Click here to switch to the map view.

The map label for this gene is yegH [H]

Identifier: 153948546

GI number: 153948546

Start: 2764110

End: 2765696

Strand: Direct

Name: yegH [H]

Synonym: YpsIP31758_2450

Alternate gene names: 153948546

Gene position: 2764110-2765696 (Clockwise)

Preceding gene: 153947642

Following gene: 153947488

Centisome position: 58.52

GC content: 46.94

Gene sequence:

>1587_bases
ATGGAATGGATCGCGGATCCAACTATTTGGGCAGGACTGGCTACATTGGTTGTGCTCGAAATTGTATTGGGTATTGATAA
CCTTATATTTATTGCCATCTTGGCAGAGAAACTTCCTCGTCATCAACGAGACAAAGCCAGAGTCACTGGTTTACTCTGCG
CATTGTTAATGCGTCTGGCACTGTTGGCCTGTATTTCGTGGCTGGCTACATTGACCACACCAATAGTCACTCTCTCTGAA
CATTCGTTCAGTGCACGTGACTTGATTATGTTGGTCGGGGGAATATTCCTGCTGTTCAAAGCTACGATGGAGCTAAATGA
ACGGCTGGAAGGGAAAGATCATCAGCAGAATCAGCAACGCAAAGCGGCTCGTTTCTGGCCGGTGGTGGCACAGATAGTGG
TTCTGGATGCTATCTTCTCGCTCGATTCCGTGATCACCGCCGTCGGCATGGTTGATCACCTTGCGGTGATGATGGCCGCC
GTTTGTATCGCAATTGGCTTGATGTTACTCGCCAGTAAACCGTTGACTCGCTTTGTCAATGCACATCCAACGATTGTCAT
TCTGTGCTTGAGCTTCTTACTGATGATCGGTTTCAGCTTAGTCGCTGAAGGTTTTGGTTACCATATTCCTAAGGGCTACC
TGTACGCGGCTATTGGTTTCTCAGTAATTATTGAGTCACTGAACCAGTTTGCACAATTCAATCGTCGGCGCTTCCTGTCA
ACGGTTAGACCATTACGCGAACGTACCGCAGAGGCCGTTTTACGGATGCTCAGTGGCAAACACGAAGAAGCTGAATTGGA
TAACCATACTGCCAATCTGATCGCTGATAATACCAGCGAAGGCCAGGAAGTGTTCAATGCGCAAGAACGGCGCATGATTG
AACGGGTCTTAGGGCTGGCACAGCGAACCGTCAGTAGCATCATGACATCACGCCATGATGTTGAATATTTGGACCTCAAT
GACCCACCAGAGAAATTGACTCAGTTGCTGGCGAAAAATCTGCATACCCGGATCGTGGTTACTGAAGATAGCTCTACTGA
TGAACCTTTGGGAGTTATTCACGTAATTGATTTATTGAAACAACAATTAGCGAATGAAAAACTCGACTTGCGGTCATTAA
TTCGCCAACCACTTATCTTTCCTGAGCAAGTTTCATTGCTGATGGCTCTGGAACAATTCCGTCAGGCACAGACACATTTT
GCTTTTGTCGTCGATGAGTTCGGTTCTATTGAGGGGGTTGTGACCCTTACCGACGTGATGGAAACTATCGCAGGTAATTT
ACCCGTAGCAGGGGAAGAGTTAGATGCGCGCCACGATATTCAGCAAACTGAAGATGGCTGTTGGATAGCGAACGGTTATA
TGCCGCTGGAAGATTTGGTGCTCTATTTGCCGCTGCCAATTGATGAAAAACGTGAATACCACACACTGGCCGGGTTACTC
ATGGAGCATACCCAGAGGATACCCAAAGTAGGTGAACAACTGACCATTGGCGATTACTTATTCGAACCTCTGGTGGTCAA
TAGCCACAGGATCTTAAAAGTGAAGATAACACCATTGAAGATTCCTGAGCCAGATTACGAAGTGTAG

Upstream 100 bases:

>100_bases
ATTTTTTTGTGATCGACTCTGGTCGATGCACTTTTTTAACAAATGGCTATTTTTCTGATTGACGGCATAAGCCGTAGCAA
TACAAGGTGAAACTGGATAT

Downstream 100 bases:

>100_bases
TTAATTGATAACGCTATAGATTAGGTGAATTAACAAAAGCCTGGAAAAATAAATGATTAGGCCCGGTGGAGAAACCATCG
GGCCTATCTCTTTCCACTAC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPRHQRDKARVTGLLCALLMRLALLACISWLATLTTPIVTLSE
HSFSARDLIMLVGGIFLLFKATMELNERLEGKDHQQNQQRKAARFWPVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVIIESLNQFAQFNRRRFLS
TVRPLRERTAEAVLRMLSGKHEEAELDNHTANLIADNTSEGQEVFNAQERRMIERVLGLAQRTVSSIMTSRHDVEYLDLN
DPPEKLTQLLAKNLHTRIVVTEDSSTDEPLGVIHVIDLLKQQLANEKLDLRSLIRQPLIFPEQVSLLMALEQFRQAQTHF
AFVVDEFGSIEGVVTLTDVMETIAGNLPVAGEELDARHDIQQTEDGCWIANGYMPLEDLVLYLPLPIDEKREYHTLAGLL
MEHTQRIPKVGEQLTIGDYLFEPLVVNSHRILKVKITPLKIPEPDYEV

Sequences:

>Translated_528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPRHQRDKARVTGLLCALLMRLALLACISWLATLTTPIVTLSE
HSFSARDLIMLVGGIFLLFKATMELNERLEGKDHQQNQQRKAARFWPVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVIIESLNQFAQFNRRRFLS
TVRPLRERTAEAVLRMLSGKHEEAELDNHTANLIADNTSEGQEVFNAQERRMIERVLGLAQRTVSSIMTSRHDVEYLDLN
DPPEKLTQLLAKNLHTRIVVTEDSSTDEPLGVIHVIDLLKQQLANEKLDLRSLIRQPLIFPEQVSLLMALEQFRQAQTHF
AFVVDEFGSIEGVVTLTDVMETIAGNLPVAGEELDARHDIQQTEDGCWIANGYMPLEDLVLYLPLPIDEKREYHTLAGLL
MEHTQRIPKVGEQLTIGDYLFEPLVVNSHRILKVKITPLKIPEPDYEV
>Mature_528_residues
MEWIADPTIWAGLATLVVLEIVLGIDNLIFIAILAEKLPRHQRDKARVTGLLCALLMRLALLACISWLATLTTPIVTLSE
HSFSARDLIMLVGGIFLLFKATMELNERLEGKDHQQNQQRKAARFWPVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
VCIAIGLMLLASKPLTRFVNAHPTIVILCLSFLLMIGFSLVAEGFGYHIPKGYLYAAIGFSVIIESLNQFAQFNRRRFLS
TVRPLRERTAEAVLRMLSGKHEEAELDNHTANLIADNTSEGQEVFNAQERRMIERVLGLAQRTVSSIMTSRHDVEYLDLN
DPPEKLTQLLAKNLHTRIVVTEDSSTDEPLGVIHVIDLLKQQLANEKLDLRSLIRQPLIFPEQVSLLMALEQFRQAQTHF
AFVVDEFGSIEGVVTLTDVMETIAGNLPVAGEELDARHDIQQTEDGCWIANGYMPLEDLVLYLPLPIDEKREYHTLAGLL
MEHTQRIPKVGEQLTIGDYLFEPLVVNSHRILKVKITPLKIPEPDYEV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=348, Percent_Identity=22.7011494252874, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082033, Length=529, Percent_Identity=72.2117202268431, Blast_Score=753, Evalue=0.0,
Organism=Escherichia coli, GI1788119, Length=517, Percent_Identity=49.7098646034816, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1789197, Length=226, Percent_Identity=51.3274336283186, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1790664, Length=239, Percent_Identity=33.0543933054393, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786879, Length=248, Percent_Identity=27.8225806451613, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693175, Length=251, Percent_Identity=26.6932270916335, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 59240; Mature: 59240

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCHHHHHHCCCEECCCEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCHHHHHHCCCEECCCEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]