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The map label for this gene is ureH [H]

Identifier: 153948871

GI number: 153948871

Start: 1289228

End: 1290286

Strand: Direct

Name: ureH [H]

Synonym: YpsIP31758_1085

Alternate gene names: 153948871

Gene position: 1289228-1290286 (Clockwise)

Preceding gene: 153948186

Following gene: 153949502

Centisome position: 27.3

GC content: 41.27

Gene sequence:

>1059_bases
ATGACGACAATAATCGCCAGCAGCAGCGCCTTTGGTAATCAGCAAACAAAGCGCAGAGCCATCTACCTGCTAATCGGCCT
GTTGGTGGTGAATGGGTTAGCTTGGGTCTGGGCTTTTGCTGAATTTAATGATAATGCCGTGCTGATGGGAATGGCTTTCC
TGGCCTACAGTTTTGGTTTGCGCCATGCGGTTGATGCGGATCATATTGCGGCTATTGATAACGTCACGCGTAAACTCATG
CAACAAGGTAAAACACCGATTGCTGTTGGGACTTTTTTCTCACTCGGCCATTCAACTATTGTGATCTTAGCTTCACTGGC
AATTGCTGCGACCGCCATGGCATTTAAGAATAATATGGCGTGGTTTCACGAAACCGGTGGTTTAATCGGGACGTTGGTGT
CATCCATTTTTTTATTGTTATTTGCTTTTCTCAATTTAACGATCCTGATTTCAGTGTATAAAAAATTCAAACAAGTTAAA
GCTGGGCATATTTATAAAGATGAAGAGCTTGACCTTCTGGTCGTGAATAATGGTGGTCTGTTATCCAGAATGTTTAAACG
TGTCTTTAATATGGTTAATAAAAGCTGGCATATGTATCCAGTTGGTTTTTTGTTTGGTTTAGGTTTTGATACCGCAACTG
AAATTGGTGTTTTGGGGATATCAGCGGCCAGCGCCACTCACGGTATGAATTTGTGGTCGATAATGGTGTTTCCGATTTTA
TTTGCGGCCGGAATGGCATTGATCGATTCACTGGATAATTTTGTGATGATTGGTGCTTATGGCTGGGCATTTTCTAAACC
TGTTCGTAAACTTTATTACAATATCACTATCACCGCCGCGTCGGTGATTATTGCTTTCTTTATCGGTGGCATTGAAGCCT
TGGGTTTGATTGCCGATAAGTTAAATTTAACTGGTGGTATCTGGACGCCAATTAATAATATCAGCGAGAACTTAGGTCAG
ATCGGTTACTGGATTATAGGGATGTTTATATGTTGCTGGTTAGTTTCTATTATTAATTACTATGTCCGTGGTTATGACAA
GCTAAATATAAGCCGCTAA

Upstream 100 bases:

>100_bases
TTTATCGATCATATAGACCTCAAATTATTGGCGTTATCGTGTTGTCAGCGATAACGCCAGGTCAGAACGGGTAGGGTTGA
AAATAATCTGGAGTGCGAAT

Downstream 100 bases:

>100_bases
GTCATATTTGTTGCGAGTGAATTATTAGACCCGCTGACACAATAATTTGTAATTGCGTTGGTTAGGGAAGGCTAACAAAT
AGAGACACTCATTAACCGAT

Product: high-affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAIDNVTRKLM
QQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSIFLLLFAFLNLTILISVYKKFKQVK
AGHIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPINNISENLGQ
IGYWIIGMFICCWLVSIINYYVRGYDKLNISR

Sequences:

>Translated_352_residues
MTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAIDNVTRKLM
QQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSIFLLLFAFLNLTILISVYKKFKQVK
AGHIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPINNISENLGQ
IGYWIIGMFICCWLVSIINYYVRGYDKLNISR
>Mature_351_residues
TTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAIDNVTRKLMQ
QGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSIFLLLFAFLNLTILISVYKKFKQVKA
GHIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPILF
AAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPINNISENLGQI
GYWIIGMFICCWLVSIINYYVRGYDKLNISR

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 38694; Mature: 38563

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGL
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RHAVDADHIAAIDNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMA
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
WFHETGGLIGTLVSSIFLLLFAFLNLTILISVYKKFKQVKAGHIYKDEELDLLVVNNGGL
EEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCH
LSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
HHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCHHHHHEEEEEHHHHHCCCHHHHHHHHHHH
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADK
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLTGGIWTPINNISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGL
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RHAVDADHIAAIDNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMA
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
WFHETGGLIGTLVSSIFLLLFAFLNLTILISVYKKFKQVKAGHIYKDEELDLLVVNNGGL
EEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCH
LSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
HHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCHHHHHEEEEEHHHHHCCCHHHHHHHHHHH
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADK
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLTGGIWTPINNISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]