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The map label for this gene is fepD [H]

Identifier: 153950457

GI number: 153950457

Start: 2754453

End: 2755493

Strand: Direct

Name: fepD [H]

Synonym: YpsIP31758_2442

Alternate gene names: 153950457

Gene position: 2754453-2755493 (Clockwise)

Preceding gene: 153947265

Following gene: 153946879

Centisome position: 58.32

GC content: 54.27

Gene sequence:

>1041_bases
ATGATAGATAACACGGTTCAACAATTACGAAAATACCGCATCTTAGGATGGATAGGGTTATTGCTGCTCACATTAATGTG
TGTGTTAGTCAGCCTGACTCTCGGGGCGAAGACCTTGCCAATCAGCGCAATCTGGCACTATATAGAGATGTACTACATCA
ATATGCCCGCCGCTCATATCAGCTATAACGATCTGGTCATTGATGCCCGGATCCCCCGTACACTGATTGGCCTCTTGGCT
GGAGCTGCACTGGCCCTCTCCGGTGCAGTGACTCAGGGGCTATTGCGCAATCCACTTGGTGACCCCGGACTATTGGGCGT
CAATGCCGGTGCATCAGCGATTATCGTCAGTTTTGCGTTCTTCCCCGCACTGGCAGCAATACCGCATTTTTGGCCTGCCC
TACTCGGTGCAGCACTAGCCACCCTGTTGTTTTATCTGTTGGGGGGCGGGCAACGGAATACACACTCGGTGCGTTTGGTG
CTTACCGGCGCGGCCATCAATGCCTGCCTGTTTGCCTATGTACAGGGGGTGGTGTTACTCAACCCTGCGGTGTTGGAAAA
TTACCGCTTCTGGATCATGGGTTCTCTGGCGGCGACATCAGTATCAGCCATGCTGGCCGTGCTCCCCTATTTTGTCATCG
GTTTGGTGATCATCTTCGCCATCGCCCCTTCGCTGAACGTGATGGTATTTGGCGAAAACGTTGCTACCACCATGGGGGCC
AATACCGTTCGGATCCGTATGTCGGCATTAGTAGGCGCAACATTGCTGACCGCTACCGCGACGGCAGTAGCGGGTCCGGT
CGCTTTTATTGGTCTGGCAGCCCCTCATTTGGGGCGAGCCATGATTGGCTCAGACTTTCGTTGGCTACTGCCTTATTGCT
TACTGCTCGGCCCAATCCTCTTGCTGAGTGCCGATGTGGTCGCCCGCATTATCATCGCCCCCGGCGAAGTGATGGTTGGC
GTGATCACCGCTGCCGTGGGAGGGCCATTGCTTTACGCGGTGGTCAACAGTAAAAAAGGTATCGTCTATGCATCCCGTTG
A

Upstream 100 bases:

>100_bases
CCTATGGCACACCGCTGAGCGTTCAGTGGGGGTTGCAACGCTTTATGCCATTGCTCGCAGAAAAAGCGCGCCACTTGGCT
GATACCAAAGAGACACTGCC

Downstream 100 bases:

>100_bases
TTCAGTCAGAATGCTGACGCTGGGATCTTGGGTCTTTTTAGCGCCAGCCCGCCGAACCGGGGTTTACCTGCTGCTGATAT
GGCCCATTTTATTGCTATGC

Product: ferric enterobactin ABC transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIDNTVQQLRKYRILGWIGLLLLTLMCVLVSLTLGAKTLPISAIWHYIEMYYINMPAAHISYNDLVIDARIPRTLIGLLA
GAALALSGAVTQGLLRNPLGDPGLLGVNAGASAIIVSFAFFPALAAIPHFWPALLGAALATLLFYLLGGGQRNTHSVRLV
LTGAAINACLFAYVQGVVLLNPAVLENYRFWIMGSLAATSVSAMLAVLPYFVIGLVIIFAIAPSLNVMVFGENVATTMGA
NTVRIRMSALVGATLLTATATAVAGPVAFIGLAAPHLGRAMIGSDFRWLLPYCLLLGPILLLSADVVARIIIAPGEVMVG
VITAAVGGPLLYAVVNSKKGIVYASR

Sequences:

>Translated_346_residues
MIDNTVQQLRKYRILGWIGLLLLTLMCVLVSLTLGAKTLPISAIWHYIEMYYINMPAAHISYNDLVIDARIPRTLIGLLA
GAALALSGAVTQGLLRNPLGDPGLLGVNAGASAIIVSFAFFPALAAIPHFWPALLGAALATLLFYLLGGGQRNTHSVRLV
LTGAAINACLFAYVQGVVLLNPAVLENYRFWIMGSLAATSVSAMLAVLPYFVIGLVIIFAIAPSLNVMVFGENVATTMGA
NTVRIRMSALVGATLLTATATAVAGPVAFIGLAAPHLGRAMIGSDFRWLLPYCLLLGPILLLSADVVARIIIAPGEVMVG
VITAAVGGPLLYAVVNSKKGIVYASR
>Mature_346_residues
MIDNTVQQLRKYRILGWIGLLLLTLMCVLVSLTLGAKTLPISAIWHYIEMYYINMPAAHISYNDLVIDARIPRTLIGLLA
GAALALSGAVTQGLLRNPLGDPGLLGVNAGASAIIVSFAFFPALAAIPHFWPALLGAALATLLFYLLGGGQRNTHSVRLV
LTGAAINACLFAYVQGVVLLNPAVLENYRFWIMGSLAATSVSAMLAVLPYFVIGLVIIFAIAPSLNVMVFGENVATTMGA
NTVRIRMSALVGATLLTATATAVAGPVAFIGLAAPHLGRAMIGSDFRWLLPYCLLLGPILLLSADVVARIIIAPGEVMVG
VITAAVGGPLLYAVVNSKKGIVYASR

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=42.8115015974441, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1790740, Length=304, Percent_Identity=34.5394736842105, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1790741, Length=277, Percent_Identity=35.0180505415162, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786804, Length=325, Percent_Identity=36.3076923076923, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788004, Length=272, Percent_Identity=36.7647058823529, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=30.2158273381295, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36347; Mature: 36347

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDNTVQQLRKYRILGWIGLLLLTLMCVLVSLTLGAKTLPISAIWHYIEMYYINMPAAHI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCHHHC
SYNDLVIDARIPRTLIGLLAGAALALSGAVTQGLLRNPLGDPGLLGVNAGASAIIVSFAF
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
FPALAAIPHFWPALLGAALATLLFYLLGGGQRNTHSVRLVLTGAAINACLFAYVQGVVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHC
NPAVLENYRFWIMGSLAATSVSAMLAVLPYFVIGLVIIFAIAPSLNVMVFGENVATTMGA
CHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCC
NTVRIRMSALVGATLLTATATAVAGPVAFIGLAAPHLGRAMIGSDFRWLLPYCLLLGPIL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHCCCHHHHHHHHHHHHHHH
LLSADVVARIIIAPGEVMVGVITAAVGGPLLYAVVNSKKGIVYASR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEECC
>Mature Secondary Structure
MIDNTVQQLRKYRILGWIGLLLLTLMCVLVSLTLGAKTLPISAIWHYIEMYYINMPAAHI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCHHHC
SYNDLVIDARIPRTLIGLLAGAALALSGAVTQGLLRNPLGDPGLLGVNAGASAIIVSFAF
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
FPALAAIPHFWPALLGAALATLLFYLLGGGQRNTHSVRLVLTGAAINACLFAYVQGVVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHC
NPAVLENYRFWIMGSLAATSVSAMLAVLPYFVIGLVIIFAIAPSLNVMVFGENVATTMGA
CHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCC
NTVRIRMSALVGATLLTATATAVAGPVAFIGLAAPHLGRAMIGSDFRWLLPYCLLLGPIL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHCCCHHHHHHHHHHHHHHH
LLSADVVARIIIAPGEVMVGVITAAVGGPLLYAVVNSKKGIVYASR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]