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The map label for this gene is xseA [H]

Identifier: 153949399

GI number: 153949399

Start: 1404750

End: 1406126

Strand: Reverse

Name: xseA [H]

Synonym: YpsIP31758_1193

Alternate gene names: 153949399

Gene position: 1406126-1404750 (Counterclockwise)

Preceding gene: 153949238

Following gene: 153949449

Centisome position: 29.77

GC content: 52.21

Gene sequence:

>1377_bases
ATGTCGCAATCTTCCGCCTCCTCAATTTTTACTGTCAGCCGCCTGAATCAGACGGTACGAGAACTATTGGAAAGGGAAAT
GGGCCAGATTTGGCTCACTGCCGAGATTTCTAATTTCTCTCAGCCCGCTTCTGGGCACTGGTATTTCACGCTGAAAGATG
ATCGGGCGCAAGTGCGCTGTGCCATGTTTCGTAACAGCAACCGCCGCACCACTTTCCGTCCGCAGAATGGCCAACAAGTT
TTGGTCAGGGCATCAATTACCCTGTATGAACCCCGTGGTGATTATCAGTTAATTGCGGAAAGTATGCAGCCTGCCGGTGA
TGGGTTGCTGCAACAACAATTTGAACAGCTTAAGCAACAATTAGCGGCCGAAGGGCTGTTTGATCAAAGCCACAAACAGC
CACTCCCTCGCCCCGCCAAACAAGTGGGCGTAATAACGTCTGCCAGTGGGGCTGCGCTGCATGATGTACTGCATGTGTTA
CAGCGCCGTGATCCATCGCTTCCAGTAATTATTTATCCCACATCAGTACAGGGCGTTGATGCGCCATTGCAGATAGTCCG
TGCGATCCAGTTGGCGAACTTACGTGCTGAATGCGATGTATTGATTGTTGGCCGCGGTGGCGGATCGCTAGAAGATTTGT
GGAGTTTCAACGACGAACGGGTTGCCCGCGCTATCTTTAACAGCCATATCCCTATCGTCAGCGCTGTCGGCCATGAAACC
GATGTCACTATTGCCGATTTTGTTGCTGATTTACGCGCCCCAACCCCTTCGGCTGCCGCCGAGCTAGTCAGTCGCAATCA
GATTGAGCTCGTTCGTCAGATTCAAGGGCAACAGCAACGAATGGAAATGGCGATGGATTACTATCTGGCGCAACGCAACC
AGCAATTCACCCGCCTTGAACACCGTTTGCAGCAACAGCATCCGCATTTACGTTTAGCCCGTCAGCAAACATTGTTGCTG
AAATTACAACGTAGGCTGGAAGAGAGTGCACAAACACAGATCCGCTTATTAAGTAAACGTACCGAGCGGCTGCAACAGCG
TTTGCAGCAAGTGCAGCCTCAGGGGCAAATTCACCGGTATAACCAGCGGGTACAGCAGCAAGAATACCGTTTACGTCAAG
CTGTAGAGCGCCAGCTCAATGGCTATCGCCAACGCTTTGGTATCGCCTGCTCCCAGCTAGAGGCCGTGAGCCCACTGGCA
ACACTGGCCCGTGGCTACAGCGTGACACAGACGCCAGCAGGGGCGTTATTGAAGACCACCAAGCAAGTACAGGCCGGTGA
TAAACTGACCACCCGGTTGCAAGACGGTTGGGTGGAAAGTGAGATTACCCAAGTCACCGTAGCGAAGAAAAGCCGTCAGA
AAAAAGTAGTGACGTAG

Upstream 100 bases:

>100_bases
GATTGCCTCCAGCACTTTCTCATAATATTTCTTGCCAACCAGTTTGAGGCAGGTAATATCGGTTAATTAAGTCCTTGTTT
TAAAATTTGATCCAGGTCAC

Downstream 100 bases:

>100_bases
TCATTATAGCGGCAAGGATGGGGCTGCCAGTAAAACCATCAGCCTCTAACACTCTTTCGTTGATCATTTCCCCACCTGAT
AAGCCGTCAGCTTACCGGTA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQV
LVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPRPAKQVGVITSASGAALHDVLHVL
QRRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLL
KLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLA
TLARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVT

Sequences:

>Translated_458_residues
MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQV
LVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPRPAKQVGVITSASGAALHDVLHVL
QRRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLL
KLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLA
TLARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVT
>Mature_457_residues
SQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQVL
VRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPRPAKQVGVITSASGAALHDVLHVLQ
RRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHETD
VTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLLK
LQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLAT
LARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVT

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=454, Percent_Identity=71.8061674008811, Blast_Score=667, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 51990; Mature: 51859

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRC
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEEECCCHHHHH
AMFRNSNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQ
HHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LAAEGLFDQSHKQPLPRPAKQVGVITSASGAALHDVLHVLQRRDPSLPVIIYPTSVQGVD
HHHHCCCCCCCCCCCCCCHHHHCCEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCC
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLE
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HRLQQQHPHLRLARQQTLLLKLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPAGALLKTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVT
HHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRC
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEEECCCHHHHH
AMFRNSNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQ
HHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LAAEGLFDQSHKQPLPRPAKQVGVITSASGAALHDVLHVLQRRDPSLPVIIYPTSVQGVD
HHHHCCCCCCCCCCCCCCHHHHCCEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHET
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCC
DVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLE
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HRLQQQHPHLRLARQQTLLLKLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPAGALLKTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVT
HHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA