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The map label for this gene is mog [H]

Identifier: 154244007

GI number: 154244007

Start: 52721

End: 53443

Strand: Direct

Name: mog [H]

Synonym: Xaut_0049

Alternate gene names: 154244007

Gene position: 52721-53443 (Clockwise)

Preceding gene: 154244005

Following gene: 154244013

Centisome position: 0.99

GC content: 69.99

Gene sequence:

>723_bases
GTGACGCTGAGATGGACACGGGGAAATGGACACGGGCTTGCATTTCGGCCCCGGTCGCGCCAGCACAGGCGGACCGCCTT
GGAGCCGGGCCCGATCGGGTTGAACCCGCCTGATCGGCGCATCCGTCTCCCGCCCTCGAGATCGGGGACGCGCAGCCAGC
GCGTGCTCTGGACCAACCGGATCGCTCCCATGTCGCCAGCCCGCATCGGCATCGTCACCATTTCGGACCGCGCCAGCTCC
GGCGGCTATGCCGACCTCTCGGGGCCGGCCATCGAGGCATGGCTGCGGCAGGCCATCACCAGCCCCTGGAGCGTCGACTA
TCGGGTCATTCCGGACGGTTTCGAGAGTGTGCGCGATACCCTGATCGACATGTGCGACCATGCCGGCCTCGACCTCATCT
GCACCACCGGCGGCACCGGCCCGGCCCCGCGCGACCTGACCCCTGAGGCCATGGCGGCGGTGATCGAGAAGCCGCTGCCC
GGCTTCGGCGAGCAGATGCGCCGCATCAGCCTGAACGAGGTGCCCACCGCCATCCTGTCGCGGCAGGAGGCGGGGGTGCG
CGGCAAGACCCTGATCGTGAACCTGCCGGGCAAGCCGGCCTCCATCGCGGTGTGCCTCGGGGCGGTGTTCCCGGCCATTC
CCTATTGCCTCGACCTCATCGGCGCGGGGCGCATCGAGACCGACCCGCAGGTGTGCGTCGCCTTCCGCCCCAAGGGAGCG
TGA

Upstream 100 bases:

>100_bases
GCAGGAACCCGAAAAAAACGACACGTTTCACCTATATTCACATGAATACGGTTTCACGCGAAATTCAACCTCTATCGCTG
CGGTATGGCGGCGCGCCCGG

Downstream 100 bases:

>100_bases
GGCCTTGGAGCGTGAGGCCTTGGGAGCGCGATTAAAGCACCACCACGCCGCGGTGCTTGGCCTCGCCTTCCGGCTCCACG
TGGATGGTGATGATGGCGTC

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTLRWTRGNGHGLAFRPRSRQHRRTALEPGPIGLNPPDRRIRLPPSRSGTRSQRVLWTNRIAPMSPARIGIVTISDRASS
GGYADLSGPAIEAWLRQAITSPWSVDYRVIPDGFESVRDTLIDMCDHAGLDLICTTGGTGPAPRDLTPEAMAAVIEKPLP
GFGEQMRRISLNEVPTAILSRQEAGVRGKTLIVNLPGKPASIAVCLGAVFPAIPYCLDLIGAGRIETDPQVCVAFRPKGA

Sequences:

>Translated_240_residues
MTLRWTRGNGHGLAFRPRSRQHRRTALEPGPIGLNPPDRRIRLPPSRSGTRSQRVLWTNRIAPMSPARIGIVTISDRASS
GGYADLSGPAIEAWLRQAITSPWSVDYRVIPDGFESVRDTLIDMCDHAGLDLICTTGGTGPAPRDLTPEAMAAVIEKPLP
GFGEQMRRISLNEVPTAILSRQEAGVRGKTLIVNLPGKPASIAVCLGAVFPAIPYCLDLIGAGRIETDPQVCVAFRPKGA
>Mature_239_residues
TLRWTRGNGHGLAFRPRSRQHRRTALEPGPIGLNPPDRRIRLPPSRSGTRSQRVLWTNRIAPMSPARIGIVTISDRASSG
GYADLSGPAIEAWLRQAITSPWSVDYRVIPDGFESVRDTLIDMCDHAGLDLICTTGGTGPAPRDLTPEAMAAVIEKPLPG
FGEQMRRISLNEVPTAILSRQEAGVRGKTLIVNLPGKPASIAVCLGAVFPAIPYCLDLIGAGRIETDPQVCVAFRPKGA

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=154, Percent_Identity=42.2077922077922, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI66932975, Length=154, Percent_Identity=42.2077922077922, Blast_Score=125, Evalue=3e-29,
Organism=Escherichia coli, GI1786190, Length=189, Percent_Identity=48.6772486772487, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787000, Length=133, Percent_Identity=33.0827067669173, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=156, Percent_Identity=35.2564102564103, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI17136978, Length=158, Percent_Identity=32.9113924050633, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638841, Length=158, Percent_Identity=32.9113924050633, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 25887; Mature: 25756

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRWTRGNGHGLAFRPRSRQHRRTALEPGPIGLNPPDRRIRLPPSRSGTRSQRVLWTNR
CEEEEECCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEECC
IAPMSPARIGIVTISDRASSGGYADLSGPAIEAWLRQAITSPWSVDYRVIPDGFESVRDT
CCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
LIDMCDHAGLDLICTTGGTGPAPRDLTPEAMAAVIEKPLPGFGEQMRRISLNEVPTAILS
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
RQEAGVRGKTLIVNLPGKPASIAVCLGAVFPAIPYCLDLIGAGRIETDPQVCVAFRPKGA
HHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
TLRWTRGNGHGLAFRPRSRQHRRTALEPGPIGLNPPDRRIRLPPSRSGTRSQRVLWTNR
EEEEECCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEECC
IAPMSPARIGIVTISDRASSGGYADLSGPAIEAWLRQAITSPWSVDYRVIPDGFESVRDT
CCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
LIDMCDHAGLDLICTTGGTGPAPRDLTPEAMAAVIEKPLPGFGEQMRRISLNEVPTAILS
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
RQEAGVRGKTLIVNLPGKPASIAVCLGAVFPAIPYCLDLIGAGRIETDPQVCVAFRPKGA
HHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]