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The map label for this gene is ubiB [C]

Identifier: 154244953

GI number: 154244953

Start: 1122940

End: 1124682

Strand: Reverse

Name: ubiB [C]

Synonym: Xaut_1003

Alternate gene names: 154244953

Gene position: 1124682-1122940 (Counterclockwise)

Preceding gene: 154244954

Following gene: 154244951

Centisome position: 21.18

GC content: 69.13

Gene sequence:

>1743_bases
ATGCCCGAGGCGACGCAGTCCCCGGCAGCGCCCGCCCTGACCAACCAGCAGCGAGCCCGCGCGGTCCGGCGGCTGTTCCT
GCGCATCGCGCTCCACATCTTCTTCTGGGACATCGTGATGACGCGCGGGCCGCTGAAGCGGCTCCGCCGCGCGCCCGCTC
CGCGCTGGGCCGCCCTCGCCCGGCAATATCGCCGCGAGGCCGAGCGCTTGGGCGGCGTGCTCATCAAGCTCGGCCAGTAT
GTCAGCGCCCGCGTCGACCTCCTGCCCGAGGAGGTCACCCACGTGATGGCCGACCTGCGCGATGCGGTGCCCCCCGTGCC
GGGCCCGCAGATCATCGCGCAGATCGAAGAGGATTTTCTCCTCCCCATCACTGGCCTCTACCACAGCTTCGATGAGGTGC
CCATCGGCGCGGCGTCGCTCGGGCAGGCACACCGGGCGGTATTGCCGGAGGGCCAGCCGGTGGTGGTGAAGGTGCTGCGG
CCGGGCATCGATGCCATCGTCGCCAGCGACCTCGAAATCGTCGGCCAGTTCATCCGCCAGCTCAAGCGGCTGGAGAGCAT
CCGCCGCCGGGTGGACCTCGACCTTCTGGCCAGCGAGTTCACGGCGGTGACCTACCGTGAGCTGGACCTCGTCGCCGAGG
CCCGCAATTGCGAACGCTTCGCCCGCGAGTTCGCCCACGAACCCACCATCCACACGCCCACCATCTACTGGTCCCGCAGC
GGCCGGCGCACCCTGACCATGGAGGATGTCTCCTACTTCCCCATCCACGACGTGCTGGGCTTCGAGGCCGCCGGTATCGA
CCGCCGCCGCGTCGCCAGCAAGCTGATGGACTGCTACCTCGACCAGGTGTTCCGGCACGGTTTCGTTCACGCCGATCCGC
ACCCGGGCAATCTGTTCGTGCGGCCGCTGGCGGCGGACGGCGAGAGCGCGGCGAGCTGGCCGCCCTTCAGCCTCGCGTCG
GGGCGGGTGCACATTCCGCACGTGGCCAACCGGCCGTTCCAGGTGGTGTTCATCGATTTCGGCATGGCGGTGGAGATCCC
CGAGCGGCTGCGCCATTCGCTCACCACCTACGCCACCGGCATGGTGGCCCGCGACGCCTACACCATCGTCCAGTCCTATG
TGGAGGGCGACCTGCTCTTGCCCGACACCGACCTCGACGAGTTGGAGCGCATGACGGCGGCGCTGATCAACAAGTTTCCC
CACGCTCTGGTGGGTCAGGTGCGCAAGAAGGACCTGACGCCGTTCGCCGAGCTGTCGGAGGAATACCAGACCCTGCTCTA
CAACTCGCCCATGAAGATGAAGGCGGAGCTGTTGTTCGTGTTCCGCGCCATGGGCATCTGCTCGGGGACGGTGGCGGGCA
TCGATGCCGCTTTCGATCCCGCCGAGCGCTTCATGCCGCTGGCCCAGCGGCTGGTGGCGGACGAGTTGAAGCCGGATTCC
GACCGTCTGAAGCGCCTCATCTCGGCCACCGTCCGGCTGCCCATGCGGCTCGACAATCTGCTCACCACGCTGGAGCGCGG
CAAGCTGCGCATCCGCACCGACGGCGCCGACCGCCGCCGCGACGACATCCGCCAGCTCACCCGCGCGGCCAACCGGCTGG
GCGTCGCGGTGCTGGCCGGCAGCGCTATGATCTGCGCGGTGCTGCTGGGGCGGCAGGGGGAGATCGTCACCACCCCCACC
GGCCTCGCGGTCCTGGCCATCGCCGTGGTGGCGGCCGGGGTGCTGATCAAACAGCGCTCCTAG

Upstream 100 bases:

>100_bases
CCAAGGTGCCGTTCAATGATCGCGACCGGCGCCAGGACGGCGACATCGCCATGGTCAAGGAAATGATCCAGCGGCGCACC
CTGCCCCTGGACTTCAACTG

Downstream 100 bases:

>100_bases
AGCTTTTTCCGTTCGCCTCAGCTCAAGGAAGCCGCCGTGGGCTCTCGTGTTGATGCGTTTTCTGCGTGCGAACCGGTGTC
CACTTCGCTTGAAAACGCTT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MPEATQSPAAPALTNQQRARAVRRLFLRIALHIFFWDIVMTRGPLKRLRRAPAPRWAALARQYRREAERLGGVLIKLGQY
VSARVDLLPEEVTHVMADLRDAVPPVPGPQIIAQIEEDFLLPITGLYHSFDEVPIGAASLGQAHRAVLPEGQPVVVKVLR
PGIDAIVASDLEIVGQFIRQLKRLESIRRRVDLDLLASEFTAVTYRELDLVAEARNCERFAREFAHEPTIHTPTIYWSRS
GRRTLTMEDVSYFPIHDVLGFEAAGIDRRRVASKLMDCYLDQVFRHGFVHADPHPGNLFVRPLAADGESAASWPPFSLAS
GRVHIPHVANRPFQVVFIDFGMAVEIPERLRHSLTTYATGMVARDAYTIVQSYVEGDLLLPDTDLDELERMTAALINKFP
HALVGQVRKKDLTPFAELSEEYQTLLYNSPMKMKAELLFVFRAMGICSGTVAGIDAAFDPAERFMPLAQRLVADELKPDS
DRLKRLISATVRLPMRLDNLLTTLERGKLRIRTDGADRRRDDIRQLTRAANRLGVAVLAGSAMICAVLLGRQGEIVTTPT
GLAVLAIAVVAAGVLIKQRS

Sequences:

>Translated_580_residues
MPEATQSPAAPALTNQQRARAVRRLFLRIALHIFFWDIVMTRGPLKRLRRAPAPRWAALARQYRREAERLGGVLIKLGQY
VSARVDLLPEEVTHVMADLRDAVPPVPGPQIIAQIEEDFLLPITGLYHSFDEVPIGAASLGQAHRAVLPEGQPVVVKVLR
PGIDAIVASDLEIVGQFIRQLKRLESIRRRVDLDLLASEFTAVTYRELDLVAEARNCERFAREFAHEPTIHTPTIYWSRS
GRRTLTMEDVSYFPIHDVLGFEAAGIDRRRVASKLMDCYLDQVFRHGFVHADPHPGNLFVRPLAADGESAASWPPFSLAS
GRVHIPHVANRPFQVVFIDFGMAVEIPERLRHSLTTYATGMVARDAYTIVQSYVEGDLLLPDTDLDELERMTAALINKFP
HALVGQVRKKDLTPFAELSEEYQTLLYNSPMKMKAELLFVFRAMGICSGTVAGIDAAFDPAERFMPLAQRLVADELKPDS
DRLKRLISATVRLPMRLDNLLTTLERGKLRIRTDGADRRRDDIRQLTRAANRLGVAVLAGSAMICAVLLGRQGEIVTTPT
GLAVLAIAVVAAGVLIKQRS
>Mature_579_residues
PEATQSPAAPALTNQQRARAVRRLFLRIALHIFFWDIVMTRGPLKRLRRAPAPRWAALARQYRREAERLGGVLIKLGQYV
SARVDLLPEEVTHVMADLRDAVPPVPGPQIIAQIEEDFLLPITGLYHSFDEVPIGAASLGQAHRAVLPEGQPVVVKVLRP
GIDAIVASDLEIVGQFIRQLKRLESIRRRVDLDLLASEFTAVTYRELDLVAEARNCERFAREFAHEPTIHTPTIYWSRSG
RRTLTMEDVSYFPIHDVLGFEAAGIDRRRVASKLMDCYLDQVFRHGFVHADPHPGNLFVRPLAADGESAASWPPFSLASG
RVHIPHVANRPFQVVFIDFGMAVEIPERLRHSLTTYATGMVARDAYTIVQSYVEGDLLLPDTDLDELERMTAALINKFPH
ALVGQVRKKDLTPFAELSEEYQTLLYNSPMKMKAELLFVFRAMGICSGTVAGIDAAFDPAERFMPLAQRLVADELKPDSD
RLKRLISATVRLPMRLDNLLTTLERGKLRIRTDGADRRRDDIRQLTRAANRLGVAVLAGSAMICAVLLGRQGEIVTTPTG
LAVLAIAVVAAGVLIKQRS

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=238, Percent_Identity=34.453781512605, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI41393593, Length=295, Percent_Identity=29.1525423728814, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI217035081, Length=187, Percent_Identity=34.2245989304813, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI27363457, Length=230, Percent_Identity=24.7826086956522, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI217416386, Length=223, Percent_Identity=23.7668161434978, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI34147522, Length=236, Percent_Identity=24.5762711864407, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI2367309, Length=333, Percent_Identity=28.5285285285285, Blast_Score=142, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17559152, Length=315, Percent_Identity=27.9365079365079, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32565180, Length=245, Percent_Identity=27.3469387755102, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323282, Length=314, Percent_Identity=26.4331210191083, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325148, Length=482, Percent_Identity=21.7842323651452, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321319, Length=258, Percent_Identity=22.8682170542636, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24662575, Length=309, Percent_Identity=28.8025889967638, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI22024280, Length=311, Percent_Identity=28.9389067524116, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 64662; Mature: 64531

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEATQSPAAPALTNQQRARAVRRLFLRIALHIFFWDIVMTRGPLKRLRRAPAPRWAALA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHH
RQYRREAERLGGVLIKLGQYVSARVDLLPEEVTHVMADLRDAVPPVPGPQIIAQIEEDFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LPITGLYHSFDEVPIGAASLGQAHRAVLPEGQPVVVKVLRPGIDAIVASDLEIVGQFIRQ
CHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHH
LKRLESIRRRVDLDLLASEFTAVTYRELDLVAEARNCERFAREFAHEPTIHTPTIYWSRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
GRRTLTMEDVSYFPIHDVLGFEAAGIDRRRVASKLMDCYLDQVFRHGFVHADPHPGNLFV
CCEEEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
RPLAADGESAASWPPFSLASGRVHIPHVANRPFQVVFIDFGMAVEIPERLRHSLTTYATG
EEECCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEECCCEECCHHHHHHHHHHHHHH
MVARDAYTIVQSYVEGDLLLPDTDLDELERMTAALINKFPHALVGQVRKKDLTPFAELSE
HHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
EYQTLLYNSPMKMKAELLFVFRAMGICSGTVAGIDAAFDPAERFMPLAQRLVADELKPDS
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCH
DRLKRLISATVRLPMRLDNLLTTLERGKLRIRTDGADRRRDDIRQLTRAANRLGVAVLAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SAMICAVLLGRQGEIVTTPTGLAVLAIAVVAAGVLIKQRS
HHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PEATQSPAAPALTNQQRARAVRRLFLRIALHIFFWDIVMTRGPLKRLRRAPAPRWAALA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHH
RQYRREAERLGGVLIKLGQYVSARVDLLPEEVTHVMADLRDAVPPVPGPQIIAQIEEDFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LPITGLYHSFDEVPIGAASLGQAHRAVLPEGQPVVVKVLRPGIDAIVASDLEIVGQFIRQ
CHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHH
LKRLESIRRRVDLDLLASEFTAVTYRELDLVAEARNCERFAREFAHEPTIHTPTIYWSRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
GRRTLTMEDVSYFPIHDVLGFEAAGIDRRRVASKLMDCYLDQVFRHGFVHADPHPGNLFV
CCEEEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
RPLAADGESAASWPPFSLASGRVHIPHVANRPFQVVFIDFGMAVEIPERLRHSLTTYATG
EEECCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEECCCEECCHHHHHHHHHHHHHH
MVARDAYTIVQSYVEGDLLLPDTDLDELERMTAALINKFPHALVGQVRKKDLTPFAELSE
HHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
EYQTLLYNSPMKMKAELLFVFRAMGICSGTVAGIDAAFDPAERFMPLAQRLVADELKPDS
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCH
DRLKRLISATVRLPMRLDNLLTTLERGKLRIRTDGADRRRDDIRQLTRAANRLGVAVLAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
SAMICAVLLGRQGEIVTTPTGLAVLAIAVVAAGVLIKQRS
HHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]