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The map label for this gene is mtlR [H]

Identifier: 153950376

GI number: 153950376

Start: 4657317

End: 4657871

Strand: Reverse

Name: mtlR [H]

Synonym: YpsIP31758_4126

Alternate gene names: 153950376

Gene position: 4657871-4657317 (Counterclockwise)

Preceding gene: 153947800

Following gene: 153950725

Centisome position: 98.61

GC content: 48.47

Gene sequence:

>555_bases
ATGATTGAAAAAAAACAAGCATTTGAGAATCGGGTTCTTGAACATTTGAACGCTGGGAAGACCGTGCGCAGCTTCTTGAT
GGCGGCAGTCGATTTATTGGCTGAAGCACTGAATATACTCGTGGTGCAGATTTTTCGTAAAGATGACTATGCGGTGAAGT
ATGCCGTGGAGCCGTTATTGGTCGGTGACGGGCCATTGAGTGAACTCTCTGTGCGGTTGAAGCTGGTTTATGCCCTTGGG
GTGATCACCCGGCATGAATATGAAGATGCTGAGCTATTAATGGCGCTACGTGAAGAGCTAAACCACGATGGCACTGAGTA
TCGCTTTACCGATGACGAAATCCTCGGGCCATTTGGTGAATTGCATTGTGTCGATGAATTGCCGCCAGTACCCACTTTTT
TACGCCCTGATGAAGCCGATGCTTCGCTGATTGCTATGCAACGCCAGCGTTATCAGCAAATGGTCCGCTCCACCATGGTG
TTGTCGATCACTGAACTGCTCTCTCGCATCAGCGTCAAACAGGTCTCTAAGCTCTCGCCATTAAGTCAAGGTTAA

Upstream 100 bases:

>100_bases
CGGCAGAGGAGGAATACCGTGTTAAATTTATGCGGTGTTTATTTTGCCGTGGCGTCATAATCAGGCGGACAGGACTTCAC
CAACCTCCCAGTGACTAGCA

Downstream 100 bases:

>100_bases
TCAAGAAATTACGTTTAGCCACTCTTCTACCTGCCGTCATACTGCTATCCCTTTAATCGCCGCTATACTGAGGCATTGAT
GCGGGTTGGGCTGGCCACCT

Product: mannitol repressor protein

Products: NA

Alternate protein names: Mannitol repressor protein [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIEKKQAFENRVLEHLNAGKTVRSFLMAAVDLLAEALNILVVQIFRKDDYAVKYAVEPLLVGDGPLSELSVRLKLVYALG
VITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCVDELPPVPTFLRPDEADASLIAMQRQRYQQMVRSTMV
LSITELLSRISVKQVSKLSPLSQG

Sequences:

>Translated_184_residues
MIEKKQAFENRVLEHLNAGKTVRSFLMAAVDLLAEALNILVVQIFRKDDYAVKYAVEPLLVGDGPLSELSVRLKLVYALG
VITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCVDELPPVPTFLRPDEADASLIAMQRQRYQQMVRSTMV
LSITELLSRISVKQVSKLSPLSQG
>Mature_184_residues
MIEKKQAFENRVLEHLNAGKTVRSFLMAAVDLLAEALNILVVQIFRKDDYAVKYAVEPLLVGDGPLSELSVRLKLVYALG
VITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCVDELPPVPTFLRPDEADASLIAMQRQRYQQMVRSTMV
LSITELLSRISVKQVSKLSPLSQG

Specific function: Acts as a repressor of the mtlAD operon [H]

COG id: COG3722

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yggD [H]

Homologues:

Organism=Escherichia coli, GI1790029, Length=173, Percent_Identity=77.4566473988439, Blast_Score=274, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007761 [H]

Pfam domain/function: PF05068 MtlR [H]

EC number: NA

Molecular weight: Translated: 20814; Mature: 20814

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKKQAFENRVLEHLNAGKTVRSFLMAAVDLLAEALNILVVQIFRKDDYAVKYAVEPLL
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEE
VGDGPLSELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGE
ECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCHH
LHCVDELPPVPTFLRPDEADASLIAMQRQRYQQMVRSTMVLSITELLSRISVKQVSKLSP
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSQG
CCCC
>Mature Secondary Structure
MIEKKQAFENRVLEHLNAGKTVRSFLMAAVDLLAEALNILVVQIFRKDDYAVKYAVEPLL
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEE
VGDGPLSELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGE
ECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCHH
LHCVDELPPVPTFLRPDEADASLIAMQRQRYQQMVRSTMVLSITELLSRISVKQVSKLSP
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSQG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]