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The map label for this gene is namA [H]

Identifier: 154244934

GI number: 154244934

Start: 1099575

End: 1100738

Strand: Direct

Name: namA [H]

Synonym: Xaut_0984

Alternate gene names: 154244934

Gene position: 1099575-1100738 (Clockwise)

Preceding gene: 154244932

Following gene: 154244935

Centisome position: 20.71

GC content: 68.9

Gene sequence:

>1164_bases
ATGGCTTCTCTTTTCAGCGAATTGCAAGTACGGGACGTGACCTTGCGGAACCGCATAGCGGTGTCGCCGATGACGCAGTT
TTCATCGCCGGACGGTCTCGTCACCGACTGGCACCTGGCCCATCTCGGGTCCAAGGCGGCGGGCGGCGCCGGCATGGTCA
TGGTGGAGCAGGTGGCGGTGGCGCCGGAAGGCCGCATGTCGACCACCTGCGCCGGCCTGTGGAACGATGAGCAGGGTGAG
GCGCTGGCGCGCATCGCGCGGTTCGTGCGGTCGGTCGGCTGCGTCCCCGGCATCCAGCTCGGCCATTCGGGCCGGCGCGG
TTGCGTGGAGCCGCCGTGGCTGGGCGGCGGCCATCTTCCCGCCGATCATCCCGATGCGTGGGAGATGATCGGCCCCTCCG
CGCTTCCGTTTGGCGGCGTCATGCATCGCACGCCGCGGGAAATGACGCGGGACGACATCGCTGCCATGGCCGGCGCCTAT
GCCGCGGCGGCGCGGCGGGCGCGCGAGGCCGGCTTCGAATGGCTGGAAATCCACGCCGCGCACGGCTTCCTGCTCTCGAG
CTTCTTCTCGCCGCTCTCCAATCATCGCACCGATGAATACGGCGGTGACTTTACCGGGCGCAGTCGTTTCCTCGTGGAGG
TGGTCGAGGCGGTGCGCGCCGAATGGCCGGAGCGGCTGCCGCTCTCCATGCGCTTCGGCGTCACCGAATTTGCGCCGGGC
AGCCAGACCATCGAGGATTCGGTGGCGCTGGCCCGCCTGCTGAAGCCGAAGGGCCTCGATCTCGTGGACGTGTCGTTCGG
CGGCAATTCGGGCCAGGCCCAGACGCCGTGGGAGGCCGAGGGCTTCATGGTGCCGGCCGCCGAGCGCATCCGCAGGGAGG
CGGACATCCTCACTGCCGCGAACTGGAACCTGGCCGACCCGCACTTCGCCGACGCCATCGTCCGCGAGGCGCGGGTGGAC
GTGGTGATGCTGGGCCGTCCCATGCTCGCCAATCCCCACTGGCCGGTCTACGCGGCCATGGTTCTGGGCCAGGAACGCCC
CTACGACCTGCTGCCGGTCCAGTTCAGCACCTGGCTCAACAAATACCAGCGCAGCCGCGTCAATGACGGCTTTGGCCACA
TCACCGGACGGGCCGCGGAGCCCGACGCCGCGGCTGCTGAATAA

Upstream 100 bases:

>100_bases
ATTCCTGCCTGCGTCGTGGGCATTCGAGGCGGGACGAAAGTCTTGGTACGACGATTATTCGGAATGTGACGCAGATCGAT
CCAGTGGGACGAGGTTGGAC

Downstream 100 bases:

>100_bases
GCGCCGCCCCAAAATCCCTTCTTCCGATCTTAATCATGGATTGAAGCTCATGTCCTCCATCGACACATCCTCCCTCGACG
CGCCCGCGCAGAATGCGGCG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MASLFSELQVRDVTLRNRIAVSPMTQFSSPDGLVTDWHLAHLGSKAAGGAGMVMVEQVAVAPEGRMSTTCAGLWNDEQGE
ALARIARFVRSVGCVPGIQLGHSGRRGCVEPPWLGGGHLPADHPDAWEMIGPSALPFGGVMHRTPREMTRDDIAAMAGAY
AAAARRAREAGFEWLEIHAAHGFLLSSFFSPLSNHRTDEYGGDFTGRSRFLVEVVEAVRAEWPERLPLSMRFGVTEFAPG
SQTIEDSVALARLLKPKGLDLVDVSFGGNSGQAQTPWEAEGFMVPAAERIRREADILTAANWNLADPHFADAIVREARVD
VVMLGRPMLANPHWPVYAAMVLGQERPYDLLPVQFSTWLNKYQRSRVNDGFGHITGRAAEPDAAAAE

Sequences:

>Translated_387_residues
MASLFSELQVRDVTLRNRIAVSPMTQFSSPDGLVTDWHLAHLGSKAAGGAGMVMVEQVAVAPEGRMSTTCAGLWNDEQGE
ALARIARFVRSVGCVPGIQLGHSGRRGCVEPPWLGGGHLPADHPDAWEMIGPSALPFGGVMHRTPREMTRDDIAAMAGAY
AAAARRAREAGFEWLEIHAAHGFLLSSFFSPLSNHRTDEYGGDFTGRSRFLVEVVEAVRAEWPERLPLSMRFGVTEFAPG
SQTIEDSVALARLLKPKGLDLVDVSFGGNSGQAQTPWEAEGFMVPAAERIRREADILTAANWNLADPHFADAIVREARVD
VVMLGRPMLANPHWPVYAAMVLGQERPYDLLPVQFSTWLNKYQRSRVNDGFGHITGRAAEPDAAAAE
>Mature_386_residues
ASLFSELQVRDVTLRNRIAVSPMTQFSSPDGLVTDWHLAHLGSKAAGGAGMVMVEQVAVAPEGRMSTTCAGLWNDEQGEA
LARIARFVRSVGCVPGIQLGHSGRRGCVEPPWLGGGHLPADHPDAWEMIGPSALPFGGVMHRTPREMTRDDIAAMAGAYA
AAARRAREAGFEWLEIHAAHGFLLSSFFSPLSNHRTDEYGGDFTGRSRFLVEVVEAVRAEWPERLPLSMRFGVTEFAPGS
QTIEDSVALARLLKPKGLDLVDVSFGGNSGQAQTPWEAEGFMVPAAERIRREADILTAANWNLADPHFADAIVREARVDV
VMLGRPMLANPHWPVYAAMVLGQERPYDLLPVQFSTWLNKYQRSRVNDGFGHITGRAAEPDAAAAE

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=355, Percent_Identity=27.6056338028169, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789463, Length=335, Percent_Identity=25.0746268656716, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=348, Percent_Identity=28.1609195402299, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=353, Percent_Identity=27.1954674220963, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=350, Percent_Identity=27.4285714285714, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=347, Percent_Identity=27.0893371757925, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=326, Percent_Identity=27.3006134969325, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=303, Percent_Identity=25.7425742574257, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=343, Percent_Identity=24.198250728863, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=233, Percent_Identity=27.4678111587983, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=238, Percent_Identity=26.890756302521, Blast_Score=90, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 42103; Mature: 41972

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLFSELQVRDVTLRNRIAVSPMTQFSSPDGLVTDWHLAHLGSKAAGGAGMVMVEQVAV
CCCHHHHHHHHHHHHHCEEEECCHHHCCCCCCCEECHHHHHCCCCCCCCCCHHHHHHHHH
APEGRMSTTCAGLWNDEQGEALARIARFVRSVGCVPGIQLGHSGRRGCVEPPWLGGGHLP
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCC
ADHPDAWEMIGPSALPFGGVMHRTPREMTRDDIAAMAGAYAAAARRAREAGFEWLEIHAA
CCCCCHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
HGFLLSSFFSPLSNHRTDEYGGDFTGRSRFLVEVVEAVRAEWPERLPLSMRFGVTEFAPG
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
SQTIEDSVALARLLKPKGLDLVDVSFGGNSGQAQTPWEAEGFMVPAAERIRREADILTAA
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEECCHHHHHHHHHHHEEEC
NWNLADPHFADAIVREARVDVVMLGRPMLANPHWPVYAAMVLGQERPYDLLPVQFSTWLN
CCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCEECCHHHHHHH
KYQRSRVNDGFGHITGRAAEPDAAAAE
HHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASLFSELQVRDVTLRNRIAVSPMTQFSSPDGLVTDWHLAHLGSKAAGGAGMVMVEQVAV
CCHHHHHHHHHHHHHCEEEECCHHHCCCCCCCEECHHHHHCCCCCCCCCCHHHHHHHHH
APEGRMSTTCAGLWNDEQGEALARIARFVRSVGCVPGIQLGHSGRRGCVEPPWLGGGHLP
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCC
ADHPDAWEMIGPSALPFGGVMHRTPREMTRDDIAAMAGAYAAAARRAREAGFEWLEIHAA
CCCCCHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
HGFLLSSFFSPLSNHRTDEYGGDFTGRSRFLVEVVEAVRAEWPERLPLSMRFGVTEFAPG
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
SQTIEDSVALARLLKPKGLDLVDVSFGGNSGQAQTPWEAEGFMVPAAERIRREADILTAA
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEECCHHHHHHHHHHHEEEC
NWNLADPHFADAIVREARVDVVMLGRPMLANPHWPVYAAMVLGQERPYDLLPVQFSTWLN
CCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCEECCHHHHHHH
KYQRSRVNDGFGHITGRAAEPDAAAAE
HHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA