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The map label for this gene is can [H]

Identifier: 153950851

GI number: 153950851

Start: 3765550

End: 3766212

Strand: Direct

Name: can [H]

Synonym: YpsIP31758_3350

Alternate gene names: 153950851

Gene position: 3765550-3766212 (Clockwise)

Preceding gene: 153947423

Following gene: 153949088

Centisome position: 79.72

GC content: 45.1

Gene sequence:

>663_bases
ATGAAAGAAATAGAAAAGCTCATCGCGAACAATCGAACTTGGTCAAACACCATTTGTAAAGATGATCCCGGTTTTTTTGA
GCACTTGGCACAATCTCAGAAACCGCGCTTCTTATGGATTGGTTGTTCAGACAGTCGCGTTCCCGCAGAGCAGTTAACTG
GATTGAAATCAGGCGAGTTATTTGTTCACCGTAACGTTGCCAATCTGGTTATCCATACCGATCTTAACTGCCTATCGGTC
GTCCAATACGCTATTGATGTTCTTCAGGTAGAACACATTATTATCTGTGGCCACCTTGGCTGTGGTGGTGTTGAAGCGGC
CATCAAAGGCGAAGAGATGGGGCTTATCGATAACTGGTTACTGCACATTCGGGACCTTTGGTATAAACACAGTTCATTGT
TGGGTGAACTGCCACAAGAAGAACGCAGTAATGTGTTGTGTCAGATAAACGTAGTAGAGCAAGTGTATAACCTTGGTCAT
TCAACCATTGTGCGTTCGGCCTGGAAGCGCGGGCAAAAAGCCATGATCCACGGCTGGGTATATGGTATTGAAAATGGCCT
GCTGCGTGATCTAGAAGTCTCAGCCACCAGCCTTGGTAGCCTGGAAATGGTGTATCGCAAAGCAATGGCTGAGTTATTAC
AAAACAATAAAGAAGACCATTAA

Upstream 100 bases:

>100_bases
ATATCGCGTTATTACCGAAACTACTGTTCCGATTTCAAAATCGGAATCCTTGCCGTATATTATTCTATCGCAACCCGAAC
ACTACAGGCTATTTACATTG

Downstream 100 bases:

>100_bases
GTCGCTCTGGGAGGGTACGTTAAAACGCGCCCTCTCCCACAAAATCCTTCCGCTAAATTAAGCGTCCCAGCGCGCAAGAA
CCAGAGCGTACATGCAGTAC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSV
VQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGH
STIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH

Sequences:

>Translated_220_residues
MKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSV
VQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGH
STIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH
>Mature_220_residues
MKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSV
VQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGH
STIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=73.1132075471698, Blast_Score=340, Evalue=5e-95,
Organism=Escherichia coli, GI1786534, Length=174, Percent_Identity=35.0574712643678, Blast_Score=94, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324292, Length=199, Percent_Identity=31.1557788944724, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24871; Mature: 24871

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGEL
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANLVIHTDLNCLSVVQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWL
EEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHEECCCCCCHHHHHH
LHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGHSTIVRSAWKRGQKAMIHGWV
HHHHHHHHHHHHHHHCCCHHHHCCEEEEEEHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
YGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGEL
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANLVIHTDLNCLSVVQYAIDVLQVEHIIICGHLGCGGVEAAIKGEEMGLIDNWL
EEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHEECCCCCCHHHHHH
LHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGHSTIVRSAWKRGQKAMIHGWV
HHHHHHHHHHHHHHHCCCHHHHCCEEEEEEHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
YGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]