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The map label for this gene is hmsH [H]

Identifier: 153950032

GI number: 153950032

Start: 2449653

End: 2452121

Strand: Reverse

Name: hmsH [H]

Synonym: YpsIP31758_2131

Alternate gene names: 153950032

Gene position: 2452121-2449653 (Counterclockwise)

Preceding gene: 153950594

Following gene: 153950323

Centisome position: 51.92

GC content: 48.08

Gene sequence:

>2469_bases
ATGTATAACGCATTTACAACACTACTGCGCCCGTTGCACTGGCACAGAATGACTTTATTAGCGCTATTTATTTCTGGCTT
TGTCGTTAATCCTGCTATGGCGGATACGCAGTATGACTCATTAATTATTCGTGCCAGAGCCGGTGATACTGCGCCAGTCT
TGGACTATTTACAGGAAGAATCTAAAGCGGGTCCATTGCAGAGTGGGCAGGTTGATGACTGGCTGCAAATTGCAGGTTGG
GCAGGGCGCGATCAAGAAGTGATTGATGTTTATGAACGATATCAATCTTCCATGAATATCTCTTCCAGAGGTTTGGCTTC
TGCCGCTCGAGCTTACCGCAACGAAAAGCGCTGGGATCAGGCTTTGGCCTTGTGGCAAAGCAGCTTAAAGAAAGACCCCA
CCAATCCTGATCTTATCAGCGGTATGATCATGACTCAGGCTGATGCTGGACGCGGTGGGGTTGTTTTAAAACAGGCAACA
GAGTTAGCCGAGCGTGATCCCACGGTACAAAATTACATGACGCTGTCTTATTTAAACCGGGCTACTGACCGTAATTATGA
TGCTTTGCAAGCCTCCAGCGAAGCGGTGCGATTGGCACCAACATCTGAAGAAGTGCTCAAAAATCATCTCGAAATATTAC
AGAGAAACCGTATTGTTGAGCCAGCGTTACGGCTTGCTAAAGAGAACCCAAATTTGGTTTCTGCTGAGCATTATCGCCAA
CTTGAGCGCGATGCTGCTGCGGAACAAGTTCGGATGGCGGTGTTGCCAACGCGCAGCGAAACCGAGCGTTTTGACATAGC
GGATAAGGCGTTAGCGGATTATCAGAATTTATTGACCCGTTGGGGCAAAGATCCAGAGGCACAGGCTGACTACCAACGCG
CACGCATTGACCGATTAGGGGCGTTATTGGTCCGTCATCAGACGGCTGATCTGATCAAAGAGTATGAAGCGATGGAGGCT
GAGGGCTATAAAATGCCTGATTATGCCCGCCGTTGGGCGGCTTCTGCCTATATTGACCGAAGGTTGCCGGAAAAAGCAGC
GCCTATCCTCTCCAGCCTCTATTATTCAGACGGTAAAACCTTCCGTAACAGCGACGATTTGCTTGATGCCGATGATCTTT
ACTATTCACTGAATGAAAGCGAACAACTTGATAAAGCCTACCAATTTGCGGTCAATTATAGCGAGCAAACGCCGTATCAG
GTTGGGGTTTATGGCCTGCCGGGCAAAGAACCGAATGATGATTGGATTGAAGGCCAAACGCTATTGGTTCAATCATTGGT
GGCATTGAATGATCTGCCCACCGCACAAAAAAAATTGGAAGATTTATCCAGTACTGCACCCGCTAATCAGAATTTAAGGA
TCGCATTAGCCAGTATTTATCTGGCCCGGGATTTACCGCGTAAAGCGGAGCAAGAATTGAAGGCCGTGGAATCATTAGCA
CCACGCAGCCTTATTCTGGAACGTGCGCAGGCTGAAACTGCGATGGCGCTACAAGAATGGCATCAGATGGCGTTACTGAC
TGATGATGTGATTAGCCGTTCCCCAGAAGATATCCCCTCTCAAGAATTAGATCGCCAACGTAAAGTCCATAACATGTATG
AACTACGGGTGAGTGGTAACCGCGTTATCTCCTCCAACAGCCCGGTGAGCGGCAATAAAGATTATGGGGTCGAAACTCTC
CTTTACAGCCCACCTATTGCAGAGAATTGGCGCGTATTTGGTGGCGGCAGTTATAACAATGGGCAGTTTGAAGAGGGGAC
GGGGATTAGCCGGATTTTGCGCTTAGGTGGTGAATGGACCTCCCGTGACCATTGGGTTGAAGGGGAAATTTCCAATCAGA
ATTATGGCAATGGCAATAAAGTCGGGGCCCGTTTATCAACCTGGTACGACCTTAATGACCACTGGCGTGTAGGGGGGCAG
GTTGAACGTTTAGCTAAAGACACACCACTACGGGCACTGAAGAATAAAGTGACAGCGAATAGCGCGTCTGCTTATGTTTT
CTGGAAAGCAGATGATAAGCGTGATGCTGAACTTAGCGTGACGCCGTCGCGTTTTTCTGACGGTAACAACCGTTGGGAAT
ATGAATTTAACGGGCGTCAGCGTATCTGGACTGGGCCTTACCTAACGGCAGATTTTAATCTGGGGTTGGCAGCCAGCCAA
AACAGTAAAGAAGATGTGATTTACTACAACCCGAAACGTGATTTTGCTTACGTTCCGGCAGTGACTCTCAATCACATTAT
GTACCGGCGGTACAAAACCATCTGGAGCCAGCAAGTCCAACTGGGTGTGGGAGGGTACTGGGAGAAAAATTACGGTAATG
GCTTGGTGACCACGGCGGGCTATGGCCAACGTGTTCAATGGAATGATGTTATCGATACCGGTGTTGCTGTGGTTTATGAC
AAGCGTCCTTACGATGGTAAACGTGAGCACGATGTTACGCTTTCTTTCGATTTAAATTATCGTTTTTAA

Upstream 100 bases:

>100_bases
CTAAGAATTCCATTTCATCATCATTCCATAATGAAAAATGTACGTTCAGGAAGTCGCTTTCCTTGATCATCAAACAAGTT
GCTGGCTTAAGGGTTATATA

Downstream 100 bases:

>100_bases
GGGAATTGGACCATGGCGAAGCTATTAATTTTTATCAAATCGCTCATTGTTGGGATGATGATCGTGTCCACTATGGGGTG
TGCGGAGAAGCCAACGTTCG

Product: outer membrane protein

Products: NA

Alternate protein names: PGA export protein; Poly-beta-1,6-GlcNAc export protein [H]

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEESKAGPLQSGQVDDWLQIAGW
AGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQAT
ELAERDPTVQNYMTLSYLNRATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLGALLVRHQTADLIKEYEAMEA
EGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKTFRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQ
VGVYGLPGKEPNDDWIEGQTLLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
PRSLILERAQAETAMALQEWHQMALLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGNRVISSNSPVSGNKDYGVETL
LYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWTSRDHWVEGEISNQNYGNGNKVGARLSTWYDLNDHWRVGGQ
VERLAKDTPLRALKNKVTANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAASQ
NSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAGYGQRVQWNDVIDTGVAVVYD
KRPYDGKREHDVTLSFDLNYRF

Sequences:

>Translated_822_residues
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEESKAGPLQSGQVDDWLQIAGW
AGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQAT
ELAERDPTVQNYMTLSYLNRATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLGALLVRHQTADLIKEYEAMEA
EGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKTFRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQ
VGVYGLPGKEPNDDWIEGQTLLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
PRSLILERAQAETAMALQEWHQMALLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGNRVISSNSPVSGNKDYGVETL
LYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWTSRDHWVEGEISNQNYGNGNKVGARLSTWYDLNDHWRVGGQ
VERLAKDTPLRALKNKVTANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAASQ
NSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAGYGQRVQWNDVIDTGVAVVYD
KRPYDGKREHDVTLSFDLNYRF
>Mature_822_residues
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEESKAGPLQSGQVDDWLQIAGW
AGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQAT
ELAERDPTVQNYMTLSYLNRATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLGALLVRHQTADLIKEYEAMEA
EGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKTFRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQ
VGVYGLPGKEPNDDWIEGQTLLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
PRSLILERAQAETAMALQEWHQMALLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGNRVISSNSPVSGNKDYGVETL
LYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWTSRDHWVEGEISNQNYGNGNKVGARLSTWYDLNDHWRVGGQ
VERLAKDTPLRALKNKVTANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAASQ
NSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAGYGQRVQWNDVIDTGVAVVYD
KRPYDGKREHDVTLSFDLNYRF

Specific function: Exports the biofilm adhesin polysaccharide poly-beta- 1,6-N-acetyl-D-glucosamine (PGA) across the outer membrane. The PGA transported seems to be partially N-deacetylated since N- deacetylation of PGA by PgaB is needed for PGA export through the PgaA pori

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1787261, Length=787, Percent_Identity=41.5501905972046, Blast_Score=611, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 93346; Mature: 93346

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
SKAGPLQSGQVDDWLQIAGWAGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQ
HCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQATELAERDPTVQNYMTLSYLNR
HHHHHHHHHCCCCCCHHHHHHHHEEECCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
ATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
HCCCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLG
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALLVRHQTADLIKEYEAMEAEGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
FRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQVGVYGLPGKEPNDDWIEGQT
CCCCCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHCCHH
LLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHC
PRSLILERAQAETAMALQEWHQMALLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEECCC
RVISSNSPVSGNKDYGVETLLYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWT
EEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCC
SRDHWVEGEISNQNYGNGNKVGARLSTWYDLNDHWRVGGQVERLAKDTPLRALKNKVTAN
CCCCEEECEECCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHCCC
SASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAASQ
CCCEEEEEECCCCCCCEEEECCHHCCCCCCEEEEEECCCEEEEECCEEEEECCCCEEECC
NSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAG
CCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCEEEEECC
YGQRVQWNDVIDTGVAVVYDKRPYDGKREHDVTLSFDLNYRF
CCCCEEEHHHHHCCEEEEEECCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
SKAGPLQSGQVDDWLQIAGWAGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQ
HCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQATELAERDPTVQNYMTLSYLNR
HHHHHHHHHCCCCCCHHHHHHHHEEECCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
ATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
HCCCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLG
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALLVRHQTADLIKEYEAMEAEGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
FRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQVGVYGLPGKEPNDDWIEGQT
CCCCCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHCCHH
LLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHC
PRSLILERAQAETAMALQEWHQMALLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEECCC
RVISSNSPVSGNKDYGVETLLYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWT
EEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCC
SRDHWVEGEISNQNYGNGNKVGARLSTWYDLNDHWRVGGQVERLAKDTPLRALKNKVTAN
CCCCEEECEECCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHCCC
SASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAASQ
CCCEEEEEECCCCCCCEEEECCHHCCCCCCEEEEEECCCEEEEECCEEEEECCCCEEECC
NSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAG
CCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCEEEEECC
YGQRVQWNDVIDTGVAVVYDKRPYDGKREHDVTLSFDLNYRF
CCCCEEEHHHHHCCEEEEEECCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]