Click here to switch to the map view.

The map label for this gene is frc [H]

Identifier: 154244444

GI number: 154244444

Start: 540325

End: 541602

Strand: Direct

Name: frc [H]

Synonym: Xaut_0487

Alternate gene names: 154244444

Gene position: 540325-541602 (Clockwise)

Preceding gene: 154244443

Following gene: 154244445

Centisome position: 10.18

GC content: 68.62

Gene sequence:

>1278_bases
ATGGGCAAGGCACTAGAGGGGGTCCGCATCCTGGACTTCACCCACGTTCAATCCGGCCCGAGCTGCACCCAGCTGCTCGC
ATGGTTCGGTGCCGACGTGATCAAGGTGGAGCGGCCGGGCGAAGGCGACGTGACGCGCGGCCAGCTGCGCGATGTCGACG
ACGCGGACAGCCTCTATTTCACCATGCTCAACTCCAACAAGCGCTCCATCACGCTCGACACCAAGACCGCGGACGGCAAG
GCCGTGCTGGAGGACCTGGTGCGGCGCTGCGACGTGCTGGTGGAGAATTTCGCCCCCGGTGCGCTGGATCGCATGGGGCT
GACGTGGGAACGCCTGTCCGCCATCAATCCGCGCCTCATCCTGGCCTCGGTGAAGGGCTTCGGCCCCGGCCCGTTCGAGG
ACTGCAAGGTCTATGAGAACGTGGCCCAGTGCGCCGGCGGCGCGGCCTCCACCACCGGCTTCCGCGATGGGCCGCCCGTG
GTCAGCGCCGCCCAGATCGGCGACAGCGGCACCGGCCTGCATCTGGCGCTGGGCATCGTCACCGCGCTGTTCCAGCGCGA
GCACACCGGACGCGGCCAGAAGGTGCTGTGCGCCATGCAGGACGCGGTGCTGAACCTGTGCCGGGTGAAGCTGCGCGACC
AGCAGCGCCTCGGCCACGGCCCGCTAAAGGAATACAGCCAGTTCGGCGAGGGCGTCCCGTTCGGCGAGACCGTGCCCCGC
GCCGGCAACGACTCGGGCGGCGGCCAGCCCGGCCGCATCCTGCGCTGCAAGGGCTGGGAGCAGGACCCCAACGCCTACAT
CTACTTCATCACCCAGGGCCCGGTGTGGGCGAAGATCTGCGACGTCATCGGCGAGCCGGAGTGGAAGACCAAGCCGGACT
ATGCGAGCCCGGCCGCCCGCCTGCCGCATCTCAACGAGATCTTCACCCGCATCGAGGCGTGGACCATGGCCCACACCAAG
TTCGAGGCCATGGAGATCCTCAACCAGTACGACATCCCCTGCGGTCCGATCCTGTCCATGAAGGAGATCGCCGAGGACCG
CTCGCTCTACGCCACCGGCACGCTGGTGGAGGTGGAGCACCCGGTGCGCGGCACCTACCTCACAGTCGGCAACCCCATCA
AGCTCTCGGACAACCAGGTGGATGTGGAGCGCTCGCCGCTGCTCGGGGAGCACACGGACGAGGTGCTCTCCCAGGTGCTG
GGCCTTGCCCCTGACCGCATTGACGCCCTGCGCCAGTCGGGTGCGCTCGGCGCGCCGCGCCGGATGGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CCGCCTGTCAAACCCGAAGACCAAATAACAAAAACAGTAAACCGGGAACGAGACACTAGAAGCGGCGCAGCGTCGCAAGA
CCAGCCGGAGCGAGGACAAG

Downstream 100 bases:

>100_bases
GGCATCGCGCCTCCGGGCGGCACCCTGAGGGGCCGCCCCTTGCCGCCGGCCGCATGCCGGCGGGGAGCAAAAGGCAGGAA
GGAACGGAAGTCATGACTGC

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGKALEGVRILDFTHVQSGPSCTQLLAWFGADVIKVERPGEGDVTRGQLRDVDDADSLYFTMLNSNKRSITLDTKTADGK
AVLEDLVRRCDVLVENFAPGALDRMGLTWERLSAINPRLILASVKGFGPGPFEDCKVYENVAQCAGGAASTTGFRDGPPV
VSAAQIGDSGTGLHLALGIVTALFQREHTGRGQKVLCAMQDAVLNLCRVKLRDQQRLGHGPLKEYSQFGEGVPFGETVPR
AGNDSGGGQPGRILRCKGWEQDPNAYIYFITQGPVWAKICDVIGEPEWKTKPDYASPAARLPHLNEIFTRIEAWTMAHTK
FEAMEILNQYDIPCGPILSMKEIAEDRSLYATGTLVEVEHPVRGTYLTVGNPIKLSDNQVDVERSPLLGEHTDEVLSQVL
GLAPDRIDALRQSGALGAPRRMAAE

Sequences:

>Translated_425_residues
MGKALEGVRILDFTHVQSGPSCTQLLAWFGADVIKVERPGEGDVTRGQLRDVDDADSLYFTMLNSNKRSITLDTKTADGK
AVLEDLVRRCDVLVENFAPGALDRMGLTWERLSAINPRLILASVKGFGPGPFEDCKVYENVAQCAGGAASTTGFRDGPPV
VSAAQIGDSGTGLHLALGIVTALFQREHTGRGQKVLCAMQDAVLNLCRVKLRDQQRLGHGPLKEYSQFGEGVPFGETVPR
AGNDSGGGQPGRILRCKGWEQDPNAYIYFITQGPVWAKICDVIGEPEWKTKPDYASPAARLPHLNEIFTRIEAWTMAHTK
FEAMEILNQYDIPCGPILSMKEIAEDRSLYATGTLVEVEHPVRGTYLTVGNPIKLSDNQVDVERSPLLGEHTDEVLSQVL
GLAPDRIDALRQSGALGAPRRMAAE
>Mature_424_residues
GKALEGVRILDFTHVQSGPSCTQLLAWFGADVIKVERPGEGDVTRGQLRDVDDADSLYFTMLNSNKRSITLDTKTADGKA
VLEDLVRRCDVLVENFAPGALDRMGLTWERLSAINPRLILASVKGFGPGPFEDCKVYENVAQCAGGAASTTGFRDGPPVV
SAAQIGDSGTGLHLALGIVTALFQREHTGRGQKVLCAMQDAVLNLCRVKLRDQQRLGHGPLKEYSQFGEGVPFGETVPRA
GNDSGGGQPGRILRCKGWEQDPNAYIYFITQGPVWAKICDVIGEPEWKTKPDYASPAARLPHLNEIFTRIEAWTMAHTKF
EAMEILNQYDIPCGPILSMKEIAEDRSLYATGTLVEVEHPVRGTYLTVGNPIKLSDNQVDVERSPLLGEHTDEVLSQVLG
LAPDRIDALRQSGALGAPRRMAAE

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=416, Percent_Identity=29.8076923076923, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI300863124, Length=442, Percent_Identity=28.5067873303167, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI300863126, Length=152, Percent_Identity=42.7631578947368, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI42794625, Length=415, Percent_Identity=28.1927710843373, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI266456254, Length=415, Percent_Identity=28.1927710843373, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI13376042, Length=442, Percent_Identity=25.3393665158371, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI266458397, Length=215, Percent_Identity=34.8837209302326, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI266458393, Length=215, Percent_Identity=34.8837209302326, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI266458395, Length=126, Percent_Identity=39.6825396825397, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI42822893, Length=154, Percent_Identity=37.012987012987, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788717, Length=418, Percent_Identity=62.200956937799, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI87082093, Length=373, Percent_Identity=32.4396782841823, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1786222, Length=366, Percent_Identity=23.4972677595628, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32564160, Length=210, Percent_Identity=27.6190476190476, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115535051, Length=212, Percent_Identity=26.8867924528302, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24648431, Length=419, Percent_Identity=33.1742243436754, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24585488, Length=197, Percent_Identity=31.4720812182741, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 46267; Mature: 46136

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKALEGVRILDFTHVQSGPSCTQLLAWFGADVIKVERPGEGDVTRGQLRDVDDADSLYF
CCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
TMLNSNKRSITLDTKTADGKAVLEDLVRRCDVLVENFAPGALDRMGLTWERLSAINPRLI
EEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCEEE
LASVKGFGPGPFEDCKVYENVAQCAGGAASTTGFRDGPPVVSAAQIGDSGTGLHLALGIV
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHCCCCCCCHHHHHHHH
TALFQREHTGRGQKVLCAMQDAVLNLCRVKLRDQQRLGHGPLKEYSQFGEGVPFGETVPR
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
AGNDSGGGQPGRILRCKGWEQDPNAYIYFITQGPVWAKICDVIGEPEWKTKPDYASPAAR
CCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHH
LPHLNEIFTRIEAWTMAHTKFEAMEILNQYDIPCGPILSMKEIAEDRSLYATGTLVEVEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEECEEEEECC
PVRGTYLTVGNPIKLSDNQVDVERSPLLGEHTDEVLSQVLGLAPDRIDALRQSGALGAPR
CCCCEEEEECCEEEECCCEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCH
RMAAE
HHCCC
>Mature Secondary Structure 
GKALEGVRILDFTHVQSGPSCTQLLAWFGADVIKVERPGEGDVTRGQLRDVDDADSLYF
CCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
TMLNSNKRSITLDTKTADGKAVLEDLVRRCDVLVENFAPGALDRMGLTWERLSAINPRLI
EEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCEEE
LASVKGFGPGPFEDCKVYENVAQCAGGAASTTGFRDGPPVVSAAQIGDSGTGLHLALGIV
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHCCCCCCCHHHHHHHH
TALFQREHTGRGQKVLCAMQDAVLNLCRVKLRDQQRLGHGPLKEYSQFGEGVPFGETVPR
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
AGNDSGGGQPGRILRCKGWEQDPNAYIYFITQGPVWAKICDVIGEPEWKTKPDYASPAAR
CCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHH
LPHLNEIFTRIEAWTMAHTKFEAMEILNQYDIPCGPILSMKEIAEDRSLYATGTLVEVEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEECEEEEECC
PVRGTYLTVGNPIKLSDNQVDVERSPLLGEHTDEVLSQVLGLAPDRIDALRQSGALGAPR
CCCCEEEEECCEEEECCCEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCH
RMAAE
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA