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The map label for this gene is mdtA [H]

Identifier: 154244687

GI number: 154244687

Start: 821224

End: 822387

Strand: Direct

Name: mdtA [H]

Synonym: Xaut_0736

Alternate gene names: 154244687

Gene position: 821224-822387 (Clockwise)

Preceding gene: 154244686

Following gene: 154244688

Centisome position: 15.47

GC content: 60.82

Gene sequence:

>1164_bases
ATGTCTGTCCGAAACCTGTGTCGCATAATTCTCGTCGGCGCCGGTGCAGCGATTGCCGTCGTCGGACTGCTCTATTGGCA
ATTTGCGCCGAGTCCTCCGCAAGAGCGCAGCGCGCGCTCGCAGGCGCCCGCGCCGGCACCTGTGAGCGTCGCGACGGTGA
CGAGACAGGACGTCCCGATTCATCTCTCAGGACTGGGAACGGTGCAGGCGTCATTGACCGTCGGTATCCGTTCCCAAGTC
GACGGCAAACTGCAGGAGGTGCTATTTACCGAAGGACAACGCGTCCGGAAGGGCGACGTATTGGCGAAGATCGATCCGCG
ACTGTTCCAGGCGGCGCTCGATCAAGCCATAGCCAGGAAGAGGCAGAACGCCGCATTGCTGGCTGGTGCGGAAAAAGATC
TGGCACGCTCGAAGGCGCTCGCGCAAAAGGATATCGGCACGCAACAGAATGTCGACCAGCAGCAGGCCAAGGTCGATCAG
TTGAAAGCCTCCATCGAGGCTGACATGGCTGCGATAGCCACCGCGCAAACTCAGCTTAACTACGCCACGATCGCCGCGCC
AAGCGACGGCCGCATGGGCGTCCGACTGGTTGACCCCGGCAATCTGATACGCGTGTCGGAGTCCGGACCGATTGCCACTC
TCGTGCAGATCCAACCTGCGGCGGTTCAATTCACGCTGCCGGCGCGCGTGCTGCCGGACCTACGGGAGGCTATGGCGCGC
GGGCCTGTCGAGGTTACGGCCTTCGACCAAGACAACAGGCGCGCGCTCGACACGGGTACGATTCTGCTTATCGACAATGT
CATCGATCAGGCCACCGACATGATTCGTCTCAAGGCCATGTTTGCCAATGCTGATGACCAACTGTGGCCGGGTCAATATG
TTAATGCGCGTGTGCTGGTCGCGATCAAGCGCAACGTACTGACAATCCCGTCCAGCGCAGTACAACGCGGACCGCAGGGT
CTGTTCGCCTGGATCGTGACGAGTAAGAACAATGCGGAGCCGCGTCCACTTCAGGTCGGACTGACGACGAGTGATCTGAC
GGTGGTTGCATCAGGCCTGTCCGAAGGAGAGCGCGTCGTAATCGATGGGCATTACCGGCTGCGGCGCGGCGCTTTGGTGA
CTATCGCAAAGCCGCAATCCGTCGATGCACGGAGTGGATCGTGA

Upstream 100 bases:

>100_bases
GTCCATTCCCAGGCCGTTAAAGGACTAGCTCGCCTCTGACGCCGGTCAACTCGAATAAACCGGGTTTCTTATCTGCAGGC
GCATCAGACAAAAGGTGGAT

Downstream 100 bases:

>100_bases
ATCTCTCCGACCTATCGATCAGGCGACCGGTCGCAATCACGCTGCTGATGGCGGCGCTAGCCCTTGTCGGAATGACATCA
TTCTTCCTCTTGCCCGTTGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSVRNLCRIILVGAGAAIAVVGLLYWQFAPSPPQERSARSQAPAPAPVSVATVTRQDVPIHLSGLGTVQASLTVGIRSQV
DGKLQEVLFTEGQRVRKGDVLAKIDPRLFQAALDQAIARKRQNAALLAGAEKDLARSKALAQKDIGTQQNVDQQQAKVDQ
LKASIEADMAAIATAQTQLNYATIAAPSDGRMGVRLVDPGNLIRVSESGPIATLVQIQPAAVQFTLPARVLPDLREAMAR
GPVEVTAFDQDNRRALDTGTILLIDNVIDQATDMIRLKAMFANADDQLWPGQYVNARVLVAIKRNVLTIPSSAVQRGPQG
LFAWIVTSKNNAEPRPLQVGLTTSDLTVVASGLSEGERVVIDGHYRLRRGALVTIAKPQSVDARSGS

Sequences:

>Translated_387_residues
MSVRNLCRIILVGAGAAIAVVGLLYWQFAPSPPQERSARSQAPAPAPVSVATVTRQDVPIHLSGLGTVQASLTVGIRSQV
DGKLQEVLFTEGQRVRKGDVLAKIDPRLFQAALDQAIARKRQNAALLAGAEKDLARSKALAQKDIGTQQNVDQQQAKVDQ
LKASIEADMAAIATAQTQLNYATIAAPSDGRMGVRLVDPGNLIRVSESGPIATLVQIQPAAVQFTLPARVLPDLREAMAR
GPVEVTAFDQDNRRALDTGTILLIDNVIDQATDMIRLKAMFANADDQLWPGQYVNARVLVAIKRNVLTIPSSAVQRGPQG
LFAWIVTSKNNAEPRPLQVGLTTSDLTVVASGLSEGERVVIDGHYRLRRGALVTIAKPQSVDARSGS
>Mature_386_residues
SVRNLCRIILVGAGAAIAVVGLLYWQFAPSPPQERSARSQAPAPAPVSVATVTRQDVPIHLSGLGTVQASLTVGIRSQVD
GKLQEVLFTEGQRVRKGDVLAKIDPRLFQAALDQAIARKRQNAALLAGAEKDLARSKALAQKDIGTQQNVDQQQAKVDQL
KASIEADMAAIATAQTQLNYATIAAPSDGRMGVRLVDPGNLIRVSESGPIATLVQIQPAAVQFTLPARVLPDLREAMARG
PVEVTAFDQDNRRALDTGTILLIDNVIDQATDMIRLKAMFANADDQLWPGQYVNARVLVAIKRNVLTIPSSAVQRGPQGL
FAWIVTSKNNAEPRPLQVGLTTSDLTVVASGLSEGERVVIDGHYRLRRGALVTIAKPQSVDARSGS

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=336, Percent_Identity=42.8571428571429, Blast_Score=264, Evalue=6e-72,
Organism=Escherichia coli, GI1789929, Length=361, Percent_Identity=26.5927977839335, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1786668, Length=374, Percent_Identity=29.144385026738, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1789665, Length=306, Percent_Identity=28.7581699346405, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41370; Mature: 41239

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRNLCRIILVGAGAAIAVVGLLYWQFAPSPPQERSARSQAPAPAPVSVATVTRQDVPI
CCHHHEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCE
HLSGLGTVQASLTVGIRSQVDGKLQEVLFTEGQRVRKGDVLAKIDPRLFQAALDQAIARK
EEECCCEEEEEEEEEEHHHCCHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHH
RQNAALLAGAEKDLARSKALAQKDIGTQQNVDQQQAKVDQLKASIEADMAAIATAQTQLN
HCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YATIAAPSDGRMGVRLVDPGNLIRVSESGPIATLVQIQPAAVQFTLPARVLPDLREAMAR
EEEEECCCCCCEEEEEECCCCEEEEECCCCEEEEEEECCCEEEEECCHHHHHHHHHHHHC
GPVEVTAFDQDNRRALDTGTILLIDNVIDQATDMIRLKAMFANADDQLWPGQYVNARVLV
CCEEEEEECCCCCEEECCCCEEEEEHHHHHHHHHHEEHHEECCCCCCCCCCCCCCCEEEE
AIKRNVLTIPSSAVQRGPQGLFAWIVTSKNNAEPRPLQVGLTTSDLTVVASGLSEGERVV
EEECCEEECCCHHHHCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHEECCCCCCCEEE
IDGHYRLRRGALVTIAKPQSVDARSGS
ECCCEEEECCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SVRNLCRIILVGAGAAIAVVGLLYWQFAPSPPQERSARSQAPAPAPVSVATVTRQDVPI
CHHHEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCE
HLSGLGTVQASLTVGIRSQVDGKLQEVLFTEGQRVRKGDVLAKIDPRLFQAALDQAIARK
EEECCCEEEEEEEEEEHHHCCHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHH
RQNAALLAGAEKDLARSKALAQKDIGTQQNVDQQQAKVDQLKASIEADMAAIATAQTQLN
HCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YATIAAPSDGRMGVRLVDPGNLIRVSESGPIATLVQIQPAAVQFTLPARVLPDLREAMAR
EEEEECCCCCCEEEEEECCCCEEEEECCCCEEEEEEECCCEEEEECCHHHHHHHHHHHHC
GPVEVTAFDQDNRRALDTGTILLIDNVIDQATDMIRLKAMFANADDQLWPGQYVNARVLV
CCEEEEEECCCCCEEECCCCEEEEEHHHHHHHHHHEEHHEECCCCCCCCCCCCCCCEEEE
AIKRNVLTIPSSAVQRGPQGLFAWIVTSKNNAEPRPLQVGLTTSDLTVVASGLSEGERVV
EEECCEEECCCHHHHCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHEECCCCCCCEEE
IDGHYRLRRGALVTIAKPQSVDARSGS
ECCCEEEECCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA