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The map label for this gene is paaK [H]

Identifier: 154244851

GI number: 154244851

Start: 1003322

End: 1004659

Strand: Reverse

Name: paaK [H]

Synonym: Xaut_0901

Alternate gene names: 154244851

Gene position: 1004659-1003322 (Counterclockwise)

Preceding gene: 154244852

Following gene: 154244843

Centisome position: 18.92

GC content: 67.79

Gene sequence:

>1338_bases
ATGAACATGGCTCTGCCGGCGGTTTCCTTTGGCCGGACCTTCGAGGCCGGCCTTGATACAGCGGAACGGGCATCGCGGGA
CGAAATCATGTCCCTCCAGCGCGAGCGTCTCGCTTGGTCGCTGCGCCACGCCTATGAGAACGTGCCGTTCTACCGCAGGA
AGTTCGACGAGGCGGGGGTGCACCCCTCCGACCTGCGCGACCTATCGGACCTCGCCAAGTTCCCCTTCACGGTGAAGACC
GACCTGCGCGACAACTACCCCTTCGGCCTGTTCGCGGTGCCGCGCGAGAAGCTGCTGCGGGTGCACGGCTCCTCCGGCAC
CACGGGCAAGCCCATCGTGGTGGGCTATACCCGCGCCGACATCGACATGTGGGCCGACGTGATGGCCCGCTCCATCCGCG
CGGCCGGGGTGCGGCCGGGCATGATGGTGCACGTGGCCTATGGCTACGGCCTGTTCACCGGCGGCCTGGGCGCCCATTAC
GGCGTGGAGCGGCTCGGCTGCACCGTGGTGCCCATGTCCGGCGGCATGACCGAGCGTCAGGTGCAGCTCATCCACGACTT
CAAGCCAGACGCCATCATGGTGACGCCCAGCTACATGCTGGCGCTGCTGGACGGCTTCGCCAAGGCGGGGCTGGACCCGC
GCGCCTCCTCGCTGAAGTACGGCATCTTCGGCGCCGAGCCCTGGACCAACGCCATGCGCGAGGAGATCGAGCGCGACTTC
GCCATCGACGCCACCGACATCTACGGCCTCTCCGAGGTCATCGGCCCCGGCGTGGCGCAGGAATGCGTGGAGACCAAGGA
CGGCCTGCACATCTGGGAAGACCACTTCCTGCCGGAGGTGATCGACCCCATCACCGGCGAGGTGCTGCCGGACGGGGAGA
AGGGCGAGCTGGTGTTCACCTCCCTCACCAAGGAGGCGTTCCCGATCATCCGCTACCGCACCCGCGACCTCACCCGCCTT
CTGCCCGGCACGGCGCGGCCCGGCATGCGGCGCATGGAGAAGGTCACCGGCCGTTCGGACGACATGATCATCCTGCGGGG
GGTGAACGTGTTCCCCACCCAGATCGAGGAGATCCTGCTCTCCATCGAGACCTGCTCTGGCCACTACCAGCTGGAGCTGA
CCCGCGAGGGCCGCATGGACGAGATGACCGTGCATGCGGAGATCCGCGAGGAGGCCCAGGGCAGCACCGACATTGAGGCC
TGCGCGGCACACATCCTCGCCCGCATCAAGGACACGGTGGGCATCACCACCCGCATCGAGCTGCACGAGCCCGGCGGCAT
CGAGCGCACCGCCACCGGCAAGGCCAAGCGCATCATAGACCGCCGCCCCAAGGGGTGA

Upstream 100 bases:

>100_bases
TCGCGGGCATTCTCGCACCATCGGCGGGGCGTTGATCGCCCCGCCCCCAAGCGCGCCGGAGAGCCGCGACCACACGACCA
CAGCTTGAGTGGAGGAGACG

Downstream 100 bases:

>100_bases
GCTTTCCAGGATCCTCCCGACGGCGGGTTCGCCCGCCGTCACCCCCAGAAGAAAAAGGCCCGGCGCAAGCCGGGCCTTTT
TCTTTGCAGCCAAGAGACGG

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNMALPAVSFGRTFEAGLDTAERASRDEIMSLQRERLAWSLRHAYENVPFYRRKFDEAGVHPSDLRDLSDLAKFPFTVKT
DLRDNYPFGLFAVPREKLLRVHGSSGTTGKPIVVGYTRADIDMWADVMARSIRAAGVRPGMMVHVAYGYGLFTGGLGAHY
GVERLGCTVVPMSGGMTERQVQLIHDFKPDAIMVTPSYMLALLDGFAKAGLDPRASSLKYGIFGAEPWTNAMREEIERDF
AIDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFLPEVIDPITGEVLPDGEKGELVFTSLTKEAFPIIRYRTRDLTRL
LPGTARPGMRRMEKVTGRSDDMIILRGVNVFPTQIEEILLSIETCSGHYQLELTREGRMDEMTVHAEIREEAQGSTDIEA
CAAHILARIKDTVGITTRIELHEPGGIERTATGKAKRIIDRRPKG

Sequences:

>Translated_445_residues
MNMALPAVSFGRTFEAGLDTAERASRDEIMSLQRERLAWSLRHAYENVPFYRRKFDEAGVHPSDLRDLSDLAKFPFTVKT
DLRDNYPFGLFAVPREKLLRVHGSSGTTGKPIVVGYTRADIDMWADVMARSIRAAGVRPGMMVHVAYGYGLFTGGLGAHY
GVERLGCTVVPMSGGMTERQVQLIHDFKPDAIMVTPSYMLALLDGFAKAGLDPRASSLKYGIFGAEPWTNAMREEIERDF
AIDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFLPEVIDPITGEVLPDGEKGELVFTSLTKEAFPIIRYRTRDLTRL
LPGTARPGMRRMEKVTGRSDDMIILRGVNVFPTQIEEILLSIETCSGHYQLELTREGRMDEMTVHAEIREEAQGSTDIEA
CAAHILARIKDTVGITTRIELHEPGGIERTATGKAKRIIDRRPKG
>Mature_445_residues
MNMALPAVSFGRTFEAGLDTAERASRDEIMSLQRERLAWSLRHAYENVPFYRRKFDEAGVHPSDLRDLSDLAKFPFTVKT
DLRDNYPFGLFAVPREKLLRVHGSSGTTGKPIVVGYTRADIDMWADVMARSIRAAGVRPGMMVHVAYGYGLFTGGLGAHY
GVERLGCTVVPMSGGMTERQVQLIHDFKPDAIMVTPSYMLALLDGFAKAGLDPRASSLKYGIFGAEPWTNAMREEIERDF
AIDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFLPEVIDPITGEVLPDGEKGELVFTSLTKEAFPIIRYRTRDLTRL
LPGTARPGMRRMEKVTGRSDDMIILRGVNVFPTQIEEILLSIETCSGHYQLELTREGRMDEMTVHAEIREEAQGSTDIEA
CAAHILARIKDTVGITTRIELHEPGGIERTATGKAKRIIDRRPKG

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=428, Percent_Identity=61.9158878504673, Blast_Score=541, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49513; Mature: 49513

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMALPAVSFGRTFEAGLDTAERASRDEIMSLQRERLAWSLRHAYENVPFYRRKFDEAGV
CCCCCCCCCCCCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
HPSDLRDLSDLAKFPFTVKTDLRDNYPFGLFAVPREKLLRVHGSSGTTGKPIVVGYTRAD
CHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHEEECCCCCCCCCEEEEEECCC
IDMWADVMARSIRAAGVRPGMMVHVAYGYGLFTGGLGAHYGVERLGCTVVPMSGGMTERQ
HHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCCCCHHCCHHHHCEEEEECCCCCCHHH
VQLIHDFKPDAIMVTPSYMLALLDGFAKAGLDPRASSLKYGIFGAEPWTNAMREEIERDF
HHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
AIDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFLPEVIDPITGEVLPDGEKGELVFT
CCCCHHHCCHHHHHCCCHHHHHHHCCCCCEEHHHCCCHHHHCCCCCCCCCCCCCCCEEEE
SLTKEAFPIIRYRTRDLTRLLPGTARPGMRRMEKVTGRSDDMIILRGVNVFPTQIEEILL
EHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
SIETCSGHYQLELTREGRMDEMTVHAEIREEAQGSTDIEACAAHILARIKDTVGITTRIE
HHHCCCCEEEEEEECCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEE
LHEPGGIERTATGKAKRIIDRRPKG
EECCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MNMALPAVSFGRTFEAGLDTAERASRDEIMSLQRERLAWSLRHAYENVPFYRRKFDEAGV
CCCCCCCCCCCCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
HPSDLRDLSDLAKFPFTVKTDLRDNYPFGLFAVPREKLLRVHGSSGTTGKPIVVGYTRAD
CHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHEEECCCCCCCCCEEEEEECCC
IDMWADVMARSIRAAGVRPGMMVHVAYGYGLFTGGLGAHYGVERLGCTVVPMSGGMTERQ
HHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCCCCHHCCHHHHCEEEEECCCCCCHHH
VQLIHDFKPDAIMVTPSYMLALLDGFAKAGLDPRASSLKYGIFGAEPWTNAMREEIERDF
HHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
AIDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFLPEVIDPITGEVLPDGEKGELVFT
CCCCHHHCCHHHHHCCCHHHHHHHCCCCCEEHHHCCCHHHHCCCCCCCCCCCCCCCEEEE
SLTKEAFPIIRYRTRDLTRLLPGTARPGMRRMEKVTGRSDDMIILRGVNVFPTQIEEILL
EHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
SIETCSGHYQLELTREGRMDEMTVHAEIREEAQGSTDIEACAAHILARIKDTVGITTRIE
HHHCCCCEEEEEEECCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEE
LHEPGGIERTATGKAKRIIDRRPKG
EECCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]