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The map label for this gene is pbpG [H]

Identifier: 154244319

GI number: 154244319

Start: 374733

End: 376958

Strand: Reverse

Name: pbpG [H]

Synonym: Xaut_0362

Alternate gene names: 154244319

Gene position: 376958-374733 (Counterclockwise)

Preceding gene: 154244320

Following gene: 154244318

Centisome position: 7.1

GC content: 70.66

Gene sequence:

>2226_bases
ATGACGGCACGCGGACGAGGCGAGGCAACGAGGCGGGAACCGGTGCTGGAGCGCCCCGAGAGCCTGTTCGACATCCGTCT
CGATGCCCGCGACCGTTCCGCCCCGCCCCCAGTCGATGCACCGCGCCGGGCCGCGCGCGCCAAGACCGCCAAGCCGGCGC
CCGACCCGAAGCCCGCCGAGCCGCGCCGTGGCCGGGCCGATCCGCCCCAGAAGTCCAGAGAGAGCAGCAGGCCAGCCCGC
CGCCGGCGGCGCGGGTCGCTCGTGTTCGGGCTGATCAAATGGGGCCTCATCCTCGGCGTATGGGCGGTGCTGGCACTGGC
CGGCGTCATCGCGTGGGAAGCCTCCAAGCTGCCGCCCATGCAGACGCTGATGATCCCCAAGCGTCCGCCCACGGTGACCG
TGCAGGCCGCAGACGGCAAGACGCTGGCCACCCGTGGCGACATGGGCGGGGTCGCCGTGCCCATCGGCGAGCTGCCGCCC
TATCTGCCCAAGGCGTTCGTGGCCATCGAGGACCAGCGCTTCTTCAGCCATTTCGGCCTCGATCCGGAGGGCCTCGCCCG
CGCGCTGGTCACCAACCTCACCTCGCGGCGGCTGCGGCAGGGCGGCTCGACCCTGACCCAGCAGCTCGCCAAGAACCTGT
TCCTGACCCAGGAGCGCACGGCCTCCCGCAAGGTCCAGGAACTGGTGCTCGCCTTGTGGCTGGAGCACAAGTTCACCAAG
GCGGAGATCCTCGACCTCTATCTCAACCGGGTCTATTTCGGCGCCGGCGCCTATGGGGTGGAGGCCGCCGCCCAGCGCTA
TTTCGGCAAGTCCGCCCGGCAGGTGACGCTGGCGGAAGCGGCCATGCTGGCCGGCCTCGTCAATTCCCCCTCCCGCCTTG
CCCCCACCCGCAACCTGAAGGGCGCGCAGGCCCGCGCCGGGCTGGTGCTCGCCGCCATGCGCCAGCAGGGCCTCATCACC
CCGGAGATGGCGAGCACGGCTTTGGCCCGTCCGGCCCAGCTCTCGCGCGCCGGCATGCCGGACTCGTCGGGCTATGTGGC
CGACTGGGTCATGGACCAGCTCGACTCCTTCGTGGGCGAGGATCTGCCCGGTGATGTCACCGTGCGCACCACGGTGGATG
CCGGCCTCCAGCAGGCGGCGGAAAAGGCCCTGGACGACACGCTGGCGAAGTCCGGCGGCAAGTTTGGCGTCGGCCAGGGG
GCGCTGGTGGTGCTCGACACCGACGGGGGGGTCAAAGCCCTCATCGGCGGGCGCAATTATGCCGACAGCCAGTACAACCG
GGCAGTGACCGCGCGCCGGCAGCCCGGCTCCGCCTTCAAGCCCTTCATCTATCTCACCGCCATCGAGCACGGCCTGACAC
CTGAGACGGTGCGCGAGGACGGGCCGATCCAGCTCAAGGGCTGGCGGCCGGAAAACTCCACCCACGAATATCGCGGCCCG
GTGACGCTGACGCAGGCGCTGGCCCTGTCGCTGAACACGGTCTCGGTGCGCCTCACGCTGGAGGTCGGCCCCAAGGCGGT
GGTGGCGACGGCGAAGCGGCTGGGCATCACCTCCCCGCTGGATCCCAACCCGTCCATCGCGCTCGGCACCTCGGAAGTCT
CGGTGCTGGAGCTGGCCGGTGCCTATGTGCCGTTCGCCACCGGCGGCATCGGCGTCATCCCCCACGTCATCGACGTGGTG
AAGGGCGCCGACGGCAAAGTGCTGTACCAGCGCAACATTTCCGGTCCCGGCCGGGTCATGGACCCGGCCTATGCGGCCAT
GATGAACCACATGATGATGGAGACGCTGGCGAGCGGCACTGCCCGGCGCGCCGATCTTCCCGGCTGGGAGGCGGCGGGCA
AGACCGGCACCTCCCAGGATTATCGCGACGCCTGGTTCGTGGGCTACACCGCCCGCTACGTCACCGCCGTGTGGCTCGGC
AACGACGACAGCTCCCCCACGAAGAAGGCGTCCGGCGCCAATCTGCCGGTGGAGATCTGGAGCCGGGTGATGAAGACCGC
GCACCAGGGCGTGCCGGTGGCCGAGCTGCCGGGGGGCCTGCGCTCCTACGGCTTCGGCGGCGCCGGCTATGGCGCACCGG
GGGGCAGCCTCTTGCCGCCGGAGAGCCTGCCGGATGATCGCCCGCCCGCCGTGGTGGGCCAGATGCCGCCGCCGCCCCAG
CCGGAACAGCCCATGACCATCGACCGCTGGTTCGCCGAAACCTTCCTGGGCGCCAAGCGGCAGTAA

Upstream 100 bases:

>100_bases
GGGTGCCTTCCGCTGCGCTGCGCTTCCGCCCCATTTTGGTGCTGCAAGGGGTATGGCTCCCGCAGTGCGGCGGACGGGGG
CATAAGCGACGGGATCATTC

Downstream 100 bases:

>100_bases
TGCCAACGGCTCCGGTCTTCGACCGGTGCCGAGAGGGCGACGCTCAGCAACTCGGGTGTTCCCGAGTTGCCGATCTCAAG
ACCGGTTCCGGCAATAGCCA

Product: 1A family penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MTARGRGEATRREPVLERPESLFDIRLDARDRSAPPPVDAPRRAARAKTAKPAPDPKPAEPRRGRADPPQKSRESSRPAR
RRRRGSLVFGLIKWGLILGVWAVLALAGVIAWEASKLPPMQTLMIPKRPPTVTVQAADGKTLATRGDMGGVAVPIGELPP
YLPKAFVAIEDQRFFSHFGLDPEGLARALVTNLTSRRLRQGGSTLTQQLAKNLFLTQERTASRKVQELVLALWLEHKFTK
AEILDLYLNRVYFGAGAYGVEAAAQRYFGKSARQVTLAEAAMLAGLVNSPSRLAPTRNLKGAQARAGLVLAAMRQQGLIT
PEMASTALARPAQLSRAGMPDSSGYVADWVMDQLDSFVGEDLPGDVTVRTTVDAGLQQAAEKALDDTLAKSGGKFGVGQG
ALVVLDTDGGVKALIGGRNYADSQYNRAVTARRQPGSAFKPFIYLTAIEHGLTPETVREDGPIQLKGWRPENSTHEYRGP
VTLTQALALSLNTVSVRLTLEVGPKAVVATAKRLGITSPLDPNPSIALGTSEVSVLELAGAYVPFATGGIGVIPHVIDVV
KGADGKVLYQRNISGPGRVMDPAYAAMMNHMMMETLASGTARRADLPGWEAAGKTGTSQDYRDAWFVGYTARYVTAVWLG
NDDSSPTKKASGANLPVEIWSRVMKTAHQGVPVAELPGGLRSYGFGGAGYGAPGGSLLPPESLPDDRPPAVVGQMPPPPQ
PEQPMTIDRWFAETFLGAKRQ

Sequences:

>Translated_741_residues
MTARGRGEATRREPVLERPESLFDIRLDARDRSAPPPVDAPRRAARAKTAKPAPDPKPAEPRRGRADPPQKSRESSRPAR
RRRRGSLVFGLIKWGLILGVWAVLALAGVIAWEASKLPPMQTLMIPKRPPTVTVQAADGKTLATRGDMGGVAVPIGELPP
YLPKAFVAIEDQRFFSHFGLDPEGLARALVTNLTSRRLRQGGSTLTQQLAKNLFLTQERTASRKVQELVLALWLEHKFTK
AEILDLYLNRVYFGAGAYGVEAAAQRYFGKSARQVTLAEAAMLAGLVNSPSRLAPTRNLKGAQARAGLVLAAMRQQGLIT
PEMASTALARPAQLSRAGMPDSSGYVADWVMDQLDSFVGEDLPGDVTVRTTVDAGLQQAAEKALDDTLAKSGGKFGVGQG
ALVVLDTDGGVKALIGGRNYADSQYNRAVTARRQPGSAFKPFIYLTAIEHGLTPETVREDGPIQLKGWRPENSTHEYRGP
VTLTQALALSLNTVSVRLTLEVGPKAVVATAKRLGITSPLDPNPSIALGTSEVSVLELAGAYVPFATGGIGVIPHVIDVV
KGADGKVLYQRNISGPGRVMDPAYAAMMNHMMMETLASGTARRADLPGWEAAGKTGTSQDYRDAWFVGYTARYVTAVWLG
NDDSSPTKKASGANLPVEIWSRVMKTAHQGVPVAELPGGLRSYGFGGAGYGAPGGSLLPPESLPDDRPPAVVGQMPPPPQ
PEQPMTIDRWFAETFLGAKRQ
>Mature_740_residues
TARGRGEATRREPVLERPESLFDIRLDARDRSAPPPVDAPRRAARAKTAKPAPDPKPAEPRRGRADPPQKSRESSRPARR
RRRGSLVFGLIKWGLILGVWAVLALAGVIAWEASKLPPMQTLMIPKRPPTVTVQAADGKTLATRGDMGGVAVPIGELPPY
LPKAFVAIEDQRFFSHFGLDPEGLARALVTNLTSRRLRQGGSTLTQQLAKNLFLTQERTASRKVQELVLALWLEHKFTKA
EILDLYLNRVYFGAGAYGVEAAAQRYFGKSARQVTLAEAAMLAGLVNSPSRLAPTRNLKGAQARAGLVLAAMRQQGLITP
EMASTALARPAQLSRAGMPDSSGYVADWVMDQLDSFVGEDLPGDVTVRTTVDAGLQQAAEKALDDTLAKSGGKFGVGQGA
LVVLDTDGGVKALIGGRNYADSQYNRAVTARRQPGSAFKPFIYLTAIEHGLTPETVREDGPIQLKGWRPENSTHEYRGPV
TLTQALALSLNTVSVRLTLEVGPKAVVATAKRLGITSPLDPNPSIALGTSEVSVLELAGAYVPFATGGIGVIPHVIDVVK
GADGKVLYQRNISGPGRVMDPAYAAMMNHMMMETLASGTARRADLPGWEAAGKTGTSQDYRDAWFVGYTARYVTAVWLGN
DDSSPTKKASGANLPVEIWSRVMKTAHQGVPVAELPGGLRSYGFGGAGYGAPGGSLLPPESLPDDRPPAVVGQMPPPPQP
EQPMTIDRWFAETFLGAKRQ

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=539, Percent_Identity=35.9925788497217, Blast_Score=241, Evalue=2e-64,
Organism=Escherichia coli, GI1788867, Length=570, Percent_Identity=32.9824561403509, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI87082258, Length=313, Percent_Identity=37.0607028753994, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI1789601, Length=165, Percent_Identity=40, Blast_Score=113, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 79378; Mature: 79247

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARGRGEATRREPVLERPESLFDIRLDARDRSAPPPVDAPRRAARAKTAKPAPDPKPAE
CCCCCCCCCHHCCCHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
PRRGRADPPQKSRESSRPARRRRRGSLVFGLIKWGLILGVWAVLALAGVIAWEASKLPPM
CCCCCCCCCHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QTLMIPKRPPTVTVQAADGKTLATRGDMGGVAVPIGELPPYLPKAFVAIEDQRFFSHFGL
CEEECCCCCCEEEEEECCCCEEEECCCCCCEEEECCCCCCCCCCEEEEEEHHHHHHHCCC
DPEGLARALVTNLTSRRLRQGGSTLTQQLAKNLFLTQERTASRKVQELVLALWLEHKFTK
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHH
AEILDLYLNRVYFGAGAYGVEAAAQRYFGKSARQVTLAEAAMLAGLVNSPSRLAPTRNLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCC
GAQARAGLVLAAMRQQGLITPEMASTALARPAQLSRAGMPDSSGYVADWVMDQLDSFVGE
CCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
DLPGDVTVRTTVDAGLQQAAEKALDDTLAKSGGKFGVGQGALVVLDTDGGVKALIGGRNY
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCC
ADSQYNRAVTARRQPGSAFKPFIYLTAIEHGLTPETVREDGPIQLKGWRPENSTHEYRGP
CCHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCC
VTLTQALALSLNTVSVRLTLEVGPKAVVATAKRLGITSPLDPNPSIALGTSEVSVLELAG
HHHHHHHHHEEEEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHC
AYVPFATGGIGVIPHVIDVVKGADGKVLYQRNISGPGRVMDPAYAAMMNHMMMETLASGT
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
ARRADLPGWEAAGKTGTSQDYRDAWFVGYTARYVTAVWLGNDDSSPTKKASGANLPVEIW
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEHEEEEEEEEECCCCCCCCCCCCCCCCCHHHH
SRVMKTAHQGVPVAELPGGLRSYGFGGAGYGAPGGSLLPPESLPDDRPPAVVGQMPPPPQ
HHHHHHHHCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
PEQPMTIDRWFAETFLGAKRQ
CCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TARGRGEATRREPVLERPESLFDIRLDARDRSAPPPVDAPRRAARAKTAKPAPDPKPAE
CCCCCCCCHHCCCHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
PRRGRADPPQKSRESSRPARRRRRGSLVFGLIKWGLILGVWAVLALAGVIAWEASKLPPM
CCCCCCCCCHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QTLMIPKRPPTVTVQAADGKTLATRGDMGGVAVPIGELPPYLPKAFVAIEDQRFFSHFGL
CEEECCCCCCEEEEEECCCCEEEECCCCCCEEEECCCCCCCCCCEEEEEEHHHHHHHCCC
DPEGLARALVTNLTSRRLRQGGSTLTQQLAKNLFLTQERTASRKVQELVLALWLEHKFTK
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHH
AEILDLYLNRVYFGAGAYGVEAAAQRYFGKSARQVTLAEAAMLAGLVNSPSRLAPTRNLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCC
GAQARAGLVLAAMRQQGLITPEMASTALARPAQLSRAGMPDSSGYVADWVMDQLDSFVGE
CCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
DLPGDVTVRTTVDAGLQQAAEKALDDTLAKSGGKFGVGQGALVVLDTDGGVKALIGGRNY
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCC
ADSQYNRAVTARRQPGSAFKPFIYLTAIEHGLTPETVREDGPIQLKGWRPENSTHEYRGP
CCHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCC
VTLTQALALSLNTVSVRLTLEVGPKAVVATAKRLGITSPLDPNPSIALGTSEVSVLELAG
HHHHHHHHHEEEEEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHC
AYVPFATGGIGVIPHVIDVVKGADGKVLYQRNISGPGRVMDPAYAAMMNHMMMETLASGT
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
ARRADLPGWEAAGKTGTSQDYRDAWFVGYTARYVTAVWLGNDDSSPTKKASGANLPVEIW
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEHEEEEEEEEECCCCCCCCCCCCCCCCCHHHH
SRVMKTAHQGVPVAELPGGLRSYGFGGAGYGAPGGSLLPPESLPDDRPPAVVGQMPPPPQ
HHHHHHHHCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
PEQPMTIDRWFAETFLGAKRQ
CCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]