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The map label for this gene is mtnA [H]

Identifier: 153950389

GI number: 153950389

Start: 3583925

End: 3584965

Strand: Direct

Name: mtnA [H]

Synonym: YpsIP31758_3179

Alternate gene names: 153950389

Gene position: 3583925-3584965 (Clockwise)

Preceding gene: 153946828

Following gene: 153947866

Centisome position: 75.88

GC content: 55.62

Gene sequence:

>1041_bases
ATGCAGACGCTTAACACCCTCGACTTACAGACCACCAGCTTAAAAATTGTCAATGGTCAGCTTTGGATCCTTGACCAGCA
AGCACTGCCGCAGCGTCAAGAGTGGCTACTAGCCGATACCGTCGCCTCGTTGATTGAACATATTCAGGCGCTGCGGGTTC
GTGGTGCGCCACTTATTGGCTTGTCAGCCAGCCTGCTCTTGGCGCTACTGGCTGAACGTGGTTTATCGCAGGCTTTACTT
GAGCAAGCATTGATTGCCTTGCGTGAGTCACGCCCGACTGCCGTTAACCTCATGAATAATCTGGCACGGATGCAGCAAGC
GTTATTACAGCCCAATTGGGTTACGGCGATGGCCGCTGAAGCGCTACGATTAGTCGATGAAGACCGTGAGTTGTGTGAGC
GTATTGCCCAGCATGGGGCGGCACTAGTTAAACCCGGTAGCAACCTATTGACCCATTGCAATACTGGCGGGCTGGCCACT
GCCGGGATCGGCACCGCGATTGGCGTCTTACTGCGCGCCCATCAGCAGGGCAACCTCCGACAGGTTTGGGTTGATGAAAC
CCGGCCCTTATTACAAGGTGGGCGTTTAACCGCCTGGGAGTTAGGTGAATTGGGGATTCCCTATCAATTGATTTGCGATT
CGATGGCCGCCAGCCTGATGGCTCAGGGCCAAGTGGATGCTATCTGGGTCGGCGCTGATCGCATTGCTGCCAACGGTGAT
GTGGCGAACAAAATTGGCACCTACAGCCTGGCGGTATTGGCGCATTATCACCGAATTCCGTTCTATGTTGCCGCACCGCA
CACCACCCACGATCCAGATTGCCCTGATGGAGCAGCGATCCCGATTGAACAACGTGCTGCCAGTGAGGTGACCGGTGTCT
CTGGCGGATTTGGTCATTGCCAGTGGGCACCAGAAGACGCGGCGGTGTACAACCCAGCCTTTGATGTCACCCCTGCGGCA
TTGATCAGTGGTTGGGTGTTAGATAGCGGAGTGATCACACCTGAACAGGTCGCGGCAGGCTTTTTCCAGCCTCACCGCTA
G

Upstream 100 bases:

>100_bases
TGTATTTAGGCGTAAAAACATATGGACGTCTATACATCCGTAAAACATGTTGGCAGAATAAGAAACCAGATGCAATAACG
CAACATGGATTTAACTGACT

Downstream 100 bases:

>100_bases
CAATCAATACCCGATACTTTATATTTCTTAATATTTCTTAGTTTAGGCGAGGCGAGGATAGCCGTCGGCAATATTATCGC
CGGTAGAACGTGCTATCCAG

Product: eIF-2B alpha/beta/delta family protein

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALL
EQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLAT
AGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGD
VANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPEDAAVYNPAFDVTPAA
LISGWVLDSGVITPEQVAAGFFQPHR

Sequences:

>Translated_346_residues
MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALL
EQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLAT
AGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGD
VANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPEDAAVYNPAFDVTPAA
LISGWVLDSGVITPEQVAAGFFQPHR
>Mature_346_residues
MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALL
EQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLAT
AGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGD
VANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPEDAAVYNPAFDVTPAA
LISGWVLDSGVITPEQVAAGFFQPHR

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=354, Percent_Identity=39.5480225988701, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI23943880, Length=333, Percent_Identity=37.2372372372372, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17557462, Length=341, Percent_Identity=39.5894428152493, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17557123, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325375, Length=396, Percent_Identity=33.5858585858586, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322878, Length=207, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21357667, Length=355, Percent_Identity=39.1549295774648, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24651647, Length=355, Percent_Identity=39.1549295774648, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 37115; Mature: 37115

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIG
CCCCCCCCEEEEEEEEECCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
LSASLLLALLAERGLSQALLEQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLATAGIGTAIGVLLRAHQQGNLR
HHHHHHHHHHHHHHHHHCCCEEECCCCHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
QVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGD
EEECCCCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCC
VANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHC
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
QWAPEDAAVYNPAFDVTPAALISGWVLDSGVITPEQVAAGFFQPHR
CCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIG
CCCCCCCCEEEEEEEEECCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
LSASLLLALLAERGLSQALLEQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLATAGIGTAIGVLLRAHQQGNLR
HHHHHHHHHHHHHHHHHCCCEEECCCCHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
QVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGD
EEECCCCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCC
VANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHC
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
QWAPEDAAVYNPAFDVTPAALISGWVLDSGVITPEQVAAGFFQPHR
CCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA