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The map label for this gene is baeS [H]

Identifier: 153948841

GI number: 153948841

Start: 1421842

End: 1423227

Strand: Reverse

Name: baeS [H]

Synonym: YpsIP31758_1211

Alternate gene names: 153948841

Gene position: 1423227-1421842 (Counterclockwise)

Preceding gene: 153947809

Following gene: 153949110

Centisome position: 30.13

GC content: 51.44

Gene sequence:

>1386_bases
ATGATAAGGATCGGCATTACCGGAAAACTGTTTATGGCTATTTTCGCCACTTGCATGTTGGTATTGATAACCATGCACTG
GGGCGTCAGGACCAGTTTTGAACGCGGTTTTATTGACTACATCAAGCAAAGTAATGAACAGCGGATCGCCATGCTAAGTC
ATGCGCTTGAAGGCGAATATCAGCACTACGGTAACTGGGATTTTCTGCGTAATAATGACCAAGTGATTTACCAGATCATG
CGATCCTTTGAGCAAAACCAAAACAGTGAGAACAGACCCAGTATGCCGCCCCGTGGCTGGCGCGCCCAATTTTGGGTGGT
TGATCAAGACAATAATCTGCTGGTCGGGCACTCCGGGCATCTCCCCACAGAAGCTAGCCGCAGTGCCATAAAAGTCAATG
ATCAGGTTGTCGGCTGGGTGATTTCGACCCCATCGGAAAAACTGACCCGTAATGCAGATATCACCTTTGATCAACAACAG
CGCCGCACCAGTTGGTTTATTGTTGGCCTCTCGACGCTGCTGGCGGCCGCCGTCACATGGGTACTCTCACGCGGCATGTT
AGCCCCAGTAAAACGGCTGGTTGAAGGCACGCATCGGCTGGCCGCGGGGGATTTTAGCACCCGTGTTGCCGTCAGTAGCC
GCGATGAACTGGGCCACCTAGCACAAGATTTTAACCAGCTAGCCAGTTCACTGGAAAAAAATGAACAAATGCGCCGTGAT
TTTATGGCCGATGTCTCCCATGAACTCCGCACGCCACTGGCAGTATTACGCGGAGAACTGGAAGCCTTACAAGACGGCCT
GCGCCAACCCACCCCCGAGTCATTAAGTTCGCTCCAAGCCGAGGTGGCGATTTTGACAAAACTGGTCAATGACCTGCACC
AGTTATCACAGTCTGATCGCGGGGCGCTGGCTTACCGTAAAACCCAACTGGATGTGGTCCGGCTACTGCAAGTGGCGATT
GCCAGCTTTCATGGCCGCTTCCAGAACAAAAAGATGACCATCACCGCCCACCTGCCTGAACACGCGGTTATTTTTGGCGA
CCCTGACCGGCTCAATCAGTTATTTCACAATTTACTGGAAAACAGCCTGCGTTATACCAACGAGGGGGGGACATTAGAAA
TTATCGCGTTGATCCAAGAAGAGACACTCACGCTGCACTGGCAAGACAGTAAACCGGGGGTCAGCGATGAACAGCTCGAG
CGTCTTTTTGAACGTTTTTATCGTACGGAAAGTTCACGTAATCGCGCCAGTGGCGGCTCTGGGTTGGGGTTGGCGATTTG
CCACAATATTGTCGATGCGCATGGCGGAAAAATCAGCGCTAAACATTCACCTTTGGGTGGCCTACGGATTACGGTAGTAT
TCCCCCTATTTCATTCCATAGGGTAA

Upstream 100 bases:

>100_bases
CGCCCTACCCGCCCTGATATTTAACCGCGTTCCCCCGGATACAGGAGCTAATCGTCATTTGGCCCGCTAGATTGGCCGAC
TGATAAAGACAGGTGAAATT

Downstream 100 bases:

>100_bases
TCCATTGTAATGCACGAGTCGCTTCTGTCTGCCAGCCAGTCTGGCTCTGTATTGATCGTTGAAGATGAACCCAAACTTGG
CCAGCTACTCGTCGATTACC

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEYQHYGNWDFLRNNDQVIYQIM
RSFEQNQNSENRPSMPPRGWRAQFWVVDQDNNLLVGHSGHLPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQ
RRTSWFIVGLSTLLAAAVTWVLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDRGALAYRKTQLDVVRLLQVAI
ASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLENSLRYTNEGGTLEIIALIQEETLTLHWQDSKPGVSDEQLE
RLFERFYRTESSRNRASGGSGLGLAICHNIVDAHGGKISAKHSPLGGLRITVVFPLFHSIG

Sequences:

>Translated_461_residues
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEYQHYGNWDFLRNNDQVIYQIM
RSFEQNQNSENRPSMPPRGWRAQFWVVDQDNNLLVGHSGHLPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQ
RRTSWFIVGLSTLLAAAVTWVLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDRGALAYRKTQLDVVRLLQVAI
ASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLENSLRYTNEGGTLEIIALIQEETLTLHWQDSKPGVSDEQLE
RLFERFYRTESSRNRASGGSGLGLAICHNIVDAHGGKISAKHSPLGGLRITVVFPLFHSIG
>Mature_461_residues
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEYQHYGNWDFLRNNDQVIYQIM
RSFEQNQNSENRPSMPPRGWRAQFWVVDQDNNLLVGHSGHLPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQ
RRTSWFIVGLSTLLAAAVTWVLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDRGALAYRKTQLDVVRLLQVAI
ASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLENSLRYTNEGGTLEIIALIQEETLTLHWQDSKPGVSDEQLE
RLFERFYRTESSRNRASGGSGLGLAICHNIVDAHGGKISAKHSPLGGLRITVVFPLFHSIG

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=456, Percent_Identity=65.5701754385965, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=29.7794117647059, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787894, Length=269, Percent_Identity=30.1115241635688, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=30.0353356890459, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786783, Length=289, Percent_Identity=27.3356401384083, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=30.6569343065693, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=28.4584980237154, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787374, Length=303, Percent_Identity=28.3828382838284, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789149, Length=381, Percent_Identity=25.1968503937008, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788713, Length=242, Percent_Identity=28.5123966942149, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790861, Length=307, Percent_Identity=27.0358306188925, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788279, Length=282, Percent_Identity=25.177304964539, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=25, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789403, Length=290, Percent_Identity=27.9310344827586, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=28.4403669724771, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790551, Length=278, Percent_Identity=28.4172661870504, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=276, Percent_Identity=26.8115942028986, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=25, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=25.2252252252252, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51968; Mature: 51968

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEY
CEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
QHYGNWDFLRNNDQVIYQIMRSFEQNQNSENRPSMPPRGWRAQFWVVDQDNNLLVGHSGH
HHCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCC
LPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQRRTSWFIVGLSTLLAAAVTW
CCCCCCCCEEEECCEEEEEEEECCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
VLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
HHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GALAYRKTQLDVVRLLQVAIASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHH
NSLRYTNEGGTLEIIALIQEETLTLHWQDSKPGVSDEQLERLFERFYRTESSRNRASGGS
HHHEECCCCCCEEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GLGLAICHNIVDAHGGKISAKHSPLGGLRITVVFPLFHSIG
CHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEHHHHHHHCC
>Mature Secondary Structure
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEY
CEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
QHYGNWDFLRNNDQVIYQIMRSFEQNQNSENRPSMPPRGWRAQFWVVDQDNNLLVGHSGH
HHCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCC
LPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQRRTSWFIVGLSTLLAAAVTW
CCCCCCCCEEEECCEEEEEEEECCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
VLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
HHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GALAYRKTQLDVVRLLQVAIASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHH
NSLRYTNEGGTLEIIALIQEETLTLHWQDSKPGVSDEQLERLFERFYRTESSRNRASGGS
HHHEECCCCCCEEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GLGLAICHNIVDAHGGKISAKHSPLGGLRITVVFPLFHSIG
CHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]