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The map label for this gene is alsR [H]

Identifier: 154244689

GI number: 154244689

Start: 825822

End: 826766

Strand: Direct

Name: alsR [H]

Synonym: Xaut_0738

Alternate gene names: 154244689

Gene position: 825822-826766 (Clockwise)

Preceding gene: 154244688

Following gene: 154244718

Centisome position: 15.56

GC content: 60.95

Gene sequence:

>945_bases
ATGCGCGTCCGAGACCTCGGAATGTTACCGGTTGAGCTCAAGCATCTCCGCTATGCCGATGCGGCGTCGCAGCACGGCAG
CTTCCGCAAGGCGGCCGACGCACTTGGGCTCAAGCAATCAAATCTCAGCCGCAGAATCCGAACTCTTGAGGAGTGCCTCG
GCTACCGATTGTTCGAACGGACCAATGGGGGCGTACAGCCGACACCTATGGGGCGCGACTTTCTTCAAGGCGCACGGCGC
GTTCTCGATGATGTCCAAGCGATTGTGGATGCCGCAGATGCAGTGGCGCGGGGCGCGGCCGGACAACTTCGGCTCGGGTT
CTATACATCGCTCTCGGCCGGGAATCTGCGCAGCACGCTGCTCGACTATGCACGCCGTTTTCCGCAAGTGCGCATCAGCG
TGGTTGAGGACGAGCGATGTCGTTTGTGCGCCGGCCTGCGAAACGGGAAAATCGACATTGCGATCGTCACTGGTGAGCCG
ACTGCCGAAGGTGGCACGTCGATGGCGCTTTGGAGCGAACGGATCCTGATCGCACTTCCGGAAGCCCATGAACTTGCGGC
CAAAGAGGTCCTCAATTGGGGCGACTTGAAGCGCGAACGCTTCGTGCTGAGCACGCGCGACCCCGGCCCCGAGATCGAAT
CCATCCTGATCGCGAAGCTGGTTACACCGGGAGAGTCACTCAACATCGATCATCACGATGTCAACGCGGAGAGCCTGAAG
AGCCTGGTCAGTGCGGGACACGGCATCACCGTGGTCTGCGAGTCCTGCATGGGGTCTGTCCCGCCTGGGATGGTGTTCCG
CGAGACACGGGACGGCAATGGATCGACGCGTGTTGGCTTTTGTGCCTATTGGATGCCAGGCAACGAGAACCCGGCGCTGC
GGAATTTCATTCAGTTGCTGGAAGAGCGCTGCCCACCGTTGGGTGTGCGGCTGAACGGCGTTTAG

Upstream 100 bases:

>100_bases
CGCAGGTCAAGCTGCCTGTCTCGCGTTGATGCCCGCTTGGGCTGCGGGAGTTCTGTTTGCCAACCGAGCAGCGGGCGGCA
GATAACATCGCGACCGTGAC

Downstream 100 bases:

>100_bases
CGGATCGCGCAGGTGGTAGCGAAAGACACATGTATCGCTTCAATTGCGTGCTTGTGCATGAAATCCTGCGCTCGTTATAG
GCGTTATGTCCCTGCGTGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRVRDLGMLPVELKHLRYADAASQHGSFRKAADALGLKQSNLSRRIRTLEECLGYRLFERTNGGVQPTPMGRDFLQGARR
VLDDVQAIVDAADAVARGAAGQLRLGFYTSLSAGNLRSTLLDYARRFPQVRISVVEDERCRLCAGLRNGKIDIAIVTGEP
TAEGGTSMALWSERILIALPEAHELAAKEVLNWGDLKRERFVLSTRDPGPEIESILIAKLVTPGESLNIDHHDVNAESLK
SLVSAGHGITVVCESCMGSVPPGMVFRETRDGNGSTRVGFCAYWMPGNENPALRNFIQLLEERCPPLGVRLNGV

Sequences:

>Translated_314_residues
MRVRDLGMLPVELKHLRYADAASQHGSFRKAADALGLKQSNLSRRIRTLEECLGYRLFERTNGGVQPTPMGRDFLQGARR
VLDDVQAIVDAADAVARGAAGQLRLGFYTSLSAGNLRSTLLDYARRFPQVRISVVEDERCRLCAGLRNGKIDIAIVTGEP
TAEGGTSMALWSERILIALPEAHELAAKEVLNWGDLKRERFVLSTRDPGPEIESILIAKLVTPGESLNIDHHDVNAESLK
SLVSAGHGITVVCESCMGSVPPGMVFRETRDGNGSTRVGFCAYWMPGNENPALRNFIQLLEERCPPLGVRLNGV
>Mature_314_residues
MRVRDLGMLPVELKHLRYADAASQHGSFRKAADALGLKQSNLSRRIRTLEECLGYRLFERTNGGVQPTPMGRDFLQGARR
VLDDVQAIVDAADAVARGAAGQLRLGFYTSLSAGNLRSTLLDYARRFPQVRISVVEDERCRLCAGLRNGKIDIAIVTGEP
TAEGGTSMALWSERILIALPEAHELAAKEVLNWGDLKRERFVLSTRDPGPEIESILIAKLVTPGESLNIDHHDVNAESLK
SLVSAGHGITVVCESCMGSVPPGMVFRETRDGNGSTRVGFCAYWMPGNENPALRNFIQLLEERCPPLGVRLNGV

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=27.6450511945392, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787879, Length=295, Percent_Identity=28.135593220339, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790399, Length=262, Percent_Identity=27.8625954198473, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI2367136, Length=263, Percent_Identity=28.8973384030418, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789204, Length=249, Percent_Identity=28.5140562248996, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787806, Length=294, Percent_Identity=25.8503401360544, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI157672245, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788297, Length=168, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081904, Length=148, Percent_Identity=33.7837837837838, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=29.2517006802721, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787949, Length=306, Percent_Identity=25.4901960784314, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788748, Length=240, Percent_Identity=24.1666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=148, Percent_Identity=25.6756756756757, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787530, Length=304, Percent_Identity=23.6842105263158, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787128, Length=118, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786508, Length=146, Percent_Identity=29.4520547945205, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34374; Mature: 34374

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRDLGMLPVELKHLRYADAASQHGSFRKAADALGLKQSNLSRRIRTLEECLGYRLFER
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHH
TNGGVQPTPMGRDFLQGARRVLDDVQAIVDAADAVARGAAGQLRLGFYTSLSAGNLRSTL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHH
LDYARRFPQVRISVVEDERCRLCAGLRNGKIDIAIVTGEPTAEGGTSMALWSERILIALP
HHHHHHCCCEEEEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEECC
EAHELAAKEVLNWGDLKRERFVLSTRDPGPEIESILIAKLVTPGESLNIDHHDVNAESLK
CHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
SLVSAGHGITVVCESCMGSVPPGMVFRETRDGNGSTRVGFCAYWMPGNENPALRNFIQLL
HHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
EERCPPLGVRLNGV
HHHCCCCCEEECCC
>Mature Secondary Structure
MRVRDLGMLPVELKHLRYADAASQHGSFRKAADALGLKQSNLSRRIRTLEECLGYRLFER
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHH
TNGGVQPTPMGRDFLQGARRVLDDVQAIVDAADAVARGAAGQLRLGFYTSLSAGNLRSTL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHH
LDYARRFPQVRISVVEDERCRLCAGLRNGKIDIAIVTGEPTAEGGTSMALWSERILIALP
HHHHHHCCCEEEEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEECC
EAHELAAKEVLNWGDLKRERFVLSTRDPGPEIESILIAKLVTPGESLNIDHHDVNAESLK
CHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
SLVSAGHGITVVCESCMGSVPPGMVFRETRDGNGSTRVGFCAYWMPGNENPALRNFIQLL
HHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
EERCPPLGVRLNGV
HHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]