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The map label for this gene is argS [H]

Identifier: 153950466

GI number: 153950466

Start: 2349486

End: 2351216

Strand: Direct

Name: argS [H]

Synonym: YpsIP31758_2043

Alternate gene names: 153950466

Gene position: 2349486-2351216 (Clockwise)

Preceding gene: 153947263

Following gene: 153949215

Centisome position: 49.74

GC content: 49.97

Gene sequence:

>1731_bases
GTGAATATTCAGGCTCTTCTCTCAGATAAAGTCAGCCAGGCGCTGATTGCAGCAGGTGCTCCCGCAGATTGCGAAGCTCA
AGTTCGCCAATCTGCCAAAGCTCAATTTGGCGATTATCAAGCTAACGGTGTGATGGCCGTTGCCAAAAAACTTGGCATGC
AACCCCGACAACTGGCAGAAAGAGTCGTTGAACTGCTCGACCTTACAGGTATCGCCAGTAAGATTGAAATTGCAGGCCCC
GGTTTTATCAATATTTTTCTGGATCGTCAGTGGGTGGCCGAGAAAGTCGAATATGCTCTGACTGCGCCTAAATTGGGCGT
CGCGCCTGTCGAACCGCAAACTATCGTAGTCGATTATTCAGCACCTAACGTGGCTAAACAGATGCACGTTGGTCACCTGC
GATCCACCATTATTGGTGATGCTGCAGTACGGACATTGGCGTTTTTGGGCCATAACGTTATCCGTGCCAACCACGTCGGT
GACTGGGGTACCCAGTTTGGCATGTTGATCGCCTACCTGGAGAAAATGCAGAACGAAAATGCCAGTGATATGGGGCTATC
GGATCTGGAGCTTTTCTATCAACAAGCGAAGAAAACCTACGACGAAGACGAAGAGTTTGCTCTGCGTGCCCGTGCCTATG
TCGTAAAACTGCAAAGTGGGGACGAATACTGCCGTCAAATGTGGCGTAAATTGGTGGATATCACCATGGCGCAAAACCAG
GTTGCCTATGACCGCCTGAATGTCACCTTGACCAAAGACGACGTAATGGGTGAAAGCCTGTACAACGCGATGCTGCCAGA
GATTGTCGCGGATTTGAAAGCCAAAGGGTTGGCCGTCGAGAGCGAAGGTGCGACCGTTGTTTATCTGGATGAATATAAGA
ATAAAGACGGTGAGCCAATGGGCGTCATCATCCAGAAAAAAGATGGCGGCTACCTCTACACCACCACCGATATTGCCTGC
GCCAAATACCGTTACGAAACGCTGGGCGCAGACCGGATACTCTATTACATCGATAGCCGCCAGCATCAGCATTTGATGCA
AGCCTGGGCCATCGTGCGTAAAGCCGGTTATGTGCCAGAATCCGTGCCACTGGAACACCACATGTTCGGCATGATGCTGG
GCAAAGATGGCAAACCGTTTAAAACCCGCTCTGGTGGTACCGTCAAATTATCCGATTTGCTGGACGAGGCGGTTGAACGT
GCTGGTAAGTTGATTGCCGAGAAAAACCCGGATATGCCTGCCGATGAATTGAAGCAAGTGATCAATGCGGTGGGGATTGG
CGCGGTGAAATATGCCGATTTGTCCAAGAGTCGAACCACAGACTATATTTTCGATTGGGATAATATGCTGGCGTTGGATG
GCAATACCGCACCTTATATGCAATATGCATATACTCGCGTGGTTTCAGTATTTAGACGTGCGGGTGTTGATGAAAACAGC
CTGACGTTGCCATTAGTGATTACAGAAGATCGCGAAGCCGCCTTGGCGACCCGCCTGTTGCAGTTTGAAGAGATCATCAC
CACGGTGGCACGCGAAGGCACACCGCATGTCATGTGTTCTTATCTTTATGATCTAGCAGGCTTGTTCTCCAGCTTCTACG
AGCATTGCCAGATCCTGAATGCAGAGAGCGAAGAGATCCGCCAAAGCCGCCTAAAACTGGCGATGCTAACGGCTAAAACG
CTGAAGCAAGGTCTGGATACCTTAGGTATTCAAACAGTAGAACGGATGTAA

Upstream 100 bases:

>100_bases
GTAACTGACACAGAAATGAGTCACTGGCACAGAAATGTGACTGATCCAGAATTTTTTGTGCATAATTAATCTGTCTTTCG
TATGTAATTAAGGTAACCCG

Downstream 100 bases:

>100_bases
ATCGTCAAAAAAAGGCCCCTCGGGCTGAGAGACCCCCAGAAACATCATTTATTTATGGGGAGTCTTCAGCCCAAAGGGCC
TTTATATTTCTCGAAAAACA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGP
GFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRILYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVER
AGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDENS
LTLPLVITEDREAALATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKT
LKQGLDTLGIQTVERM

Sequences:

>Translated_576_residues
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGP
GFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRILYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVER
AGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDENS
LTLPLVITEDREAALATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKT
LKQGLDTLGIQTVERM
>Mature_576_residues
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGP
GFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRILYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVER
AGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDENS
LTLPLVITEDREAALATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKT
LKQGLDTLGIQTVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=572, Percent_Identity=37.7622377622378, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI197100773, Length=539, Percent_Identity=29.8701298701299, Blast_Score=210, Evalue=3e-54,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=83.3622183708839, Blast_Score=1002, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=597, Percent_Identity=37.5209380234506, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71985068, Length=565, Percent_Identity=37.6991150442478, Blast_Score=354, Evalue=6e-98,
Organism=Caenorhabditis elegans, GI17532153, Length=384, Percent_Identity=28.3854166666667, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=32.3529411764706, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6321883, Length=538, Percent_Identity=27.5092936802974, Blast_Score=206, Evalue=6e-54,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=38.8007054673721, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI28571570, Length=487, Percent_Identity=29.5687885010267, Blast_Score=170, Evalue=3e-42,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64109; Mature: 64109

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
RVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYS
HHHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
APNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
ASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
CCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCH
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPM
HEEEHEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWAIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQV
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
INAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDENS
HHHHCCCCEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTLPLVITEDREAALATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILN
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
AESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
RVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYS
HHHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
APNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
ASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
CCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCH
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPM
HEEEHEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWAIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQV
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
INAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDENS
HHHHCCCCEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTLPLVITEDREAALATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILN
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
AESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA