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The map label for this gene is yugF [H]

Identifier: 154244906

GI number: 154244906

Start: 1075036

End: 1076049

Strand: Direct

Name: yugF [H]

Synonym: Xaut_0956

Alternate gene names: 154244906

Gene position: 1075036-1076049 (Clockwise)

Preceding gene: 154244905

Following gene: 154244909

Centisome position: 20.25

GC content: 67.06

Gene sequence:

>1014_bases
ATGCCTTCCCTGTCCCGCACGCTGATCGCCATCGGGGCGACGGCGCTTTGTCTCGGCCTGCCGCTTCCCGCCGCCCGATC
CGCCCCGCCGGCTCCCGCGCCGGGAGCCTCGCAGACCGTCCTTTCGCCGACGGTCCATTACCGGTCCAAGACCATCGACG
GCGTCGATGTCTTCTATCGCGAGGCGGGTCCCGCCGACGCACCGGTGCTCCTGCTGCTGCACGGCTTTCCCTCGTCCTCC
CACATGTTCCGCAACCTCATCCCGCTGCTGGCCGACCGCTACCGGGTGATCGCGCCCGACTATCCCGGCTTCGGCCATAG
CGCCGTGCCCGATCGCGCCCGGTTTTCATATGGATTTGCCGCCTATGCCGGCCTCGTCGACCGCCTCATGGGCGAACTGC
ATGCCAGTTCCTATGCCCTCTATGTGATGGATTATGGCGCGCCTGTCGGCTACCGGCTGGCCCTCATGCATCCCGAGCGG
GTGACCGCGCTGGTGGTGCAGAACGGCAATGCCTATGAGGAGGGCCTGAGCCCCTTCTGGACCCCGCTGAAGGCCTATTG
GGCGGACGGGGCACAGGCGAACCGCGATGCCCTGCGGGCCGGGCTGACGGCGGAGGCCACCCGCGCGCAATACGTCAACG
GCGTCGCCGACATCTCGCGGATCGATCCCGACACCTGGCTGGTGGACCAGGCCCTGCTCGACCGGCCGGGGGTGGACGAG
ATCATGCTCGACCTGTTCAAGGACTATGCGAGCAACGTCGCGCTCTATCCCGCCTTCCACGCCTTCTTCCGCGAGCGTCA
CCCGCCCACCCTCATCGTGTGGGGTGCCAGGGACGAGATCTTTCCCTCCGCCGGCGCGAAGGCCTATCTGAAGGACCTGC
CCAGGGCCGAACTTCATCTGCTGGACAGTGGGCATTTCGCGCTGGAGGACAAGGGCTCCGAAATCGCGGCGCTGATGCGC
GATTTCCTGTCCCGTTCCCTGCCGGTGAAAGGTGACAGGCCGACCGCACACTGA

Upstream 100 bases:

>100_bases
CGGCCGCCTGACGCCGGTCGCGCGCGCCCTCGCGCATCACCGGTCGCCGCGCCGGCCGATCCCGGCGTGGCGACCTTGCT
GCCCCTTGCGGAGTTTTCCG

Downstream 100 bases:

>100_bases
GCCACCCGAGTGGGCCGCCCGCATGGCTTGTGCGGGCGGCCTCGCGTCGCCGGAGTTGCCGGGCCGGTGTCACCAGCGCA
GCAGTCGCGGCCCCATGGCC

Product: alpha/beta hydrolase fold protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MPSLSRTLIAIGATALCLGLPLPAARSAPPAPAPGASQTVLSPTVHYRSKTIDGVDVFYREAGPADAPVLLLLHGFPSSS
HMFRNLIPLLADRYRVIAPDYPGFGHSAVPDRARFSYGFAAYAGLVDRLMGELHASSYALYVMDYGAPVGYRLALMHPER
VTALVVQNGNAYEEGLSPFWTPLKAYWADGAQANRDALRAGLTAEATRAQYVNGVADISRIDPDTWLVDQALLDRPGVDE
IMLDLFKDYASNVALYPAFHAFFRERHPPTLIVWGARDEIFPSAGAKAYLKDLPRAELHLLDSGHFALEDKGSEIAALMR
DFLSRSLPVKGDRPTAH

Sequences:

>Translated_337_residues
MPSLSRTLIAIGATALCLGLPLPAARSAPPAPAPGASQTVLSPTVHYRSKTIDGVDVFYREAGPADAPVLLLLHGFPSSS
HMFRNLIPLLADRYRVIAPDYPGFGHSAVPDRARFSYGFAAYAGLVDRLMGELHASSYALYVMDYGAPVGYRLALMHPER
VTALVVQNGNAYEEGLSPFWTPLKAYWADGAQANRDALRAGLTAEATRAQYVNGVADISRIDPDTWLVDQALLDRPGVDE
IMLDLFKDYASNVALYPAFHAFFRERHPPTLIVWGARDEIFPSAGAKAYLKDLPRAELHLLDSGHFALEDKGSEIAALMR
DFLSRSLPVKGDRPTAH
>Mature_336_residues
PSLSRTLIAIGATALCLGLPLPAARSAPPAPAPGASQTVLSPTVHYRSKTIDGVDVFYREAGPADAPVLLLLHGFPSSSH
MFRNLIPLLADRYRVIAPDYPGFGHSAVPDRARFSYGFAAYAGLVDRLMGELHASSYALYVMDYGAPVGYRLALMHPERV
TALVVQNGNAYEEGLSPFWTPLKAYWADGAQANRDALRAGLTAEATRAQYVNGVADISRIDPDTWLVDQALLDRPGVDEI
MLDLFKDYASNVALYPAFHAFFRERHPPTLIVWGARDEIFPSAGAKAYLKDLPRAELHLLDSGHFALEDKGSEIAALMRD
FLSRSLPVKGDRPTAH

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324392, Length=283, Percent_Identity=45.2296819787986, Blast_Score=248, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 36727; Mature: 36596

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLSRTLIAIGATALCLGLPLPAARSAPPAPAPGASQTVLSPTVHYRSKTIDGVDVFYR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCHHHHHHCCCCHHHHHHH
EAGPADAPVLLLLHGFPSSSHMFRNLIPLLADRYRVIAPDYPGFGHSAVPDRARFSYGFA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHH
AYAGLVDRLMGELHASSYALYVMDYGAPVGYRLALMHPERVTALVVQNGNAYEEGLSPFW
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCHHHCCCHHH
TPLKAYWADGAQANRDALRAGLTAEATRAQYVNGVADISRIDPDTWLVDQALLDRPGVDE
HHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
IMLDLFKDYASNVALYPAFHAFFRERHPPTLIVWGARDEIFPSAGAKAYLKDLPRAELHL
HHHHHHHHHHCCEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCEEE
LDSGHFALEDKGSEIAALMRDFLSRSLPVKGDRPTAH
ECCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PSLSRTLIAIGATALCLGLPLPAARSAPPAPAPGASQTVLSPTVHYRSKTIDGVDVFYR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCHHHHHHCCCCHHHHHHH
EAGPADAPVLLLLHGFPSSSHMFRNLIPLLADRYRVIAPDYPGFGHSAVPDRARFSYGFA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHH
AYAGLVDRLMGELHASSYALYVMDYGAPVGYRLALMHPERVTALVVQNGNAYEEGLSPFW
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCHHHCCCHHH
TPLKAYWADGAQANRDALRAGLTAEATRAQYVNGVADISRIDPDTWLVDQALLDRPGVDE
HHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
IMLDLFKDYASNVALYPAFHAFFRERHPPTLIVWGARDEIFPSAGAKAYLKDLPRAELHL
HHHHHHHHHHCCEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCEEE
LDSGHFALEDKGSEIAALMRDFLSRSLPVKGDRPTAH
ECCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]