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The map label for this gene is yjjN [H]

Identifier: 154244136

GI number: 154244136

Start: 174277

End: 175287

Strand: Direct

Name: yjjN [H]

Synonym: Xaut_0178

Alternate gene names: 154244136

Gene position: 174277-175287 (Clockwise)

Preceding gene: 154244135

Following gene: 154244137

Centisome position: 3.28

GC content: 67.85

Gene sequence:

>1011_bases
ATGAAGGCATTACTCTGCGAAGAACCGGGTCGCCTGTCGGTCATCAGCCGGCCCGTGCCGGTGCCTGCCGCCGGCGAGGT
GCTCGTGCGCATCCGCCGCGTGGGCGTGTGCGGCACCGATTTCCACATCTTCCAGGGCAAGCACCCCTTCCTCGAATATC
CCCGCGTCATGGGCCACGAATTGTCGGGCACCGTCGAGGCGGCGCCCGAGGGCAGCCGCCTGAAGACCGGCGAGAACGTC
TACATCGTGCCCTACCTCTCCTGCGGAAAGTGCGTGGCCTGCCGCAAGGGCGTGACCAATGCCTGCCAGAACATCGCCGT
GCTGGGCGTCCACAAGGACGGCGGCATGGCGGAATTCCTCTGCGTGCCCGAGGGCAATGTGGTGCCCACCGGCACCGCCT
CCCTCGACGACGCGGCCATGATCGAGTTCCTCGCCATCGGCGCCCATGGCGTTAAGCGCGGCCAGGTCACGGCTGAGGAC
AAGGTGCTGGTGGTGGGTTCCGGCCCCATCGGCATGTCCGCCATCATCTTCGCCAAGGCGCGGGGCGCGCAGGTCTCGGT
GATGGACATGCGGGAGGATCGCCTCGCCTTCACCAGGGACATGCTGGGCGCCGACCATCTGGTGACGGCGGATGCCGGCG
CCGAGGAAGCCGCCAAGCGCATCACCCAGGGCGATTTCTACGACGTGGTGATCGACGCCACCGGCAATGCGGGGGCCATG
CAGCGGGGCTTCGGCTTCATCGCCCATGGCGGGCGCTATGTGCTGGTCAGCGTGGTGCGGCAGGACATCACCTTCTCCGA
TCCCGAGTTCCACAAGCGCGAGACCACGCTCTACGCCAGCCGCAACGCCCAGCCCGATGATTTCGCGGAAGTGGTGCGCC
AGATGGAGGCCGGCCGCGTGCCGACGCGCGCGCTCAACACCCATCGCGGCGCCCTCGGCGATGCGCCCGGGCTGTTCCAG
GACTGGCTGAAGCCCGAGGCCGGCGTCATCAAGGCGATTCTGGAGGTCTGA

Upstream 100 bases:

>100_bases
AGAAATGCTGAAGTGAGGCTTCTGGCGGCCCGGTTGATCCGGGCCGCTTCCTGCGGCTGGTCTTGAATGTCGGTCGCATA
TTTCAGGAAAGAATTGGACG

Downstream 100 bases:

>100_bases
CGCATCATGGCCGACCCGCGCACTCTGCGTCTCAACGCGGCGGACAATGTCCTCATCGCCATCGATACCGTCCCGCAGGG
TGCGGCGCTGCCCGGAGGCC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKALLCEEPGRLSVISRPVPVPAAGEVLVRIRRVGVCGTDFHIFQGKHPFLEYPRVMGHELSGTVEAAPEGSRLKTGENV
YIVPYLSCGKCVACRKGVTNACQNIAVLGVHKDGGMAEFLCVPEGNVVPTGTASLDDAAMIEFLAIGAHGVKRGQVTAED
KVLVVGSGPIGMSAIIFAKARGAQVSVMDMREDRLAFTRDMLGADHLVTADAGAEEAAKRITQGDFYDVVIDATGNAGAM
QRGFGFIAHGGRYVLVSVVRQDITFSDPEFHKRETTLYASRNAQPDDFAEVVRQMEAGRVPTRALNTHRGALGDAPGLFQ
DWLKPEAGVIKAILEV

Sequences:

>Translated_336_residues
MKALLCEEPGRLSVISRPVPVPAAGEVLVRIRRVGVCGTDFHIFQGKHPFLEYPRVMGHELSGTVEAAPEGSRLKTGENV
YIVPYLSCGKCVACRKGVTNACQNIAVLGVHKDGGMAEFLCVPEGNVVPTGTASLDDAAMIEFLAIGAHGVKRGQVTAED
KVLVVGSGPIGMSAIIFAKARGAQVSVMDMREDRLAFTRDMLGADHLVTADAGAEEAAKRITQGDFYDVVIDATGNAGAM
QRGFGFIAHGGRYVLVSVVRQDITFSDPEFHKRETTLYASRNAQPDDFAEVVRQMEAGRVPTRALNTHRGALGDAPGLFQ
DWLKPEAGVIKAILEV
>Mature_336_residues
MKALLCEEPGRLSVISRPVPVPAAGEVLVRIRRVGVCGTDFHIFQGKHPFLEYPRVMGHELSGTVEAAPEGSRLKTGENV
YIVPYLSCGKCVACRKGVTNACQNIAVLGVHKDGGMAEFLCVPEGNVVPTGTASLDDAAMIEFLAIGAHGVKRGQVTAED
KVLVVGSGPIGMSAIIFAKARGAQVSVMDMREDRLAFTRDMLGADHLVTADAGAEEAAKRITQGDFYDVVIDATGNAGAM
QRGFGFIAHGGRYVLVSVVRQDITFSDPEFHKRETTLYASRNAQPDDFAEVVRQMEAGRVPTRALNTHRGALGDAPGLFQ
DWLKPEAGVIKAILEV

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=342, Percent_Identity=30.9941520467836, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4501929, Length=261, Percent_Identity=29.5019157088123, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI71743840, Length=261, Percent_Identity=29.1187739463602, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI262073058, Length=261, Percent_Identity=29.1187739463602, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI71565154, Length=270, Percent_Identity=27.037037037037, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4501939, Length=236, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI34577061, Length=260, Percent_Identity=28.0769230769231, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI156523966, Length=236, Percent_Identity=26.271186440678, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI226510992, Length=313, Percent_Identity=42.8115015974441, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1787863, Length=335, Percent_Identity=34.0298507462687, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1788073, Length=353, Percent_Identity=27.7620396600567, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87082125, Length=275, Percent_Identity=33.0909090909091, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788407, Length=326, Percent_Identity=26.9938650306748, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790045, Length=272, Percent_Identity=30.8823529411765, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786825, Length=267, Percent_Identity=31.8352059925094, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790718, Length=225, Percent_Identity=29.7777777777778, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788075, Length=328, Percent_Identity=22.8658536585366, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=253, Percent_Identity=33.9920948616601, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17562878, Length=197, Percent_Identity=34.010152284264, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25146526, Length=266, Percent_Identity=27.4436090225564, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=348, Percent_Identity=26.1494252873563, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322619, Length=348, Percent_Identity=26.1494252873563, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323099, Length=347, Percent_Identity=24.7838616714697, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319257, Length=355, Percent_Identity=27.3239436619718, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319258, Length=320, Percent_Identity=25.3125, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320033, Length=352, Percent_Identity=25.2840909090909, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=210, Percent_Identity=29.5238095238095, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=211, Percent_Identity=27.9620853080569, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=194, Percent_Identity=29.8969072164948, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17137530, Length=337, Percent_Identity=29.080118694362, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17737897, Length=341, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45551930, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550770, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221457811, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737895, Length=337, Percent_Identity=23.7388724035608, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35930; Mature: 35930

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLCEEPGRLSVISRPVPVPAAGEVLVRIRRVGVCGTDFHIFQGKHPFLEYPRVMGHE
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHCHHHHCCC
LSGTVEAAPEGSRLKTGENVYIVPYLSCGKCVACRKGVTNACQNIAVLGVHKDGGMAEFL
CCCEEECCCCCCCEECCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCEEEE
CVPEGNVVPTGTASLDDAAMIEFLAIGAHGVKRGQVTAEDKVLVVGSGPIGMSAIIFAKA
ECCCCCEECCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCCCEEEEEEEC
RGAQVSVMDMREDRLAFTRDMLGADHLVTADAGAEEAAKRITQGDFYDVVIDATGNAGAM
CCCEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCH
QRGFGFIAHGGRYVLVSVVRQDITFSDPEFHKRETTLYASRNAQPDDFAEVVRQMEAGRV
HHCCEEEECCCEEEEEEHHHHCCCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PTRALNTHRGALGDAPGLFQDWLKPEAGVIKAILEV
CHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MKALLCEEPGRLSVISRPVPVPAAGEVLVRIRRVGVCGTDFHIFQGKHPFLEYPRVMGHE
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHCHHHHCCC
LSGTVEAAPEGSRLKTGENVYIVPYLSCGKCVACRKGVTNACQNIAVLGVHKDGGMAEFL
CCCEEECCCCCCCEECCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCEEEE
CVPEGNVVPTGTASLDDAAMIEFLAIGAHGVKRGQVTAEDKVLVVGSGPIGMSAIIFAKA
ECCCCCEECCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCCCEEEEEEEC
RGAQVSVMDMREDRLAFTRDMLGADHLVTADAGAEEAAKRITQGDFYDVVIDATGNAGAM
CCCEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCH
QRGFGFIAHGGRYVLVSVVRQDITFSDPEFHKRETTLYASRNAQPDDFAEVVRQMEAGRV
HHCCEEEECCCEEEEEEHHHHCCCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PTRALNTHRGALGDAPGLFQDWLKPEAGVIKAILEV
CHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]