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The map label for this gene is alr [H]

Identifier: 153948196

GI number: 153948196

Start: 4241708

End: 4242787

Strand: Reverse

Name: alr [H]

Synonym: YpsIP31758_3764

Alternate gene names: 153948196

Gene position: 4242787-4241708 (Counterclockwise)

Preceding gene: 153948576

Following gene: 153948630

Centisome position: 89.83

GC content: 54.81

Gene sequence:

>1080_bases
ATGAAAGCGGCAACAGCAGTCATCGACCGCCATGCTCTGCGACATAACTTACAACAAATTCGGCGTCTGGCACCGCAAAG
CCGGTTGGTGGCTGTTGTGAAAGCAAATGCTTATGGCCACGGGTTATTAGCCGCAGCACACACATTACAGGATGCTGATT
GTTATGGCGTGGCCCGTATTAGCGAGGCGCTGATGTTGCGAGCGGGTGGAATAGTTAAACCTATTTTGCTGCTGGAAGGG
TTCTTTGATGCAGAAGACCTGCCGGTATTGGTGGCTAACCACATTGAAACCGCCGTTCACAGCCTGGAACAGCTCGTGGC
ATTGGAAGCGGCTAGGCTTTCTGCGCCGATTAATGCCTGGATGAAATTGGATACGGGGATGCACCGCCTGGGGGTTCGCC
CAGATCAGGCCGAAGCGTTTTATCAGCGTTTGAGCGCATGCCGTAACGTCATCCAGCCGGTCAATATCATGAGTCACTTT
AGCCGTGCCGATGAACCTGAAGTGGCGGCCACGCAACAGCAACTGGCGTGTTTTGATGCGTTTGCTGCAGGTAAACCTGG
GAAACAATCTATCGCTGCTTCGGGCGGTATTCTGCGGTGGCCACAAGCGCACCGTGATTGGGTGCGCCCAGGGATTGTGC
TGTATGGGGTTTCGCCGTTTGATGCGCCCTATGGCCGTGATTTCGGTTTATTGCCCGCCATGACCCTGAAATCCAGTCTG
ATCGCGGTGCGTGAACATAAAGCCGGTGAATCGGTCGGGTATGGCGGCACCTGGGTCAGTGAGCGCGATACGCGTTTAGG
TGTGATCGCGATAGGCTATGGTGATGGCTACCCACGTAGCGCCCCGTCAGGGACACCGGTATGGCTTAATGGCCGTGAAG
TGAGCATCGTTGGCCGGGTATCGATGGACATGATCTCCATTGATCTTGGCCCGGAAAGTACAGATAAGGTGGGCGATGAA
GCCCTGATGTGGGGAGCCGAATTACCGGTTGAACGCGTGGCTGCCTGCACCGGTATCAGCGCGTATGAATTGATCACTAA
TCTGACCTCCCGCGTAGCGATGGAATATCTAGGGGAATAA

Upstream 100 bases:

>100_bases
GTAGTGAATAGCCTCTTGGTATTTGATACTGCCGAGGTGAGCACGGACTACCTGCAACGCCAATCATGTTGGGAATAATA
TCAATTATTAAGGATAAGAA

Downstream 100 bases:

>100_bases
GGTAAGCTGCAAGAGCGACCCATTTCCATATACCCGCCATATTTCAAATTGCAGGCGTGCTGGTTGTCTGCGTCCCCCTT
GGTCACTTACTCATGTAAGC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKAATAVIDRHALRHNLQQIRRLAPQSRLVAVVKANAYGHGLLAAAHTLQDADCYGVARISEALMLRAGGIVKPILLLEG
FFDAEDLPVLVANHIETAVHSLEQLVALEAARLSAPINAWMKLDTGMHRLGVRPDQAEAFYQRLSACRNVIQPVNIMSHF
SRADEPEVAATQQQLACFDAFAAGKPGKQSIAASGGILRWPQAHRDWVRPGIVLYGVSPFDAPYGRDFGLLPAMTLKSSL
IAVREHKAGESVGYGGTWVSERDTRLGVIAIGYGDGYPRSAPSGTPVWLNGREVSIVGRVSMDMISIDLGPESTDKVGDE
ALMWGAELPVERVAACTGISAYELITNLTSRVAMEYLGE

Sequences:

>Translated_359_residues
MKAATAVIDRHALRHNLQQIRRLAPQSRLVAVVKANAYGHGLLAAAHTLQDADCYGVARISEALMLRAGGIVKPILLLEG
FFDAEDLPVLVANHIETAVHSLEQLVALEAARLSAPINAWMKLDTGMHRLGVRPDQAEAFYQRLSACRNVIQPVNIMSHF
SRADEPEVAATQQQLACFDAFAAGKPGKQSIAASGGILRWPQAHRDWVRPGIVLYGVSPFDAPYGRDFGLLPAMTLKSSL
IAVREHKAGESVGYGGTWVSERDTRLGVIAIGYGDGYPRSAPSGTPVWLNGREVSIVGRVSMDMISIDLGPESTDKVGDE
ALMWGAELPVERVAACTGISAYELITNLTSRVAMEYLGE
>Mature_359_residues
MKAATAVIDRHALRHNLQQIRRLAPQSRLVAVVKANAYGHGLLAAAHTLQDADCYGVARISEALMLRAGGIVKPILLLEG
FFDAEDLPVLVANHIETAVHSLEQLVALEAARLSAPINAWMKLDTGMHRLGVRPDQAEAFYQRLSACRNVIQPVNIMSHF
SRADEPEVAATQQQLACFDAFAAGKPGKQSIAASGGILRWPQAHRDWVRPGIVLYGVSPFDAPYGRDFGLLPAMTLKSSL
IAVREHKAGESVGYGGTWVSERDTRLGVIAIGYGDGYPRSAPSGTPVWLNGREVSIVGRVSMDMISIDLGPESTDKVGDE
ALMWGAELPVERVAACTGISAYELITNLTSRVAMEYLGE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=358, Percent_Identity=71.7877094972067, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI1787439, Length=350, Percent_Identity=42.8571428571429, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38759; Mature: 38759

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAATAVIDRHALRHNLQQIRRLAPQSRLVAVVKANAYGHGLLAAAHTLQDADCYGVARI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHH
SEALMLRAGGIVKPILLLEGFFDAEDLPVLVANHIETAVHSLEQLVALEAARLSAPINAW
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MKLDTGMHRLGVRPDQAEAFYQRLSACRNVIQPVNIMSHFSRADEPEVAATQQQLACFDA
HHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FAAGKPGKQSIAASGGILRWPQAHRDWVRPGIVLYGVSPFDAPYGRDFGLLPAMTLKSSL
HHCCCCCCHHHHCCCCEEECCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IAVREHKAGESVGYGGTWVSERDTRLGVIAIGYGDGYPRSAPSGTPVWLNGREVSIVGRV
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEEE
SMDMISIDLGPESTDKVGDEALMWGAELPVERVAACTGISAYELITNLTSRVAMEYLGE
EEEEEEEECCCCCCHHCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAATAVIDRHALRHNLQQIRRLAPQSRLVAVVKANAYGHGLLAAAHTLQDADCYGVARI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHH
SEALMLRAGGIVKPILLLEGFFDAEDLPVLVANHIETAVHSLEQLVALEAARLSAPINAW
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MKLDTGMHRLGVRPDQAEAFYQRLSACRNVIQPVNIMSHFSRADEPEVAATQQQLACFDA
HHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FAAGKPGKQSIAASGGILRWPQAHRDWVRPGIVLYGVSPFDAPYGRDFGLLPAMTLKSSL
HHCCCCCCHHHHCCCCEEECCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IAVREHKAGESVGYGGTWVSERDTRLGVIAIGYGDGYPRSAPSGTPVWLNGREVSIVGRV
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEEE
SMDMISIDLGPESTDKVGDEALMWGAELPVERVAACTGISAYELITNLTSRVAMEYLGE
EEEEEEEECCCCCCHHCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]