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The map label for this gene is sseA [H]

Identifier: 154244058

GI number: 154244058

Start: 107055

End: 107915

Strand: Reverse

Name: sseA [H]

Synonym: Xaut_0100

Alternate gene names: 154244058

Gene position: 107915-107055 (Counterclockwise)

Preceding gene: 154244059

Following gene: 154244057

Centisome position: 2.03

GC content: 65.51

Gene sequence:

>861_bases
ATGTCCACCGTTCTTCCCGGACCGTTGGTAAGCACCGAATGGCTGGCCGAGCATCTCGAAGCGCCGGACGTGAAGATCCT
GGACTGCACCTGGCTGCATGAAAGCAGCAATATGGACGGGAAGACCCAGTATCGCGGGCGTCATCTTCCCGGCTCGGTGC
ATTTCGACATCGATCATGTGGCCGACAAGACCAATCCCCTCCCCCACATGCTTCCGCCCGCCGCGGAGTTCGCCAAGAAG
GTCGGCCTTCTTGGCATCGCCGACGGCGACAAGATCGTGGTCTATGATCGCCTGTGCGGCGGTGCGGCCGCGGCCCGGGT
GTGGTGGATGTTCCGCAGCTTCGGCTACGACGACGTGGCCGTGCTGGACGGCGGCTACGGCAAATGGGTGAAGGAGAAGA
AGCCCTCCGACATGTCGCCCGTGCGGCCGGAGCCCAAGACCTTCACAGCGACCTTCAATCCGGCACTCGTGCGCAACCTC
GGCGAGATGGTGGCCAATGTCGCCAGCAAGGCCGACCAGGTCGTCGACGCGCGCGGGCCTGCCAAGTTTGCCGGCACCCA
GGACGACGTGTTCCCGGTGAAGAAAAAGGGCCACATCCCCGGCTCGGTCAACCTGCCCTGGGGCGACCTGATCGTCGAAG
AAAGCGGCGAGCTGATCCAGCCCGACGCGCTGGCGGCTCGTTTCTCCGCCGCCGGCATCGACATCGCCAAGCCGGTTGTG
GCGACCTGCGCTTCCGGCACCATTTCGGCTGTGGTGCTGCTCGCGCTGTTCATCCTCGGCAACAAGACGGCGGCGCTCTA
CGACGGCTCGTGGGCCGAATGGGGCCTTGCCGAAGACACTCCGGCGGCCGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
CCAAAGCGGGCCGCCATTTCAAGATTGTCTGCCGGGCTACACGCCCGGCGGGCCTGACAAGCACCCGATGTCCGAACCTC
GACAGGGAGAGACCCGCGTC

Downstream 100 bases:

>100_bases
CGGGAGCAACCGATGGCCGATCTTCTGCCCCTCATCAGCGACGGCGAGGAGTTCACCCTTCTCGCCTCGGACGACAACAC
CCATTTCGTGCTCCGCTTCA

Product: rhodanese domain-containing protein

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSTVLPGPLVSTEWLAEHLEAPDVKILDCTWLHESSNMDGKTQYRGRHLPGSVHFDIDHVADKTNPLPHMLPPAAEFAKK
VGLLGIADGDKIVVYDRLCGGAAAARVWWMFRSFGYDDVAVLDGGYGKWVKEKKPSDMSPVRPEPKTFTATFNPALVRNL
GEMVANVASKADQVVDARGPAKFAGTQDDVFPVKKKGHIPGSVNLPWGDLIVEESGELIQPDALAARFSAAGIDIAKPVV
ATCASGTISAVVLLALFILGNKTAALYDGSWAEWGLAEDTPAAAAA

Sequences:

>Translated_286_residues
MSTVLPGPLVSTEWLAEHLEAPDVKILDCTWLHESSNMDGKTQYRGRHLPGSVHFDIDHVADKTNPLPHMLPPAAEFAKK
VGLLGIADGDKIVVYDRLCGGAAAARVWWMFRSFGYDDVAVLDGGYGKWVKEKKPSDMSPVRPEPKTFTATFNPALVRNL
GEMVANVASKADQVVDARGPAKFAGTQDDVFPVKKKGHIPGSVNLPWGDLIVEESGELIQPDALAARFSAAGIDIAKPVV
ATCASGTISAVVLLALFILGNKTAALYDGSWAEWGLAEDTPAAAAA
>Mature_285_residues
STVLPGPLVSTEWLAEHLEAPDVKILDCTWLHESSNMDGKTQYRGRHLPGSVHFDIDHVADKTNPLPHMLPPAAEFAKKV
GLLGIADGDKIVVYDRLCGGAAAARVWWMFRSFGYDDVAVLDGGYGKWVKEKKPSDMSPVRPEPKTFTATFNPALVRNLG
EMVANVASKADQVVDARGPAKFAGTQDDVFPVKKKGHIPGSVNLPWGDLIVEESGELIQPDALAARFSAAGIDIAKPVVA
TCASGTISAVVLLALFILGNKTAALYDGSWAEWGLAEDTPAAAAA

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI17402865, Length=277, Percent_Identity=40.072202166065, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI194473668, Length=271, Percent_Identity=38.0073800738007, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI61835204, Length=271, Percent_Identity=38.0073800738007, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI194473681, Length=271, Percent_Identity=38.0073800738007, Blast_Score=211, Evalue=8e-55,
Organism=Escherichia coli, GI87082121, Length=276, Percent_Identity=37.6811594202899, Blast_Score=194, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17561888, Length=290, Percent_Identity=28.2758620689655, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71997283, Length=299, Percent_Identity=26.7558528428094, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115534702, Length=238, Percent_Identity=26.4705882352941, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543836, Length=300, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17543838, Length=300, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559150, Length=254, Percent_Identity=24.0157480314961, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324825, Length=268, Percent_Identity=31.7164179104478, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 30499; Mature: 30368

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00683 RHODANESE_2 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLPGPLVSTEWLAEHLEAPDVKILDCTWLHESSNMDGKTQYRGRHLPGSVHFDIDHV
CCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHCCCCCCCCEEEEEHHHH
ADKTNPLPHMLPPAAEFAKKVGLLGIADGDKIVVYDRLCGGAAAARVWWMFRSFGYDDVA
HCCCCCCCCCCCCHHHHHHHHCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEE
VLDGGYGKWVKEKKPSDMSPVRPEPKTFTATFNPALVRNLGEMVANVASKADQVVDARGP
EEECCCCCCHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
AKFAGTQDDVFPVKKKGHIPGSVNLPWGDLIVEESGELIQPDALAARFSAAGIDIAKPVV
CCCCCCCCCCCCCHHCCCCCCCCCCCHHHEEEECCCCEECCHHHHHHHHHCCCCHHHHHH
ATCASGTISAVVLLALFILGNKTAALYDGSWAEWGLAEDTPAAAAA
HHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
STVLPGPLVSTEWLAEHLEAPDVKILDCTWLHESSNMDGKTQYRGRHLPGSVHFDIDHV
CCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHCCCCCCCCEEEEEHHHH
ADKTNPLPHMLPPAAEFAKKVGLLGIADGDKIVVYDRLCGGAAAARVWWMFRSFGYDDVA
HCCCCCCCCCCCCHHHHHHHHCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEE
VLDGGYGKWVKEKKPSDMSPVRPEPKTFTATFNPALVRNLGEMVANVASKADQVVDARGP
EEECCCCCCHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
AKFAGTQDDVFPVKKKGHIPGSVNLPWGDLIVEESGELIQPDALAARFSAAGIDIAKPVV
CCCCCCCCCCCCCHHCCCCCCCCCCCHHHEEEECCCCEECCHHHHHHHHHCCCCHHHHHH
ATCASGTISAVVLLALFILGNKTAALYDGSWAEWGLAEDTPAAAAA
HHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]