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The map label for this gene is aspC [H]

Identifier: 154244257

GI number: 154244257

Start: 307533

End: 308816

Strand: Direct

Name: aspC [H]

Synonym: Xaut_0300

Alternate gene names: 154244257

Gene position: 307533-308816 (Clockwise)

Preceding gene: 154244255

Following gene: 154244258

Centisome position: 5.79

GC content: 69.94

Gene sequence:

>1284_bases
ATGAATTCGCGTGCGTTCCCTGCGCCTGAAGATCCGTCCGCCACCCCTGAGTCTTCCCACCTGCCGCTGACGCCCGTCGG
CGCGGGGGAAGACCCCTATCTGGAGCGGGTGCGCGACCCTATCCGCACCCTGCCCGAGAGCGGCATCGTCGAGGTGATGA
ATTACGGCCGCGACCGGCCCGGCATGATCCCGCTGTGGGCCGGGGAGGGGGATGTGGCCACACCCCCCTTCATCTGCGAG
GCCGCCGCCACCGCGCTGCACGCGGGCGAGACCTTCTACACCTGGCAGCGCGGCCTGCCGGAGCTGCGTGGCGCCATCGC
CCGATACATGGCGCGCACCTATGGCATTCCGGAAAATCCGGACCGCTATTTCGTCACCGGCTCGGGCATGCAGGCGATCC
ATATCGCGCTGGCCATGACGGCGGGGGCGGGGGACGAGGTGATCATTCCCTCGCCGTCCTGGCCCAATGCCGCCGCGGCG
GCGCAGAAGGCCGGGGCGCGGCCGGTGTACGTGCCCTTCGCCTATGGCAAGGACGGCTTCAGCCTCGACCATGAGCGGCT
GGCGCAGGCCATCACGCCGCGCACCCGCGCCATCTTCCTCAACACCCCGGCCAATCCCACCGGATTCGTGGCCACACACG
ACGACCTCAGGGCGGTGCTGGCGCTGGCCCGCCGGCACGGCCTGTGGATCATCGCCGACGAGATCTACGGCCGCTTCTAT
TATGGGGATGAGCCCCGCGCGCCCTCCTTCCACGACGTGATGGACGAGGGCGACCACATCCTGTTCGTGCAGACCTTCTC
CAAGAACTGGGCCATGACCGGCTGGCGTGTGGGCTGGATCGAGGCCGACCCGCGGCTGGGGCAGGTGATCGAGAACCTGA
TCCAGTATTCCACCTCCGGCGTCGCCGCCTTCATGCAGCGCGGCGCGGTGGCGGCGCTCGATCAGGGCGAGGATTTCGTC
GCCCAGCAGATCGCCCGCGCCCGCAAGGGCCGCGACCGCGTCGCTGACGCGCTCATCGCCACCGGAAAGGTGGATCTGGT
GAAGCCGCCGGGGGCCTTCTACCTGTTCTTCGGCATCGCGGGCCGGAGCGACGTGCGCAGCCTCGGCCTGACCCTGGTGG
ACGAGGCCAATGTGGGCCTTGCCCCCGGTACCGCGTTCGGTCCCGGAGGGGAGGGCTTCATGCGCCTGTGCTTTGCCCGG
GGCGATGCCCAGCTCGCCGAGGCGAGCCGCCGCCTCGTGGCCTGGCTCACGGGAGACGGGCAGACGGGAGCAGGCGCGGC
GTGA

Upstream 100 bases:

>100_bases
GCGCTGCTGATCGGTTCTCCACTGCAATTGATGGGTGCTCCGCCGCCGAAGCCTCTATAAGTCGCGGCCTGTCCCGATCG
CCCCGTTCCGCGAGCCTGCC

Downstream 100 bases:

>100_bases
GGCCTCTTGCCTCCCACCTGCGGTCGGCCGTCGCGGCGGCAATAACTTTGGGGGCGGGCGCGCTTGGTGGCGGCGTGTTC
GCCGCCCTCGGCCTGCCCGC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MNSRAFPAPEDPSATPESSHLPLTPVGAGEDPYLERVRDPIRTLPESGIVEVMNYGRDRPGMIPLWAGEGDVATPPFICE
AAATALHAGETFYTWQRGLPELRGAIARYMARTYGIPENPDRYFVTGSGMQAIHIALAMTAGAGDEVIIPSPSWPNAAAA
AQKAGARPVYVPFAYGKDGFSLDHERLAQAITPRTRAIFLNTPANPTGFVATHDDLRAVLALARRHGLWIIADEIYGRFY
YGDEPRAPSFHDVMDEGDHILFVQTFSKNWAMTGWRVGWIEADPRLGQVIENLIQYSTSGVAAFMQRGAVAALDQGEDFV
AQQIARARKGRDRVADALIATGKVDLVKPPGAFYLFFGIAGRSDVRSLGLTLVDEANVGLAPGTAFGPGGEGFMRLCFAR
GDAQLAEASRRLVAWLTGDGQTGAGAA

Sequences:

>Translated_427_residues
MNSRAFPAPEDPSATPESSHLPLTPVGAGEDPYLERVRDPIRTLPESGIVEVMNYGRDRPGMIPLWAGEGDVATPPFICE
AAATALHAGETFYTWQRGLPELRGAIARYMARTYGIPENPDRYFVTGSGMQAIHIALAMTAGAGDEVIIPSPSWPNAAAA
AQKAGARPVYVPFAYGKDGFSLDHERLAQAITPRTRAIFLNTPANPTGFVATHDDLRAVLALARRHGLWIIADEIYGRFY
YGDEPRAPSFHDVMDEGDHILFVQTFSKNWAMTGWRVGWIEADPRLGQVIENLIQYSTSGVAAFMQRGAVAALDQGEDFV
AQQIARARKGRDRVADALIATGKVDLVKPPGAFYLFFGIAGRSDVRSLGLTLVDEANVGLAPGTAFGPGGEGFMRLCFAR
GDAQLAEASRRLVAWLTGDGQTGAGAA
>Mature_427_residues
MNSRAFPAPEDPSATPESSHLPLTPVGAGEDPYLERVRDPIRTLPESGIVEVMNYGRDRPGMIPLWAGEGDVATPPFICE
AAATALHAGETFYTWQRGLPELRGAIARYMARTYGIPENPDRYFVTGSGMQAIHIALAMTAGAGDEVIIPSPSWPNAAAA
AQKAGARPVYVPFAYGKDGFSLDHERLAQAITPRTRAIFLNTPANPTGFVATHDDLRAVLALARRHGLWIIADEIYGRFY
YGDEPRAPSFHDVMDEGDHILFVQTFSKNWAMTGWRVGWIEADPRLGQVIENLIQYSTSGVAAFMQRGAVAALDQGEDFV
AQQIARARKGRDRVADALIATGKVDLVKPPGAFYLFFGIAGRSDVRSLGLTLVDEANVGLAPGTAFGPGGEGFMRLCFAR
GDAQLAEASRRLVAWLTGDGQTGAGAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=417, Percent_Identity=26.8585131894484, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI95147551, Length=394, Percent_Identity=26.6497461928934, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI169881279, Length=394, Percent_Identity=26.6497461928934, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=22.4489795918367, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI56713254, Length=392, Percent_Identity=22.4489795918367, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI169881281, Length=339, Percent_Identity=25.6637168141593, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4885351, Length=208, Percent_Identity=31.25, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=28.9617486338798, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786816, Length=381, Percent_Identity=27.0341207349081, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788627, Length=331, Percent_Identity=29.0030211480363, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787710, Length=297, Percent_Identity=26.9360269360269, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790797, Length=372, Percent_Identity=24.1935483870968, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787909, Length=356, Percent_Identity=25.561797752809, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=362, Percent_Identity=25.6906077348066, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=22.3057644110276, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=353, Percent_Identity=21.5297450424929, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=353, Percent_Identity=21.5297450424929, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=233, Percent_Identity=29.1845493562232, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=24.4845360824742, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=24.4845360824742, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=24.4845360824742, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=24.4845360824742, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356535, Length=347, Percent_Identity=23.342939481268, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI18859735, Length=372, Percent_Identity=24.1935483870968, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 45944; Mature: 45944

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRAFPAPEDPSATPESSHLPLTPVGAGEDPYLERVRDPIRTLPESGIVEVMNYGRDRP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
GMIPLWAGEGDVATPPFICEAAATALHAGETFYTWQRGLPELRGAIARYMARTYGIPENP
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEHHHCCCHHHHHHHHHHHHHHCCCCCCC
DRYFVTGSGMQAIHIALAMTAGAGDEVIIPSPSWPNAAAAAQKAGARPVYVPFAYGKDGF
CEEEEECCCCCEEEEEEEEECCCCCEEEECCCCCCCHHHHHHHCCCCEEEEEEEECCCCC
SLDHERLAQAITPRTRAIFLNTPANPTGFVATHDDLRAVLALARRHGLWIIADEIYGRFY
CCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHCCEEEEEHHHCCEEE
YGDEPRAPSFHDVMDEGDHILFVQTFSKNWAMTGWRVGWIEADPRLGQVIENLIQYSTSG
ECCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCH
VAAFMQRGAVAALDQGEDFVAQQIARARKGRDRVADALIATGKVDLVKPPGAFYLFFGIA
HHHHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCEEEEEEEC
GRSDVRSLGLTLVDEANVGLAPGTAFGPGGEGFMRLCFARGDAQLAEASRRLVAWLTGDG
CCHHHHHHCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCEEEEEEECCC
QTGAGAA
CCCCCCC
>Mature Secondary Structure
MNSRAFPAPEDPSATPESSHLPLTPVGAGEDPYLERVRDPIRTLPESGIVEVMNYGRDRP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
GMIPLWAGEGDVATPPFICEAAATALHAGETFYTWQRGLPELRGAIARYMARTYGIPENP
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEHHHCCCHHHHHHHHHHHHHHCCCCCCC
DRYFVTGSGMQAIHIALAMTAGAGDEVIIPSPSWPNAAAAAQKAGARPVYVPFAYGKDGF
CEEEEECCCCCEEEEEEEEECCCCCEEEECCCCCCCHHHHHHHCCCCEEEEEEEECCCCC
SLDHERLAQAITPRTRAIFLNTPANPTGFVATHDDLRAVLALARRHGLWIIADEIYGRFY
CCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHCCEEEEEHHHCCEEE
YGDEPRAPSFHDVMDEGDHILFVQTFSKNWAMTGWRVGWIEADPRLGQVIENLIQYSTSG
ECCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCH
VAAFMQRGAVAALDQGEDFVAQQIARARKGRDRVADALIATGKVDLVKPPGAFYLFFGIA
HHHHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCEEEEEEEC
GRSDVRSLGLTLVDEANVGLAPGTAFGPGGEGFMRLCFARGDAQLAEASRRLVAWLTGDG
CCHHHHHHCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCEEEEEEECCC
QTGAGAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]