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The map label for this gene is yafV [C]

Identifier: 153948691

GI number: 153948691

Start: 467655

End: 468524

Strand: Direct

Name: yafV [C]

Synonym: YpsIP31758_0404

Alternate gene names: 153948691

Gene position: 467655-468524 (Clockwise)

Preceding gene: 153948116

Following gene: 153950166

Centisome position: 9.9

GC content: 49.43

Gene sequence:

>870_bases
ATGAAAAATGCCAATGTTGCATTATTGCAGTTGTGCAGCGGTGAAAATACCCGTGACAATCTGGCTCAAATTGAGCAGCA
GATCAAACAGTTAAATGCAGGTATCAAACTGGTTATGACGCCTGAAAATGCGTTGTTATTTGCTAATGCTGCCTCTTATC
GTCACCATGCGGAACAACATAATGACGGTCCATTACAGCAAGAAGTGCGTGAAATGGCACGGCGCTACGGGGTTTGGATA
CAGGTTGGTTCCATGCCTATGGTGAGCCGTGAGTCACCGGACCTGATCACCAGCAGTAGCTTGTTATTTGATGATCAAGG
CGAACTCAAAGCCCGTTACGATAAAATTCACATGTTTGATGTCGATATCAATGACATCCATGGCCATTACCGTGAGTCTG
ATACTTATCAGCCGGGGCAGCAGCTGACGGTGGTTGATACCCCGGTTGGCCGCTTGGGCATGACCATTTGCTATGACTTG
CGTTTCCCTGGCTTGTTTCAGGCTTTGCGAGCGCAGGGGGCTGAAATCATTTCTGTTCCGGCAGCCTTTACCAAAATGAC
GGGTGAGGCGCATTGGGAAACATTGCTCCGTGCACGGGCTATCGAAAACCAGTGCGTGATATTGGCTGCTGCACAGGTGG
GGCGTCACGGTGCTACCCGCCGGACGTGGGGCCATACCATGGCAGTCGATGCCTGGGGTAAAATTATTGGGCATAACCCA
GATGCGGTGGCGGCCCTAAAAGTAAGAATTGAAACCGCAGGTTTGAAGACGATTCGCAATCAAATGCCGGTCATGCAGCA
CAATCGCTTTCAGGCGACGCTGGAGCCGACATTGAATAAACCATTATTGAATAAACCACCATCTAATTAA

Upstream 100 bases:

>100_bases
TATGGAGCAAGGTTTCGCTGATCCGCTATCAGATTACCGGTAGTCTGGATCAACCGACCATCCATGAAGTGTTACGTCAG
CTAAAGGAGAATGAGGCGCC

Downstream 100 bases:

>100_bases
GAGTAAAAACTATGAGCCTCTCATTTGTCAGTGAGCAGTTACTCACTGCTAACAAGTTGAACCATGAGGACTTGTTCTCA
GTGTTGGGGCAGCTAACTGA

Product: hydrolase, carbon-nitrogen family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKNANVALLQLCSGENTRDNLAQIEQQIKQLNAGIKLVMTPENALLFANAASYRHHAEQHNDGPLQQEVREMARRYGVWI
QVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFDVDINDIHGHYRESDTYQPGQQLTVVDTPVGRLGMTICYDL
RFPGLFQALRAQGAEIISVPAAFTKMTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNP
DAVAALKVRIETAGLKTIRNQMPVMQHNRFQATLEPTLNKPLLNKPPSN

Sequences:

>Translated_289_residues
MKNANVALLQLCSGENTRDNLAQIEQQIKQLNAGIKLVMTPENALLFANAASYRHHAEQHNDGPLQQEVREMARRYGVWI
QVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFDVDINDIHGHYRESDTYQPGQQLTVVDTPVGRLGMTICYDL
RFPGLFQALRAQGAEIISVPAAFTKMTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNP
DAVAALKVRIETAGLKTIRNQMPVMQHNRFQATLEPTLNKPLLNKPPSN
>Mature_289_residues
MKNANVALLQLCSGENTRDNLAQIEQQIKQLNAGIKLVMTPENALLFANAASYRHHAEQHNDGPLQQEVREMARRYGVWI
QVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFDVDINDIHGHYRESDTYQPGQQLTVVDTPVGRLGMTICYDL
RFPGLFQALRAQGAEIISVPAAFTKMTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNP
DAVAALKVRIETAGLKTIRNQMPVMQHNRFQATLEPTLNKPLLNKPPSN

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI297632350, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI297632348, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=31.8518518518519, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI297632346, Length=192, Percent_Identity=32.8125, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=35.0746268656716, Blast_Score=177, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6322335, Length=300, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323383, Length=274, Percent_Identity=30.2919708029197, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17933642, Length=295, Percent_Identity=34.9152542372881, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355835, Length=274, Percent_Identity=27.7372262773723, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 32264; Mature: 32264

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNANVALLQLCSGENTRDNLAQIEQQIKQLNAGIKLVMTPENALLFANAASYRHHAEQH
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHCC
NDGPLQQEVREMARRYGVWIQVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFD
CCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCCEEECCCCCCEEEEEEEEEEE
VDINDIHGHYRESDTYQPGQQLTVVDTPVGRLGMTICYDLRFPGLFQALRAQGAEIISVP
CCHHHHCCCCCCCCCCCCCCEEEEEECCCCHHCCEEEEECCCCHHHHHHHHCCCEEEECC
AAFTKMTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNP
HHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCEEEHHHHHHHHCCCC
DAVAALKVRIETAGLKTIRNQMPVMQHNRFQATLEPTLNKPLLNKPPSN
CCEEEEEEEEEHHHHHHHHHCCCCHHCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNANVALLQLCSGENTRDNLAQIEQQIKQLNAGIKLVMTPENALLFANAASYRHHAEQH
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHCC
NDGPLQQEVREMARRYGVWIQVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFD
CCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCCEEECCCCCCEEEEEEEEEEE
VDINDIHGHYRESDTYQPGQQLTVVDTPVGRLGMTICYDLRFPGLFQALRAQGAEIISVP
CCHHHHCCCCCCCCCCCCCCEEEEEECCCCHHCCEEEEECCCCHHHHHHHHCCCEEEECC
AAFTKMTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNP
HHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCEEEHHHHHHHHCCCC
DAVAALKVRIETAGLKTIRNQMPVMQHNRFQATLEPTLNKPLLNKPPSN
CCEEEEEEEEEHHHHHHHHHCCCCHHCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]