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The map label for this gene is aroB

Identifier: 153949291

GI number: 153949291

Start: 4447414

End: 4448502

Strand: Reverse

Name: aroB

Synonym: YpsIP31758_3965

Alternate gene names: 153949291

Gene position: 4448502-4447414 (Counterclockwise)

Preceding gene: 153949876

Following gene: 153949832

Centisome position: 94.18

GC content: 49.86

Gene sequence:

>1089_bases
ATGGAGAAGATTACTGTCACGTTAGGGGAACGTAGCTACCCCATTACGATTGCCGCCGGGTTGTTTAATGATCCGGCCTC
TTTTAAGCCGCTAAAGGCGGGTGACCAGGTTATGCTGGTCACTAACCAAACGTTGGCTCCGCTCTATCTGGATTCTCTCC
GGGCAGTGTTGGAACACGGTGGCATTAAAGTTGATCAGGTGATTTTACCTGATGGTGAGCAGTATAAATCTCTGAGCGTT
ATGGAGCAGGTTTTTTCTGCCCTTCTGGAAAAACCGCACGGTCGTGATACTACGTTGGTTGCCTTAGGTGGCGGCGTAGT
GGGCGACCTGACCGGTTTTGCCGCAGCTTGCTATCAACGCGGTGTGCGCTTTATTCAAGTTCCTACTACTTTACTTTCTC
AAGTGGATTCTTCTGTTGGTGGTAAAACCGCCGTTAACCATCCCTTGGGTAAAAATATGATTGGTGCCTTCTACCAGCCT
GCATCGGTGGTGGTTGATCTTAATTGTCTTAAAACTCTCCCCCCGCGTGAACTCGCTTCTGGCTTGGCTGAAGTGATCAA
ATACGGCATCATCCTTGATGCAGCTTTCTTCGATTGGTTAGAAAACAACATTGACGCTTTATTAGCGCTGGATATGTCAG
CATTAGCTTACTGTATTCGCCGCTGTTGCGAATTAAAGGCCGATGTCGTTGCTGCTGATGAACGCGAAGAGAGCGGTGCG
CGCGCTTTACTCAATTTGGGTCACACCTATGGTCATGCTATCGAAGCTGAAATGGGCTACGGAGTGTGGTTACACGGTGA
AGCGGTTGCTGCTGGGATGGTGATGGCCGCACAGACATCCCGTCGTCTGGGGCAACTCTCTGTCAGTGATGTTGAGCGTA
TCAAGAAACTCCTATTACGTGCTGGTCTACCCGTTTGTGGGCCTAAAGAAATGGCACCAGAATCTTATCTGCCACACATG
ATGCGGGATAAAAAAGTATTGGCGGGTGAACTTCGTCTGGTACTGCCAACGGCCATCGGTAAATCAGAAATCCGGGGCGG
TGTTGCGCATGATATGGTGTTGGCATCGATAGCGGATTGTCGGCCATAG

Upstream 100 bases:

>100_bases
AAGTGGTTGCTAACCAGATTATCAACATGCTGGAAAGTAACTGATTTTATCATTTTACTAATGCCTACGGGCGTAAGTTA
AGAAGGTTACAGAGCGCGAC

Downstream 100 bases:

>100_bases
AAAATGGCATAGATGTGATATTTCATAAGAATTATGTTTCATAAAAACTATGCTCATCAGTGTTCTTTTCATCAGAACCC
TGTTCACAAGTGCTATGCTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MEKITVTLGERSYPITIAAGLFNDPASFKPLKAGDQVMLVTNQTLAPLYLDSLRAVLEHGGIKVDQVILPDGEQYKSLSV
MEQVFSALLEKPHGRDTTLVALGGGVVGDLTGFAAACYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLNCLKTLPPRELASGLAEVIKYGIILDAAFFDWLENNIDALLALDMSALAYCIRRCCELKADVVAADEREESGA
RALLNLGHTYGHAIEAEMGYGVWLHGEAVAAGMVMAAQTSRRLGQLSVSDVERIKKLLLRAGLPVCGPKEMAPESYLPHM
MRDKKVLAGELRLVLPTAIGKSEIRGGVAHDMVLASIADCRP

Sequences:

>Translated_362_residues
MEKITVTLGERSYPITIAAGLFNDPASFKPLKAGDQVMLVTNQTLAPLYLDSLRAVLEHGGIKVDQVILPDGEQYKSLSV
MEQVFSALLEKPHGRDTTLVALGGGVVGDLTGFAAACYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLNCLKTLPPRELASGLAEVIKYGIILDAAFFDWLENNIDALLALDMSALAYCIRRCCELKADVVAADEREESGA
RALLNLGHTYGHAIEAEMGYGVWLHGEAVAAGMVMAAQTSRRLGQLSVSDVERIKKLLLRAGLPVCGPKEMAPESYLPHM
MRDKKVLAGELRLVLPTAIGKSEIRGGVAHDMVLASIADCRP
>Mature_362_residues
MEKITVTLGERSYPITIAAGLFNDPASFKPLKAGDQVMLVTNQTLAPLYLDSLRAVLEHGGIKVDQVILPDGEQYKSLSV
MEQVFSALLEKPHGRDTTLVALGGGVVGDLTGFAAACYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLNCLKTLPPRELASGLAEVIKYGIILDAAFFDWLENNIDALLALDMSALAYCIRRCCELKADVVAADEREESGA
RALLNLGHTYGHAIEAEMGYGVWLHGEAVAAGMVMAAQTSRRLGQLSVSDVERIKKLLLRAGLPVCGPKEMAPESYLPHM
MRDKKVLAGELRLVLPTAIGKSEIRGGVAHDMVLASIADCRP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=361, Percent_Identity=81.4404432132964, Blast_Score=594, Evalue=1e-171,
Organism=Saccharomyces cerevisiae, GI6320332, Length=341, Percent_Identity=39.8826979472141, Blast_Score=205, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_YERP3 (A7FNT5)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402913.1
- ProteinModelPortal:   A7FNT5
- SMR:   A7FNT5
- STRING:   A7FNT5
- GeneID:   5384485
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3965
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- BioCyc:   YPSE349747:YPSIP31758_3965-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38838; Mature: 38838

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKITVTLGERSYPITIAAGLFNDPASFKPLKAGDQVMLVTNQTLAPLYLDSLRAVLEHG
CCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHC
GIKVDQVILPDGEQYKSLSVMEQVFSALLEKPHGRDTTLVALGGGVVGDLTGFAAACYQR
CCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLNCLKTLPPRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEHHHCCCCHHHHHH
GLAEVIKYGIILDAAFFDWLENNIDALLALDMSALAYCIRRCCELKADVVAADEREESGA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHH
RALLNLGHTYGHAIEAEMGYGVWLHGEAVAAGMVMAAQTSRRLGQLSVSDVERIKKLLLR
HHHHHHCCHHCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AGLPVCGPKEMAPESYLPHMMRDKKVLAGELRLVLPTAIGKSEIRGGVAHDMVLASIADC
CCCCCCCCHHCCCHHHCHHHHHCCHHHHHHHEEEEECCCCHHHHCCCHHHHHHHHHHHCC
RP
CC
>Mature Secondary Structure
MEKITVTLGERSYPITIAAGLFNDPASFKPLKAGDQVMLVTNQTLAPLYLDSLRAVLEHG
CCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHC
GIKVDQVILPDGEQYKSLSVMEQVFSALLEKPHGRDTTLVALGGGVVGDLTGFAAACYQR
CCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLNCLKTLPPRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEHHHCCCCHHHHHH
GLAEVIKYGIILDAAFFDWLENNIDALLALDMSALAYCIRRCCELKADVVAADEREESGA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHH
RALLNLGHTYGHAIEAEMGYGVWLHGEAVAAGMVMAAQTSRRLGQLSVSDVERIKKLLLR
HHHHHHCCHHCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AGLPVCGPKEMAPESYLPHMMRDKKVLAGELRLVLPTAIGKSEIRGGVAHDMVLASIADC
CCCCCCCCHHCCCHHHCHHHHHCCHHHHHHHEEEEECCCCHHHHCCCHHHHHHHHHHHCC
RP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA