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The map label for this gene is cat2 [H]

Identifier: 153950039

GI number: 153950039

Start: 2480797

End: 2482119

Strand: Direct

Name: cat2 [H]

Synonym: YpsIP31758_2158

Alternate gene names: 153950039

Gene position: 2480797-2482119 (Clockwise)

Preceding gene: 153949436

Following gene: 153950552

Centisome position: 52.52

GC content: 50.11

Gene sequence:

>1323_bases
ATGGATATACGTGCATTGTATGACGAGAAACTCACCACGCCTGAGGAGGCCGTTTCCTCTATTGCATCCGGCAGTCATCT
CTCTATGGGGATGTTTGCGGCTGAACCACCCGCGCTGCTGAAGGCGCTGGCAGATAGGGCGACAAGGGGGGATATTGGCG
ATCTACGCGTTTACTATTTTGAAACGGCCAAAATTGCCGGTGATACTATTCTGCGCTATGAGCTAAATAACCGCATCAAG
CCCTATAGCATGTTCGTCACTGCCGTGGAGCGGGCGCTCATTCGCCGAGGTATAGAGGATGGTGGGCGTAAAGTTGTCAA
TTATGTCCCATCCAATTTTCATCAAGCACCACGTCTTCTGGCCGAAGAAATTGGTATTGATACGTTCATGCACACCGTTT
CTCCGATGGATTGCCATGGCTACTTTAGCCTCGGTGTTGGAAATGACTATTCATCCCGAATTGCACGTTCAGCCAGACGA
TTCATCGTTGAGGTGAATCAGTATATGCCGCGCGTTCAGGGGGAAGCGGCGGCGATTCACATCTCTGAAGTTGATGCCAT
TGTCGAAAATCATGTCCCTTTGATTGAGATGCCAGTACGTTCAGCAATACCCGAATATACATCTATTAGCCACATCATTG
CTGACCTCGTACCTGATGGTGCCTGCTTACAAATGGGGGTGGGCGCGCTACCAAACCTCGTTTGTGGAGTGCTAAAAGAT
CGCAATGACCTAGGGATCCATACTGAAGTGTTGAACCCCGGACTGGTCGATTTAATCCGAAGGGGGGTAGTGACGAACCA
GCGAAAAACACTGGACAGGGGCAGGTCTGTTTTCACTTTTGCCATGGGGCAACAAGAAATGTACGAATACCTTAACGATC
ACCCAGCGATTTTCAGCCGGCCGGTCGATTATGTTAACGATCCCCACATCATTGCGCAAAATGACAACGTGGTATCCATT
AATTCGACCCTGCAAATTGACCTGACGGGTGCCTGTAATTCTGAACATATGCTTGGACACCAATACAGCGCTTCGGGGGG
GCAGTTGGACTTTGTCAGGGGGGCATACGCCTCTAAAGGTGGGCGCTCCATCATCGCCACGCCTTCAACTGCGGCGAAAG
GTACTGTTTCACGTATTATTCCCCGCATTGACGGACCGGTAACCACACCCCGTATCGATACCCACTATATCGTTACCGAG
TTTGGTGCTGTTAACCTCAAAGGACTTTCTTCAACTGAACGGGCGCTGAGAATCATTGAGCTGGCACATCCTGATTTCCG
GGATGAGCTAACGCAGGCTGCCAAAAAAATGCATCTAATCTGA

Upstream 100 bases:

>100_bases
ATAGAGGTGATGAGCTTCGAACGCACGATGCTGGTTTATCGCCGCGGTCACTCACCAGAAGAAATGGCAGGATACTGAGA
AAAACAGCGAGGGTTATATC

Downstream 100 bases:

>100_bases
GATAACCACCCTGTCAACACTCTGCCAAACAGTATTTTTCGCTCTCCGGCATGGGGAGCGCTATACGGTGTTTCCCCCTG
ACGGTCATGCAGGCGGGTGA

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNQYMPRVQGEAAAIHISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI

Sequences:

>Translated_440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNQYMPRVQGEAAAIHISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI
>Mature_440_residues
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYFETAKIAGDTILRYELNNRIK
PYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLLAEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARR
FIVEVNQYMPRVQGEAAAIHISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSRPVDYVNDPHIIAQNDNVVSI
NSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKGGRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTE
FGAVNLKGLSSTERALRIIELAHPDFRDELTQAAKKMHLI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=288, Percent_Identity=28.125, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563853, Length=434, Percent_Identity=35.0230414746544, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17538151, Length=437, Percent_Identity=34.0961098398169, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI21358615, Length=431, Percent_Identity=34.5707656612529, Blast_Score=225, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48384; Mature: 48384

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYF
CCCHHHHHCCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEE
ETAKIAGDTILRYELNNRIKPYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLL
EEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHH
AEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARRFIVEVNQYMPRVQGEAAAIH
HHHHCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
HHHHHHHHHCCCCEEEECHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCC
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSR
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCCCHHCC
PVDYVNDPHIIAQNDNVVSINSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKG
CCCCCCCCEEEECCCCEEEECCEEEEEEECCCCCCCCCCCEECCCCCCEEEHHCHHHCCC
GRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTEFGAVNLKGLSSTERALRIIE
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAHPDFRDELTQAAKKMHLI
HCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIRALYDEKLTTPEEAVSSIASGSHLSMGMFAAEPPALLKALADRATRGDIGDLRVYYF
CCCHHHHHCCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEE
ETAKIAGDTILRYELNNRIKPYSMFVTAVERALIRRGIEDGGRKVVNYVPSNFHQAPRLL
EEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHH
AEEIGIDTFMHTVSPMDCHGYFSLGVGNDYSSRIARSARRFIVEVNQYMPRVQGEAAAIH
HHHHCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ISEVDAIVENHVPLIEMPVRSAIPEYTSISHIIADLVPDGACLQMGVGALPNLVCGVLKD
HHHHHHHHHCCCCEEEECHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCC
RNDLGIHTEVLNPGLVDLIRRGVVTNQRKTLDRGRSVFTFAMGQQEMYEYLNDHPAIFSR
CCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHCCCCEEEEECCHHHHHHHHCCCCCHHCC
PVDYVNDPHIIAQNDNVVSINSTLQIDLTGACNSEHMLGHQYSASGGQLDFVRGAYASKG
CCCCCCCCEEEECCCCEEEECCEEEEEEECCCCCCCCCCCEECCCCCCEEEHHCHHHCCC
GRSIIATPSTAAKGTVSRIIPRIDGPVTTPRIDTHYIVTEFGAVNLKGLSSTERALRIIE
CCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAHPDFRDELTQAAKKMHLI
HCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]