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The map label for this gene is guaA [H]

Identifier: 154244838

GI number: 154244838

Start: 991446

End: 992201

Strand: Reverse

Name: guaA [H]

Synonym: Xaut_0888

Alternate gene names: 154244838

Gene position: 992201-991446 (Counterclockwise)

Preceding gene: 154244839

Following gene: 154244832

Centisome position: 18.69

GC content: 68.39

Gene sequence:

>756_bases
ATGGGCAAGCTTAAGGACCGCGGCATGAAGATCGGCATCCTGCAAACCGGGCGCGCGCCGGAGGATCTGCACGAGCAGCA
CGGCGACTACGACGCCATGTTCCGGCGCCTGCTGGCCGGGCGGGGGTTCGAGTTCGTCACCTATCCGGTGCTCGACGGCG
TCTTCCCTGACAGCGTGAACGATGCCGAGGGCTGGCTGATCACCGGCTCGCGGTTCGGCGTCTACGAGCCCCATCCGTGG
ATCGCGCCTCTGGAAGACTTCCTGCGCCGCGCCTATGCGGCCGGCGTACCTCTGGTCGGCATCTGCTTCGGCCACCAGAT
CTTGGCGCAGGCCCTGGGCGGCAAGGTGGAGAAATTCGCCGGCGGCTGGTCCGTGGGCGTGGAGCGCTATGCGGTGGAAG
GCCTGCTGGACGACGCCCGCCTCGTGGCGTGGCACCAGGACCAGGTGGTGGAGAAGCCGGCCGACGCCGAGGTCATCGCC
ACCTCGCCCTTCTGCCGGTTCGCGGCGCTGGCCTATGGCGACAGGGCGCTGTCGTTCCAGCCCCATCCGGAATTCACCCC
GGCCTTCGGCGCCGACCTGCTGAAGGCGCGCGGCAAGGCGCTGCCGGAGGAACTTGCCGCCAAGGCCGCCCAAAGCCTTG
AGGGCGAAACCTCCACGCCTGCCATCGCCGACATGATCGAAGCCTTCCTGCGGCGCGGGCAGGTGGGCAAGACTGTGCCT
GAGGCCGAAGCCGAAGCTCAGACCGTGAAGCCGTAA

Upstream 100 bases:

>100_bases
GCGCAAGCGGATCGGCGTGGATGCCCGGGACAAGCCCGGGCATGATGGGGTGATCGCGCTTATGCCCATTTTAAATTTCA
AACCGGTCTCTAAATAGGCA

Downstream 100 bases:

>100_bases
AGCGCCCACTCGGCATCGGACACTTCCAGCGCGAGGCGCAGCCATTCCGCGCGCTTGATGGCGGCGAAGCTGTGGTGTAG
CTCCGCCCCCAGCGCCTGCT

Product: glutamine amidotransferase class-I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MGKLKDRGMKIGILQTGRAPEDLHEQHGDYDAMFRRLLAGRGFEFVTYPVLDGVFPDSVNDAEGWLITGSRFGVYEPHPW
IAPLEDFLRRAYAAGVPLVGICFGHQILAQALGGKVEKFAGGWSVGVERYAVEGLLDDARLVAWHQDQVVEKPADAEVIA
TSPFCRFAALAYGDRALSFQPHPEFTPAFGADLLKARGKALPEELAAKAAQSLEGETSTPAIADMIEAFLRRGQVGKTVP
EAEAEAQTVKP

Sequences:

>Translated_251_residues
MGKLKDRGMKIGILQTGRAPEDLHEQHGDYDAMFRRLLAGRGFEFVTYPVLDGVFPDSVNDAEGWLITGSRFGVYEPHPW
IAPLEDFLRRAYAAGVPLVGICFGHQILAQALGGKVEKFAGGWSVGVERYAVEGLLDDARLVAWHQDQVVEKPADAEVIA
TSPFCRFAALAYGDRALSFQPHPEFTPAFGADLLKARGKALPEELAAKAAQSLEGETSTPAIADMIEAFLRRGQVGKTVP
EAEAEAQTVKP
>Mature_250_residues
GKLKDRGMKIGILQTGRAPEDLHEQHGDYDAMFRRLLAGRGFEFVTYPVLDGVFPDSVNDAEGWLITGSRFGVYEPHPWI
APLEDFLRRAYAAGVPLVGICFGHQILAQALGGKVEKFAGGWSVGVERYAVEGLLDDARLVAWHQDQVVEKPADAEVIAT
SPFCRFAALAYGDRALSFQPHPEFTPAFGADLLKARGKALPEELAAKAAQSLEGETSTPAIADMIEAFLRRGQVGKTVPE
AEAEAQTVKP

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323155, Length=206, Percent_Identity=28.6407766990291, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 27263; Mature: 27132

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLKDRGMKIGILQTGRAPEDLHEQHGDYDAMFRRLLAGRGFEFVTYPVLDGVFPDSVN
CCCCCCCCEEEEEEECCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCC
DAEGWLITGSRFGVYEPHPWIAPLEDFLRRAYAAGVPLVGICFGHQILAQALGGKVEKFA
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHC
GGWSVGVERYAVEGLLDDARLVAWHQDQVVEKPADAEVIATSPFCRFAALAYGDRALSFQ
CCHHHHHHHHHHHHHHCCHHHEEECHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
PHPEFTPAFGADLLKARGKALPEELAAKAAQSLEGETSTPAIADMIEAFLRRGQVGKTVP
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCC
EAEAEAQTVKP
CCCCCCCCCCC
>Mature Secondary Structure 
GKLKDRGMKIGILQTGRAPEDLHEQHGDYDAMFRRLLAGRGFEFVTYPVLDGVFPDSVN
CCCCCCCEEEEEEECCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCC
DAEGWLITGSRFGVYEPHPWIAPLEDFLRRAYAAGVPLVGICFGHQILAQALGGKVEKFA
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHC
GGWSVGVERYAVEGLLDDARLVAWHQDQVVEKPADAEVIATSPFCRFAALAYGDRALSFQ
CCHHHHHHHHHHHHHHCCHHHEEECHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
PHPEFTPAFGADLLKARGKALPEELAAKAAQSLEGETSTPAIADMIEAFLRRGQVGKTVP
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCC
EAEAEAQTVKP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA