Click here to switch to the map view.

The map label for this gene is arpC [H]

Identifier: 153948445

GI number: 153948445

Start: 631523

End: 632884

Strand: Reverse

Name: arpC [H]

Synonym: YpsIP31758_0533

Alternate gene names: 153948445

Gene position: 632884-631523 (Counterclockwise)

Preceding gene: 153949913

Following gene: 153950924

Centisome position: 13.4

GC content: 52.2

Gene sequence:

>1362_bases
ATGGGGGGCGGTAACTTTTCTGTGCCACCGAATCCGATCGTGGCCGAATTAGCCCAACCGCCGACCATAAAAAGTGATCA
TGCTTATTCATTGCCAGAATTGATTGATATCGCCCAACGTCAGAATCCGGATACCCGCATTGCCTGGCAGCAAGCGCGAC
AGGCAGCCCTTGCGGTAGGAATGGGGGAGGCGATATTTTTACCGATCATTTCTGCCAGTGTCATTGGTGGCTACCAGCGT
ACGACCACACCTCTGCCTTATGCTATCGGCAACGAAAAGGATCTGAAAACAACCGGGAGCGCGGTTGTTCCTGCTTTGGC
CTTACAGTGGCTTATCTTTGATTTCGGCCAGCGCAGCGCGTTGCTTGACGCCGCTAAACAGACGTCTTATGCCGCTAATG
TGACCTTCAATGGCATGCACCAGAAACTGATCTACGATGTGACACGCACTTACTTCCAATATGGTGCAGCACAAGCCCAG
AGCCAGATAGCAAAACAAACGTTGCAAAACAGTCTAAAGATTCAGGATGCTGCCGAGGAGCGCCAGAAAAAGGGTATTGC
GACAACGGTTGAAGTGGCGTTGGCACGCCAGCAAGTCGCACAGTCTCAGTTGCGTCGTGTGGTGGCAAAAGGTACTGAAC
GTGATGCTTATCAGGCATTATTAGGGGCGATGGGCGTTTCTCCATCATTGGATATCAAAGCCGCCTATACCGAAGATCGT
GCTTTACCAGATGGGATAAGCGCCCCGACAGAAAAGATGATCCAGTTGGCCCTCTCCCAGCGGCCAGATGTTTTAGCCAG
CTATGCGGCGGTCGAGGCAGCCAAGGCGGGTATCAAAGCCACTGAAGCCGATTTCTTGCCAAAAGTCTATCTGGCCGGGG
CTGTTGCTGGTGGTGATGGGCATTTTGATATTCAGGGCCTACCAGGTATCAGCCCGCAAACTTCATCCTCTAGCATTTTA
GTCGGTGTCAGTGTTCCTCTGTACGATGGCGGGATACGCGCAGCCAGAGTTAAAGAGGCAGAATCCCGCGCGGCTGTTGC
TGCTGAAGGATTTAAGAAAACGCAGGAATTGGCGGTGCGCGAAATTGTGGTAGCAGCAGATACATTGCGCTCTGCGCTCG
AATCCAATCAGGCGGCATTAAATCTCGTGAAGACCTCGTTTATCTCCTATGATGCGGCGCTGGAGTCTTATCGCAGTGGT
GTTGGCACCATAACGGTCGCCAATGAGGCGGCAAATGGTTTGTTGAATGCTCAACAAATGAGTACTGATGCACATGCCGC
CTCTTTGGTCGCCGCCGCCAATCTGGCTTTCGTCATGGGTAAAATGACCAACACCTCACCGCCTTTGGAGCTGCTTCATT
AA

Upstream 100 bases:

>100_bases
TTGGAGCCTGTTGATCGTAGGTTGTGCTACAGATCGCTTGGATCTTGCACCTGCATCTTACACCGAACCCTGGACGCCAG
ATGGGAATGCAAGGGCTTCC

Downstream 100 bases:

>100_bases
AGAGTGAATGGCCCCAATTCCATTAGGTATCCTCTTACCTCTCAAAATGGGGCCTCTCTATTTTCAAACAGTGTAAAGAT
TTTCAAACAGCGTAAAATCC

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGGGNFSVPPNPIVAELAQPPTIKSDHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAIFLPIISASVIGGYQR
TTTPLPYAIGNEKDLKTTGSAVVPALALQWLIFDFGQRSALLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQ
SQIAKQTLQNSLKIQDAAEERQKKGIATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDR
ALPDGISAPTEKMIQLALSQRPDVLASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQGLPGISPQTSSSSIL
VGVSVPLYDGGIRAARVKEAESRAAVAAEGFKKTQELAVREIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSG
VGTITVANEAANGLLNAQQMSTDAHAASLVAAANLAFVMGKMTNTSPPLELLH

Sequences:

>Translated_453_residues
MGGGNFSVPPNPIVAELAQPPTIKSDHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAIFLPIISASVIGGYQR
TTTPLPYAIGNEKDLKTTGSAVVPALALQWLIFDFGQRSALLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQ
SQIAKQTLQNSLKIQDAAEERQKKGIATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDR
ALPDGISAPTEKMIQLALSQRPDVLASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQGLPGISPQTSSSSIL
VGVSVPLYDGGIRAARVKEAESRAAVAAEGFKKTQELAVREIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSG
VGTITVANEAANGLLNAQQMSTDAHAASLVAAANLAFVMGKMTNTSPPLELLH
>Mature_452_residues
GGGNFSVPPNPIVAELAQPPTIKSDHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAIFLPIISASVIGGYQRT
TTPLPYAIGNEKDLKTTGSAVVPALALQWLIFDFGQRSALLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQS
QIAKQTLQNSLKIQDAAEERQKKGIATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDRA
LPDGISAPTEKMIQLALSQRPDVLASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQGLPGISPQTSSSSILV
GVSVPLYDGGIRAARVKEAESRAAVAAEGFKKTQELAVREIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSGV
GTITVANEAANGLLNAQQMSTDAHAASLVAAANLAFVMGKMTNTSPPLELLH

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=270, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47823; Mature: 47692

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGGNFSVPPNPIVAELAQPPTIKSDHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVG
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
MGEAIFLPIISASVIGGYQRTTTPLPYAIGNEKDLKTTGSAVVPALALQWLIFDFGQRSA
CCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
LLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQSQIAKQTLQNSLKIQDAAEE
HHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RQKKGIATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCC
ALPDGISAPTEKMIQLALSQRPDVLASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDG
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHEEEECCCC
HFDIQGLPGISPQTSSSSILVGVSVPLYDGGIRAARVKEAESRAAVAAEGFKKTQELAVR
CEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSGVGTITVANEAANGLLNAQQM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCHHHH
STDAHAASLVAAANLAFVMGKMTNTSPPLELLH
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure 
GGGNFSVPPNPIVAELAQPPTIKSDHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVG
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
MGEAIFLPIISASVIGGYQRTTTPLPYAIGNEKDLKTTGSAVVPALALQWLIFDFGQRSA
CCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
LLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQSQIAKQTLQNSLKIQDAAEE
HHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RQKKGIATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCC
ALPDGISAPTEKMIQLALSQRPDVLASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDG
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHEEEECCCC
HFDIQGLPGISPQTSSSSILVGVSVPLYDGGIRAARVKEAESRAAVAAEGFKKTQELAVR
CEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSGVGTITVANEAANGLLNAQQM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCHHHH
STDAHAASLVAAANLAFVMGKMTNTSPPLELLH
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]