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The map label for this gene is dapB

Identifier: 153948962

GI number: 153948962

Start: 3894602

End: 3895423

Strand: Reverse

Name: dapB

Synonym: YpsIP31758_3455

Alternate gene names: 153948962

Gene position: 3895423-3894602 (Counterclockwise)

Preceding gene: 153950001

Following gene: 153948324

Centisome position: 82.47

GC content: 50.0

Gene sequence:

>822_bases
ATGACTGATTCAACAATTCGTATTGCTATTGTCGGCGCGGGTGGACGGATGGGGCGGCAATTAATTCAAGCCGTTACGCA
GATGGAAGGCGTTGTCTTAGGGGCGGCTATCGAGCGTAAAGGGTCCACGTTGGTAGGCAGTGATGCGGGTGAGCTGGCGG
GTGTTGGCTTGTTAAATGTCATTGTCGGCGATGATTTATCCCAACTTACTGATAATTTTGACGTACTGATCGACTTTACC
CGCCCAGAAGGTACGTTGGAACATTTAGCTATTTGCCGTCAGCATCGGAAAGCGATGGTGATTGGTACCACGGGTTTTGA
TGAGGCAGGTAAAGCGGCCATTAGTGAGGCTGCGGCAGATATTGGTATTGTATTCGCAGCGAACTTCAGTGTTGGGGTGA
ATGTGGTACTGAAATTGCTGGAAAAGGCGGCGAAAGTCATGGGCGATTATACCGATATTGAAATTATCGAAGCCCATCAC
CGCCACAAAGTGGATGCACCATCAGGAACGGCGCTGGCAATGGGTGAGGCGATTGCTGATGCTATGGGGCGCTCCTTGAA
AGATTGTGCAGTTTATAGCCGTGAAGGCTATACCGGTGAGCGTAAACCGGGGACCATCGGTTTCGCGACCGTGCGTGCTG
GCGATATTGTGGGTGAACACACGGCAATGTTTGCTGATATCGGCGAACGGGTTGAGATCACTCACAAAGCGACGAGCCGG
ATGACTTTTGCCCATGGTGCGGTTAAGTCTACCATTTGGCTTGGTAAGCATGATAATGGCTTGTTTGATATGCGTGATGT
ACTGAATCTTAACGAACTTTAA

Upstream 100 bases:

>100_bases
ATCATTTTTTTCTAATACAGATTAAATAGGCTGGTAGAGTCAATAGCCGGCGGCTAATCTGAACCCTGGTCAGGGTAGAG
GACACATTTTAAGGGGACGT

Downstream 100 bases:

>100_bases
TGCTGTAAATTACGACCAGTGATGTGGTTGTTTTTATCATAATCATTTGATAATAGGGCAATGTTTTATTGTCCTTTTTT
ATTTTAAATTTAAAATAAGC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFT
RPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHH
RHKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
MTFAHGAVKSTIWLGKHDNGLFDMRDVLNLNEL

Sequences:

>Translated_273_residues
MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFT
RPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHH
RHKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
MTFAHGAVKSTIWLGKHDNGLFDMRDVLNLNEL
>Mature_272_residues
TDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFTR
PEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHR
HKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSRM
TFAHGAVKSTIWLGKHDNGLFDMRDVLNLNEL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=273, Percent_Identity=79.1208791208791, Blast_Score=419, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_YERP3 (A7FMD2)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402410.1
- ProteinModelPortal:   A7FMD2
- SMR:   A7FMD2
- STRING:   A7FMD2
- GeneID:   5388137
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3455
- NMPDR:   fig|349747.3.peg.3259
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   YPSE349747:YPSIP31758_3455-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28918; Mature: 28787

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNV
CCCCEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEEHHCCCCEEECCCCCHHHHHHHEEE
IVGDDLSQLTDNFDVLIDFTRPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAAD
ECCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHC
IGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAD
EEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
HHCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHCHHHHHHHHCCCEEEEEEHHHHH
MTFAHGAVKSTIWLGKHDNGLFDMRDVLNLNEL
EEHHHCCHHHEEEECCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNV
CCCEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEEHHCCCCEEECCCCCHHHHHHHEEE
IVGDDLSQLTDNFDVLIDFTRPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAAD
ECCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHC
IGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAD
EEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
HHCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHCHHHHHHHHCCCEEEEEEHHHHH
MTFAHGAVKSTIWLGKHDNGLFDMRDVLNLNEL
EEHHHCCHHHEEEECCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA