Click here to switch to the map view.

The map label for this gene is dalD [H]

Identifier: 153949185

GI number: 153949185

Start: 2093031

End: 2094422

Strand: Reverse

Name: dalD [H]

Synonym: YpsIP31758_1812

Alternate gene names: 153949185

Gene position: 2094422-2093031 (Counterclockwise)

Preceding gene: 153947594

Following gene: 153947549

Centisome position: 44.34

GC content: 50.29

Gene sequence:

>1392_bases
ATGAATACTGACCTGAAATCACCCCCTGCTGTGTGGCTGCATATTGGTGCTGGCTCCTTCCACCGAGCCCATCAGGCTTG
GTATTTACACCGTTTGTTAGCCTCAGGCGATGACCGTTGGACTATCGCTTTGGCCAATATTCGTGATGACGCCATCCCAC
TACTGGACACATTGCGGGCGCAACACGGTGAATATGTCTTGGAAACGGTCACACCAAGCGGTGAACGCCAGTATGAAAAG
ATAACATCACTGCGCAATATCATTCCTTGGGATAAAGCGCTAGATCATCTGGTAGCGCAAGGGAGTAAACCCGAAACTCG
CGTGATCTCTTTCACCGTAACGGAGGGGGGCTACTATTTAGATAATCAATTTAATCTGCAACAGGACAATAGCGATATTC
AGGCCGATCTTAGAGGAGATTGCCGCACGATTTACGGGGCAATTAGCCGTATCTTGCAACAACGGCAACAGGATAAGAGT
GGCCCGGTCACTCTACTGAACTGCGATAACTTGCGTCACAACGGTGAACGATTCCGCCATGGCTTATTAGAGTTTCTTGC
TCTACGAGGTCAACAAAGCCTATTAAACTGGGTGACAAACCAGACCCGCAGCCCGAATACCATGGTTGATCGTATCACCC
CGCGCCCATCAGCCGATATCGCGCAGCGGGTGTTGGAAAAAACCGGTATCGTAGATAACGCTCCGGTGATGGGGGAATCA
TTTATTCAATGGGTTATTGAGGATGATTTTATTGCTGGCCGCCCGGCACTGGAGAACGTTGGGGCGGAAATGGTCACCTC
GGTTTTGCCTTATGAAGAAGCCAAAATCCGCATTCTGAACGCCAGCCACAGTTGTATTGCTTGGGCGGGCAGCTTGATTG
GGCAATGTTATATTCATGAAAGTACCCAAACCGACGCTATCCGCCAGATGGCTTATGACTATGTCACGCAAGATGTCATT
CCCTCCCTGACGCCCAGCCCACTTGATTTAGCCCATTACCGCGATGTGGTACTGGAACGTTTCAGTAATCCGTATATTCG
CGATACGAACCAGCGTGTCGCCGCCGATGGATTTTCCAAAATCCCCGGATTTATCACTCCCACGCTGATCGAGTGTTACC
AACGTGGCGGAGTGCCTACCGCTACCGCAATGTTGCCCGCATTATTCTTCGTATTTATGGAAAGTTGGCACCAAGGCACT
CTGCCGTATGAATATCAGGATGGTATTCTGGACCCAGCAGCCGTCCATGCCATGTTTCAGTCTTCTGACCCTGCAGGCTT
ATTTGCCCGTGATAGCGCCCTTTTCGGGCCGCTGGCCAATGATGATCAGTTCGAACAGTTATTACGCCAGTCCATAAATC
GTGTCTCTGCTTGGGTTAGCACTAACCGTTAA

Upstream 100 bases:

>100_bases
GGCAAAAGTTACATTAACCTACACGAAAGGGCAAATGCCCAAATATTGAATTTATGCCCAAACAATAACTGTAGCACCTT
CTGTAATTGTGGAGATTATT

Downstream 100 bases:

>100_bases
TCCCTGAGGAGGGGCTTGGGGGGGCGGCGCGTTTAGGGGGCTGGGGATCTCCGGTGATAAATGATCGTCAGTAATTAATG
ATCTGCCGTAATTAACGATC

Product: D-arabinitol 4-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRAQHGEYVLETVTPSGERQYEK
ITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQQDKS
GPVTLLNCDNLRHNGERFRHGLLEFLALRGQQSLLNWVTNQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPVMGES
FIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHESTQTDAIRQMAYDYVTQDVI
PSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESWHQGT
LPYEYQDGILDPAAVHAMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR

Sequences:

>Translated_463_residues
MNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRAQHGEYVLETVTPSGERQYEK
ITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQQDKS
GPVTLLNCDNLRHNGERFRHGLLEFLALRGQQSLLNWVTNQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPVMGES
FIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHESTQTDAIRQMAYDYVTQDVI
PSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESWHQGT
LPYEYQDGILDPAAVHAMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR
>Mature_463_residues
MNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRAQHGEYVLETVTPSGERQYEK
ITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQQDKS
GPVTLLNCDNLRHNGERFRHGLLEFLALRGQQSLLNWVTNQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPVMGES
FIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHESTQTDAIRQMAYDYVTQDVI
PSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESWHQGT
LPYEYQDGILDPAAVHAMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790779, Length=374, Percent_Identity=34.4919786096257, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1788497, Length=356, Percent_Identity=33.1460674157303, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787823, Length=360, Percent_Identity=32.5, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI48994885, Length=414, Percent_Identity=22.2222222222222, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790028, Length=365, Percent_Identity=23.2876712328767, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324401, Length=456, Percent_Identity=32.6754385964912, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320765, Length=456, Percent_Identity=32.6754385964912, Blast_Score=225, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.11 [H]

Molecular weight: Translated: 52012; Mature: 52012

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRA
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
QHGEYVLETVTPSGERQYEKITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYL
HCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCEEE
DNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQQDKSGPVTLLNCDNLRHNGERFRH
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
GLLEFLALRGQQSLLNWVTNQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPVMGES
HHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHH
FIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHEEEEC
STQTDAIRQMAYDYVTQDVIPSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHCCHHH
IPGFITPTLIECYQRGGVPTATAMLPALFFVFMESWHQGTLPYEYQDGILDPAAVHAMFQ
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHC
SSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR
CCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRA
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
QHGEYVLETVTPSGERQYEKITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYL
HCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCEEE
DNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQQDKSGPVTLLNCDNLRHNGERFRH
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
GLLEFLALRGQQSLLNWVTNQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPVMGES
HHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHH
FIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHEEEEC
STQTDAIRQMAYDYVTQDVIPSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHCCHHH
IPGFITPTLIECYQRGGVPTATAMLPALFFVFMESWHQGTLPYEYQDGILDPAAVHAMFQ
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHC
SSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR
CCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]