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The map label for this gene is ydeN [H]

Identifier: 153948293

GI number: 153948293

Start: 1481692

End: 1483296

Strand: Direct

Name: ydeN [H]

Synonym: YpsIP31758_1263

Alternate gene names: 153948293

Gene position: 1481692-1483296 (Clockwise)

Preceding gene: 153947185

Following gene: 153947971

Centisome position: 31.37

GC content: 42.06

Gene sequence:

>1605_bases
ATGGGTGGCCCTGCATATGCTGATGATGTCAAACTCAAAGCAACAAACACCAATGTTGCTTTCGCTGATTTTACGCCAAA
AGAATACAGCACGAAGAATAAGCCAAATATCATTGTATTAACCATGGATGACTTAGGTTATGGGCAGCTCCCTTTTGATA
AGACCTCCTTTGACCCGAAGTCGATGGAAGATCGGGACGTTGTTGATACCTACAAAATAGGCATTGATAAAGCCATTGAA
GCCGCCAAAAAGTCCACGCCAACACTACTCTCGTTGATGGATGAAGGGGTTCGTCTGACGAATGGCTACGTTGCTCATGG
CGTATCAGGGCCTTCGCGGGCGGCCATTATGACGGGCCGGTCCCCTGCAAGGTTTGGTGTTTACTCCAATACCGATGCTC
AGAATGGGATTTCATTAGAAGAGACATTCCTGCCTGAGTTATTGCAAAACAATGGCTATTACACGGCGGCCATCGGAAAA
TGGCATCTTTCAAAAATCAGTAATGTTCCTGTTCCTGAAGCGGAGCAAACGCGCGATTACCACGATAACTTTACAACTTA
CTCAGCCGATGAATGGCAGCCTCAAAACCGAGGCTTCCAGTATTTTATGGGTTACCATGCCGCGGGAACGGCTTATTATA
ATTCCCCGTCTCTTTTCCATAATAAAGAGCGGGTGAAAGCCAAAGGTTATATCAGTGATCAACTTACCGATGAGGCTATC
GGTGTTGCCAATAGAGCTAAATCCTTAGATGAGCCATTCATGATGTATTTGGCTTACAGTGCTCCCCATTTACCTAATGA
TAATCCAGCGCCGGATGAATATCAGAAACACTTTAATACAGGTAGCCAAACTGCTGATAACTTCTATGCCTCTGTCTATT
CTGTTGACCAGGGCGTAAAACGGCTTCTTGAGCAGCTTAAAAAGAATGGTCAATATGACAATACGATAATTATGTTTACC
TCTGATAACGGTGCCGTTATCGATGGGCCATTACCGTTGAACGGTAATCAGAAAGGGTATAAAAGCCAAACATTTCCTGG
CGGAACCCATACTCCAATGTTTATTTGGTGGAAGGGGAAATTGCAAACAGGAAATTATGACAAGTTGATCTCTGCAATGG
ATTTCATGCCTACAGCGCTTGAAGCCGCTGAGATTGATGCTCCAAATAATTTAGATGGTGTCTCACTGCTTCCTTATTTG
ACGGGGAAAAGCAAAGCTGAACCGCATAAATATCTTACCTGGGTGACATCCTATACCCACTGGTTCGATGAAGAGAATAT
TCCATTCTGGGATGGTTACCATAAATTTGTGCGTAATGAATCCAATGAATATCCTAAAAACCCAAATACCGAAGATCTTA
GTCAATTCTCTTATACCATCCGCAGTAATGACTACTCTTTAACCTATACCTATGAAGGTAATAAGTTAAATTTGTATAAA
CTGAGTGATTTAAATCAAAAACAAGACCTTGCAAGTACCCATCCTGATGTTGTTAAGGTAATGCAAGCCGAGATGAGGAA
CTTCATTAATCAGAGTCAATCTCCTGTTAGTGAAGTTAATCAGGATAAATTTAATAAAATTAAGCAATCGCTTGGCATGA
ATTAA

Upstream 100 bases:

>100_bases
CAATTGGACGATAACCAGTAGAGAACTAAAAATGATGAATTTAAAGGTTAACAGGAGCATTATTAGTGCTTCGATATCGG
TCATCTTAGCTGCGGGCGTC

Downstream 100 bases:

>100_bases
GCCCCAAAGGCGGCAAGTATTTTTTCTTGCCGTCTGTCTATCTCCATGAGGAAAACTATGCATATCACGGCTAAACCAAC
CAGCTACCAGTGTAATTTAA

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSFDPKSMEDRDVVDTYKIGIDKAIE
AAKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGISLEETFLPELLQNNGYYTAAIGK
WHLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPSLFHNKERVKAKGYISDQLTDEAI
GVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQGVKRLLEQLKKNGQYDNTIIMFT
SDNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMPTALEAAEIDAPNNLDGVSLLPYL
TGKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFSYTIRSNDYSLTYTYEGNKLNLYK
LSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN

Sequences:

>Translated_534_residues
MGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSFDPKSMEDRDVVDTYKIGIDKAIE
AAKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGISLEETFLPELLQNNGYYTAAIGK
WHLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPSLFHNKERVKAKGYISDQLTDEAI
GVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQGVKRLLEQLKKNGQYDNTIIMFT
SDNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMPTALEAAEIDAPNNLDGVSLLPYL
TGKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFSYTIRSNDYSLTYTYEGNKLNLYK
LSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN
>Mature_533_residues
GGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSFDPKSMEDRDVVDTYKIGIDKAIEA
AKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGRSPARFGVYSNTDAQNGISLEETFLPELLQNNGYYTAAIGKW
HLSKISNVPVPEAEQTRDYHDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPSLFHNKERVKAKGYISDQLTDEAIG
VANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQGVKRLLEQLKKNGQYDNTIIMFTS
DNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGKLQTGNYDKLISAMDFMPTALEAAEIDAPNNLDGVSLLPYLT
GKSKAEPHKYLTWVTSYTHWFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFSYTIRSNDYSLTYTYEGNKLNLYKL
SDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=387, Percent_Identity=28.9405684754522, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI146229331, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI146229329, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI6005990, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI146229324, Length=419, Percent_Identity=26.2529832935561, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI45430057, Length=440, Percent_Identity=25.9090909090909, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI59797060, Length=483, Percent_Identity=26.0869565217391, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI109389362, Length=341, Percent_Identity=26.9794721407625, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38569405, Length=376, Percent_Identity=25.531914893617, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38569407, Length=376, Percent_Identity=25.531914893617, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4504061, Length=377, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI58743319, Length=184, Percent_Identity=32.6086956521739, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI53831991, Length=185, Percent_Identity=30.2702702702703, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87081924, Length=526, Percent_Identity=82.319391634981, Blast_Score=918, Evalue=0.0,
Organism=Escherichia coli, GI1790233, Length=397, Percent_Identity=26.9521410579345, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI115533416, Length=535, Percent_Identity=24.1121495327103, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI115533418, Length=483, Percent_Identity=25.2587991718427, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24666109, Length=410, Percent_Identity=29.0243902439024, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281366397, Length=395, Percent_Identity=29.3670886075949, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281366395, Length=395, Percent_Identity=29.3670886075949, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24666163, Length=395, Percent_Identity=29.3670886075949, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24666175, Length=412, Percent_Identity=26.2135922330097, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363223, Length=374, Percent_Identity=25.9358288770053, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24647401, Length=363, Percent_Identity=23.4159779614325, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653364, Length=352, Percent_Identity=24.7159090909091, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19922168, Length=352, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 60116; Mature: 59985

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSFDPK
CCCCCCCCCEEEEEECCEEEEEECCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
SMEDRDVVDTYKIGIDKAIEAAKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGR
CCCCCCCHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCEEECCEEEECCCCCCCEEEEECC
SPARFGVYSNTDAQNGISLEETFLPELLQNNGYYTAAIGKWHLSKISNVPVPEAEQTRDY
CCCEECEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
HDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPSLFHNKERVKAKGYISDQLTDEAI
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCHHHCCHHHHEECCCCCHHHHHHHH
GVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQGVK
HHHHHHHCCCCHHEEHEECCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RLLEQLKKNGQYDNTIIMFTSDNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGK
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECE
LQTGNYDKLISAMDFMPTALEAAEIDAPNNLDGVSLLPYLTGKSKAEPHKYLTWVTSYTH
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHEEHHHHHHH
WFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFSYTIRSNDYSLTYTYEGNKLNLYK
HCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHEEEEECCCEEEEEEEECCEEEEEE
LSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN
ECCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GGPAYADDVKLKATNTNVAFADFTPKEYSTKNKPNIIVLTMDDLGYGQLPFDKTSFDPK
CCCCCCCCEEEEEECCEEEEEECCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
SMEDRDVVDTYKIGIDKAIEAAKKSTPTLLSLMDEGVRLTNGYVAHGVSGPSRAAIMTGR
CCCCCCCHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCEEECCEEEECCCCCCCEEEEECC
SPARFGVYSNTDAQNGISLEETFLPELLQNNGYYTAAIGKWHLSKISNVPVPEAEQTRDY
CCCEECEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
HDNFTTYSADEWQPQNRGFQYFMGYHAAGTAYYNSPSLFHNKERVKAKGYISDQLTDEAI
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCHHHCCHHHHEECCCCCHHHHHHHH
GVANRAKSLDEPFMMYLAYSAPHLPNDNPAPDEYQKHFNTGSQTADNFYASVYSVDQGVK
HHHHHHHCCCCHHEEHEECCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RLLEQLKKNGQYDNTIIMFTSDNGAVIDGPLPLNGNQKGYKSQTFPGGTHTPMFIWWKGK
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECE
LQTGNYDKLISAMDFMPTALEAAEIDAPNNLDGVSLLPYLTGKSKAEPHKYLTWVTSYTH
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHEEHHHHHHH
WFDEENIPFWDGYHKFVRNESNEYPKNPNTEDLSQFSYTIRSNDYSLTYTYEGNKLNLYK
HCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHEEEEECCCEEEEEEEECCEEEEEE
LSDLNQKQDLASTHPDVVKVMQAEMRNFINQSQSPVSEVNQDKFNKIKQSLGMN
ECCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]