFELIEGATT
>Mature_355_residues
MRDDAIRDDALAGRRASAGPHLVSPAGSGAGVTLTDVAREAGVGESTASRVLRSHGSFSSKTRASVLEAAARLGYVPNRI
AGTLASTGSKLVGIIVPSLANIVFPDLLRGANSVLGKAGFQSVIGVTDYDLVGEEALIASLLSWRPAGLLVAGLEHTPRA
DAMLRGAGIRIIEMLDTDGAGIDMVVGFSNREAGRASARHLITRGYRRIGYVGHDLALDLRAAKRFEGFRSTLAEAGLQV
AGQVIASAPSSIEAGRDGLARILSETRDLDAVYFSNDDMAIGGYFLCLSRGIGIPGELALFGHNGLEVARCAPQPLSTIR
TPRVEVGEASARLISSDGPPAVVTLDFELIEGATT

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=326, Percent_Identity=33.4355828220859, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1790715, Length=329, Percent_Identity=31.306990881459, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1790194, Length=298, Percent_Identity=27.8523489932886, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790369, Length=303, Percent_Identity=25.0825082508251, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=28.8135593220339, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788474, Length=306, Percent_Identity=28.4313725490196, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787948, Length=326, Percent_Identity=26.0736196319018, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789068, Length=311, Percent_Identity=24.7588424437299, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786540, Length=305, Percent_Identity=27.8688524590164, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787906, Length=265, Percent_Identity=28.6792452830189, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=24.4648318042813, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36896; Mature: 36896

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDDAIRDDALAGRRASAGPHLVSPAGSGAGVTLTDVAREAGVGESTASRVLRSHGSFSS
CCCCCCCHHHHCCCCCCCCCCEECCCCCCCCEEHHHHHHHCCCCHHHHHHHHHHCCCCCH
KTRASVLEAAARLGYVPNRIAGTLASTGSKLVGIIVPSLANIVFPDLLRGANSVLGKAGF
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVIGVTDYDLVGEEALIASLLSWRPAGLLVAGLEHTPRADAMLRGAGIRIIEMLDTDGA
HHHHCCCCHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCEEEEEEECCCCC
GIDMVVGFSNREAGRASARHLITRGYRRIGYVGHDLALDLRAAKRFEGFRSTLAEAGLQV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQVIASAPSSIEAGRDGLARILSETRDLDAVYFSNDDMAIGGYFLCLSRGIGIPGELAL
HHHHHHCCCCHHHCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
FGHNGLEVARCAPQPLSTIRTPRVEVGEASARLISSDGPPAVVTLDFELIEGATT
EECCCCCEECCCCCCHHHHCCCCCCCCCHHHHEECCCCCCEEEEEEHEECCCCCC
>Mature Secondary Structure
MRDDAIRDDALAGRRASAGPHLVSPAGSGAGVTLTDVAREAGVGESTASRVLRSHGSFSS
CCCCCCCHHHHCCCCCCCCCCEECCCCCCCCEEHHHHHHHCCCCHHHHHHHHHHCCCCCH
KTRASVLEAAARLGYVPNRIAGTLASTGSKLVGIIVPSLANIVFPDLLRGANSVLGKAGF
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVIGVTDYDLVGEEALIASLLSWRPAGLLVAGLEHTPRADAMLRGAGIRIIEMLDTDGA
HHHHCCCCHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCEEEEEEECCCCC
GIDMVVGFSNREAGRASARHLITRGYRRIGYVGHDLALDLRAAKRFEGFRSTLAEAGLQV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQVIASAPSSIEAGRDGLARILSETRDLDAVYFSNDDMAIGGYFLCLSRGIGIPGELAL
HHHHHHCCCCHHHCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
FGHNGLEVARCAPQPLSTIRTPRVEVGEASARLISSDGPPAVVTLDFELIEGATT
EECCCCCEECCCCCCHHHHCCCCCCCCCHHHHEECCCCCCEEEEEEHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]