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The map label for this gene is tmcA [H]

Identifier: 153949487

GI number: 153949487

Start: 1471418

End: 1473469

Strand: Direct

Name: tmcA [H]

Synonym: YpsIP31758_1252

Alternate gene names: 153949487

Gene position: 1471418-1473469 (Clockwise)

Preceding gene: 153949058

Following gene: 153948887

Centisome position: 31.15

GC content: 55.56

Gene sequence:

>2052_bases
ATGACGAATCCAATCGTTGCCAGTCAACCACAGATGGCGCAGCAGGGGATCAGGCGTTTGCTGATCCTCAGTGGTCAGGC
CGATTGGTCACGGCAGCAGGCAATAATGCTACGCCAGCATCTGGCAGGCGATTGGCTATGGTTGAGCGAGCAGCCTCCCG
AAGGCGTCAACAGTATCAGTCCAACAGTGGCAAGAACTCTGTTGGGGCAGGAAAACTTACACGGCGTATTTGATGCAACC
GATGGGTTAAATATAGAAGCGCTAGCCATCGTCGCGGGGACCTTGCGGGCGGGGAGTTGGCTGCTATTGCTGGTGCCTGA
GTGGGATGACTGGCCGCAGCGGCCAGATAAAGACAGTTTGCGCTGGAGTGAGCAACCCGCTCCGATTGTCACAGCGAACT
TTATCCGCCACTTACAGCGCCAGTTTTTGGCTGATCCCGATGTGGTGCTGTGGCAGCAAGATCGGCCACTCATATTGCCA
GCGGTTGGTTCTCGCCCATGTTGGCAGCAGCCAGACGGTTCACCAACCGCACAGCAACAGCATATTCTTCAGCGTCTGAT
GCAGGCAGATAGCGGTATTTGGGTACTGACAGCCGCTCGTGGGCGCGGTAAATCGACACTTGCCGGGATGTTAGTCACCC
ACTGGCAGGGGGCATGTTGGGTGACCGGGCCGGGTAAAGCGGCCACTCAAGTGCTTAATCAACAAGCAGGGGAGCGGGCC
AGATTTTGGGCACCAGACGCACTGTTGGATTATTGCCAACGGCATGATGTCAGTGATATTGACTGGTTGTTGATTGATGA
AGCGGCGGCGATCCCGACACCGCTGTTATCGGCATTATTGGCGTATTTCCCCCGGGCATTATTGACCACCACGGTACAGG
GATATGAGGGCTCGGGGCGTGGTTTTTTACTGAAATTCTGCGCGACACTGGGCGATTGGCATCATTTGACGCTGACGGAT
CCTATCCGCTGGGCCACGGATGATCCCTTGGAACGAGTGATGGATAATGCCATGTTGTTCCATGATGAATTACTCGGCAA
TCATCCCCTACCAAAGCGGCCACCTGCGGCGCAGATCGAAATCACCCTTTATGAACAACGCGATTGGCGAGATAACCCGG
AGTTACTGCGGCGTTTTTATGGCTTACTCTCTACGGCTCATTACCGCACGACGCCGCTGGATTTACGCCGTCTGATGGAT
GCTCCGGGTATGCATTTCTCTGCCGCCAGAGTGGCCGATGCCGTGATTGGCGCATTATGGCTGGTGGATGAAGGGGGATT
GAGCGAGGCACTGGCCCTTGATGTCTGGGCGGGTCGGCGGCGGCCCAGAGGGAATCTGGTGGCACAATCACTGGCCGCTC
ATGGCGGGCAGTGGCAGGCACCAACGCTGTTATCGCGGCGTATCAGCCGGGTCGCTGTCACGGCAGCATGGCGGCAGCAA
GGAATTGCCCGCCGGATGATTGCCGCAGAACAGGCCCATGCCCGCCAGCAGCAGTGTGATTTTCTTTCGGTCAGTTTTGG
CTATACCGCCGAGTTGGCTCATTTTTGGCACCGCTGTGGTTTTCGTTTGGTACGTATTGGTAGCCATAAAGAGGCCAGTA
GCGGTTGTTATACCGCAATGGCGTTGTTACCTCTTAGTCCCGCGGGGGAGGCACTCTGTCAGGCGGCGCAGCAGCAGTTA
AAACGTGATTGGTATTGGTTACAGCAATGGATTGACATACCAACCCCGGTATTTTTACGGCTACCTGAACCGCCGGAGGT
CACGTTAACTGACGACGATTGGCGGGAACTGGCTGGGTTTGCTTTTGCTTTCCGCCCATTAGAGGCCAGTTTACCGGCGC
TACAACGGTTGTTATTACACACCGAGTTACCCCTTTCGGCGTTACGACACTATTTGCAGTTACGCACTCCTCAGTCTGAG
ATTATCAATACCCTTGGTTTGATAGGGCGTAAGGCATTGGTGGCACTGTGGCGTCAGGAAGCCGCCGAGGGGATGGCAAT
GATTGATGTGGATAAAATGGATCATGTCTGCCAAACCATCGGCGCGGTGTAG

Upstream 100 bases:

>100_bases
CTGGTAGGAACGGTGCTCGGCGTCGCCTTGTTCAAAGGCGTCCCTGTCGGGCCATTGATTGCCGCCGGTTTGCTCTCACT
GGTCATAGGCAAGTCGTAAG

Downstream 100 bases:

>100_bases
CACTGTCCGGTTACCCGGTAGAAAAAACCTTACGATATGCCAATGCTAATACCAGCGGTGCGTTAGCGGTTTCGCACAAA
GGCCCAATGGAAGGTTTATC

Product: acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 682

Protein sequence:

>683_residues
MTNPIVASQPQMAQQGIRRLLILSGQADWSRQQAIMLRQHLAGDWLWLSEQPPEGVNSISPTVARTLLGQENLHGVFDAT
DGLNIEALAIVAGTLRAGSWLLLLVPEWDDWPQRPDKDSLRWSEQPAPIVTANFIRHLQRQFLADPDVVLWQQDRPLILP
AVGSRPCWQQPDGSPTAQQQHILQRLMQADSGIWVLTAARGRGKSTLAGMLVTHWQGACWVTGPGKAATQVLNQQAGERA
RFWAPDALLDYCQRHDVSDIDWLLIDEAAAIPTPLLSALLAYFPRALLTTTVQGYEGSGRGFLLKFCATLGDWHHLTLTD
PIRWATDDPLERVMDNAMLFHDELLGNHPLPKRPPAAQIEITLYEQRDWRDNPELLRRFYGLLSTAHYRTTPLDLRRLMD
APGMHFSAARVADAVIGALWLVDEGGLSEALALDVWAGRRRPRGNLVAQSLAAHGGQWQAPTLLSRRISRVAVTAAWRQQ
GIARRMIAAEQAHARQQQCDFLSVSFGYTAELAHFWHRCGFRLVRIGSHKEASSGCYTAMALLPLSPAGEALCQAAQQQL
KRDWYWLQQWIDIPTPVFLRLPEPPEVTLTDDDWRELAGFAFAFRPLEASLPALQRLLLHTELPLSALRHYLQLRTPQSE
IINTLGLIGRKALVALWRQEAAEGMAMIDVDKMDHVCQTIGAV

Sequences:

>Translated_683_residues
MTNPIVASQPQMAQQGIRRLLILSGQADWSRQQAIMLRQHLAGDWLWLSEQPPEGVNSISPTVARTLLGQENLHGVFDAT
DGLNIEALAIVAGTLRAGSWLLLLVPEWDDWPQRPDKDSLRWSEQPAPIVTANFIRHLQRQFLADPDVVLWQQDRPLILP
AVGSRPCWQQPDGSPTAQQQHILQRLMQADSGIWVLTAARGRGKSTLAGMLVTHWQGACWVTGPGKAATQVLNQQAGERA
RFWAPDALLDYCQRHDVSDIDWLLIDEAAAIPTPLLSALLAYFPRALLTTTVQGYEGSGRGFLLKFCATLGDWHHLTLTD
PIRWATDDPLERVMDNAMLFHDELLGNHPLPKRPPAAQIEITLYEQRDWRDNPELLRRFYGLLSTAHYRTTPLDLRRLMD
APGMHFSAARVADAVIGALWLVDEGGLSEALALDVWAGRRRPRGNLVAQSLAAHGGQWQAPTLLSRRISRVAVTAAWRQQ
GIARRMIAAEQAHARQQQCDFLSVSFGYTAELAHFWHRCGFRLVRIGSHKEASSGCYTAMALLPLSPAGEALCQAAQQQL
KRDWYWLQQWIDIPTPVFLRLPEPPEVTLTDDDWRELAGFAFAFRPLEASLPALQRLLLHTELPLSALRHYLQLRTPQSE
IINTLGLIGRKALVALWRQEAAEGMAMIDVDKMDHVCQTIGAV
>Mature_682_residues
TNPIVASQPQMAQQGIRRLLILSGQADWSRQQAIMLRQHLAGDWLWLSEQPPEGVNSISPTVARTLLGQENLHGVFDATD
GLNIEALAIVAGTLRAGSWLLLLVPEWDDWPQRPDKDSLRWSEQPAPIVTANFIRHLQRQFLADPDVVLWQQDRPLILPA
VGSRPCWQQPDGSPTAQQQHILQRLMQADSGIWVLTAARGRGKSTLAGMLVTHWQGACWVTGPGKAATQVLNQQAGERAR
FWAPDALLDYCQRHDVSDIDWLLIDEAAAIPTPLLSALLAYFPRALLTTTVQGYEGSGRGFLLKFCATLGDWHHLTLTDP
IRWATDDPLERVMDNAMLFHDELLGNHPLPKRPPAAQIEITLYEQRDWRDNPELLRRFYGLLSTAHYRTTPLDLRRLMDA
PGMHFSAARVADAVIGALWLVDEGGLSEALALDVWAGRRRPRGNLVAQSLAAHGGQWQAPTLLSRRISRVAVTAAWRQQG
IARRMIAAEQAHARQQQCDFLSVSFGYTAELAHFWHRCGFRLVRIGSHKEASSGCYTAMALLPLSPAGEALCQAAQQQLK
RDWYWLQQWIDIPTPVFLRLPEPPEVTLTDDDWRELAGFAFAFRPLEASLPALQRLLLHTELPLSALRHYLQLRTPQSEI
INTLGLIGRKALVALWRQEAAEGMAMIDVDKMDHVCQTIGAV

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788818, Length=662, Percent_Identity=51.6616314199396, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17507621, Length=362, Percent_Identity=24.8618784530387, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640662, Length=341, Percent_Identity=24.3401759530792, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 76490; Mature: 76358

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPIVASQPQMAQQGIRRLLILSGQADWSRQQAIMLRQHLAGDWLWLSEQPPEGVNSIS
CCCCCCCCCCHHHHHHHHHEEHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCC
PTVARTLLGQENLHGVFDATDGLNIEALAIVAGTLRAGSWLLLLVPEWDDWPQRPDKDSL
HHHHHHHHCCCCCCEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
RWSEQPAPIVTANFIRHLQRQFLADPDVVLWQQDRPLILPAVGSRPCWQQPDGSPTAQQQ
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCHHHH
HILQRLMQADSGIWVLTAARGRGKSTLAGMLVTHWQGACWVTGPGKAATQVLNQQAGERA
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCC
RFWAPDALLDYCQRHDVSDIDWLLIDEAAAIPTPLLSALLAYFPRALLTTTVQGYEGSGR
CCCCCHHHHHHHHHCCCCCCCEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GFLLKFCATLGDWHHLTLTDPIRWATDDPLERVMDNAMLFHDELLGNHPLPKRPPAAQIE
HHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
ITLYEQRDWRDNPELLRRFYGLLSTAHYRTTPLDLRRLMDAPGMHFSAARVADAVIGALW
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LVDEGGLSEALALDVWAGRRRPRGNLVAQSLAAHGGQWQAPTLLSRRISRVAVTAAWRQQ
EECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GIARRMIAAEQAHARQQQCDFLSVSFGYTAELAHFWHRCGFRLVRIGSHKEASSGCYTAM
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHH
ALLPLSPAGEALCQAAQQQLKRDWYWLQQWIDIPTPVFLRLPEPPEVTLTDDDWRELAGF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCHHHHHHHHH
AFAFRPLEASLPALQRLLLHTELPLSALRHYLQLRTPQSEIINTLGLIGRKALVALWRQE
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAEGMAMIDVDKMDHVCQTIGAV
HHCCCEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNPIVASQPQMAQQGIRRLLILSGQADWSRQQAIMLRQHLAGDWLWLSEQPPEGVNSIS
CCCCCCCCCHHHHHHHHHEEHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCC
PTVARTLLGQENLHGVFDATDGLNIEALAIVAGTLRAGSWLLLLVPEWDDWPQRPDKDSL
HHHHHHHHCCCCCCEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
RWSEQPAPIVTANFIRHLQRQFLADPDVVLWQQDRPLILPAVGSRPCWQQPDGSPTAQQQ
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCHHHH
HILQRLMQADSGIWVLTAARGRGKSTLAGMLVTHWQGACWVTGPGKAATQVLNQQAGERA
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCC
RFWAPDALLDYCQRHDVSDIDWLLIDEAAAIPTPLLSALLAYFPRALLTTTVQGYEGSGR
CCCCCHHHHHHHHHCCCCCCCEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GFLLKFCATLGDWHHLTLTDPIRWATDDPLERVMDNAMLFHDELLGNHPLPKRPPAAQIE
HHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
ITLYEQRDWRDNPELLRRFYGLLSTAHYRTTPLDLRRLMDAPGMHFSAARVADAVIGALW
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LVDEGGLSEALALDVWAGRRRPRGNLVAQSLAAHGGQWQAPTLLSRRISRVAVTAAWRQQ
EECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GIARRMIAAEQAHARQQQCDFLSVSFGYTAELAHFWHRCGFRLVRIGSHKEASSGCYTAM
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHH
ALLPLSPAGEALCQAAQQQLKRDWYWLQQWIDIPTPVFLRLPEPPEVTLTDDDWRELAGF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCHHHHHHHHH
AFAFRPLEASLPALQRLLLHTELPLSALRHYLQLRTPQSEIINTLGLIGRKALVALWRQE
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAEGMAMIDVDKMDHVCQTIGAV
HHCCCEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA