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The map label for this gene is dicA [C]

Identifier: 153948175

GI number: 153948175

Start: 2554676

End: 2555386

Strand: Direct

Name: dicA [C]

Synonym: YpsIP31758_2248

Alternate gene names: 153948175

Gene position: 2554676-2555386 (Clockwise)

Preceding gene: 153946959

Following gene: 153948662

Centisome position: 54.09

GC content: 40.51

Gene sequence:

>711_bases
ATGGTAAAGCAAACACTTTTCACATCGTTATCAAGTAACATTAGTTACATGAAAACTGAAATGAATGACCGTATCCGTCT
TCGCAGACTGCAGTTGGATCTCACTCAACTCCAATTGGCCAAAGCTATTGGGGTGAGTAGAGTGTCAGTTACAAAATGGG
AGTCAGGAATAACTAAACCTGATGGAGAAAACCTCCATCGGCTTGCACAAACCCTTTCATGTACTCCTGAATGGATTCTC
TACGGAACAGGGGATTTACGTCAGGCTGATGATACAAATCTCATGCCTGCCACAGTAGTGCCTACAGCTATACCTATTAT
TTCATCAGTTCAAGCTGGAGTATGGACTGACACATTTTCCGCAGTCGGTATTTCTGATGTGCTGAGATGGTGTAGCACCA
CCGTAAAAGTTTCTGATAGCGCATTTGCATTAGATGTTCGTGGGGAATCAATGACAAACCCCAATGGTTTACCCTCTATA
CCCGAAGGTTCGACTGTTATTGTTGAACCTAATTATGGTTCTATCGAAGACTTATACGGCAAGATAGTAGTCGTTATCAT
TGATGGTAGTTCCGAAACTACAATTAAAAAATTAGTTGTAGACGGCCCCAATAAATATTTGATGCCACTAAATCCGAACT
TTAAACCAATTGAAATCAAAGGTAACTACCGTATTCTCGGTAAGGTAGTTCAAGTTACTCAAGACTTATAA

Upstream 100 bases:

>100_bases
AGCTATAGCAGTATTAACAACCCCACCAAAAAACTTAACGACATCTTTTTTTTTCATAAAGCACTCCTCTTTAACCCCAA
TCAAAGGTAACAAAAGGTAC

Downstream 100 bases:

>100_bases
TCAATAACCCATCATTGATGGTATGGGCTATTCCACGCCCCGACATGTAACCAGAGGTACGGTCATATTGACAAAATTGG
TACTTTTAGGTACACTCATA

Product: repressor protein C2

Products: NA

Alternate protein names: ORF-96 protein [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MVKQTLFTSLSSNISYMKTEMNDRIRLRRLQLDLTQLQLAKAIGVSRVSVTKWESGITKPDGENLHRLAQTLSCTPEWIL
YGTGDLRQADDTNLMPATVVPTAIPIISSVQAGVWTDTFSAVGISDVLRWCSTTVKVSDSAFALDVRGESMTNPNGLPSI
PEGSTVIVEPNYGSIEDLYGKIVVVIIDGSSETTIKKLVVDGPNKYLMPLNPNFKPIEIKGNYRILGKVVQVTQDL

Sequences:

>Translated_236_residues
MVKQTLFTSLSSNISYMKTEMNDRIRLRRLQLDLTQLQLAKAIGVSRVSVTKWESGITKPDGENLHRLAQTLSCTPEWIL
YGTGDLRQADDTNLMPATVVPTAIPIISSVQAGVWTDTFSAVGISDVLRWCSTTVKVSDSAFALDVRGESMTNPNGLPSI
PEGSTVIVEPNYGSIEDLYGKIVVVIIDGSSETTIKKLVVDGPNKYLMPLNPNFKPIEIKGNYRILGKVVQVTQDL
>Mature_236_residues
MVKQTLFTSLSSNISYMKTEMNDRIRLRRLQLDLTQLQLAKAIGVSRVSVTKWESGITKPDGENLHRLAQTLSCTPEWIL
YGTGDLRQADDTNLMPATVVPTAIPIISSVQAGVWTDTFSAVGISDVLRWCSTTVKVSDSAFALDVRGESMTNPNGLPSI
PEGSTVIVEPNYGSIEDLYGKIVVVIIDGSSETTIKKLVVDGPNKYLMPLNPNFKPIEIKGNYRILGKVVQVTQDL

Specific function: May control the expression of the integrase and inhibit excision of the mobile element R391, and regulate the expression of other genes as well [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787853, Length=63, Percent_Identity=50.7936507936508, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787391, Length=132, Percent_Identity=32.5757575757576, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF01381 HTH_3; PF00717 Peptidase_S24 [H]

EC number: NA

Molecular weight: Translated: 25871; Mature: 25871

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKQTLFTSLSSNISYMKTEMNDRIRLRRLQLDLTQLQLAKAIGVSRVSVTKWESGITKP
CCCHHHHHHHHCCHHEEHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCC
DGENLHRLAQTLSCTPEWILYGTGDLRQADDTNLMPATVVPTAIPIISSVQAGVWTDTFS
CCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
AVGISDVLRWCSTTVKVSDSAFALDVRGESMTNPNGLPSIPEGSTVIVEPNYGSIEDLYG
HCCHHHHHHHHCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHHCCC
KIVVVIIDGSSETTIKKLVVDGPNKYLMPLNPNFKPIEIKGNYRILGKVVQVTQDL
EEEEEEECCCCCCEEEEEEEECCCCEEEECCCCCCEEEEECCCEEHHHHHHHHHCC
>Mature Secondary Structure
MVKQTLFTSLSSNISYMKTEMNDRIRLRRLQLDLTQLQLAKAIGVSRVSVTKWESGITKP
CCCHHHHHHHHCCHHEEHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCC
DGENLHRLAQTLSCTPEWILYGTGDLRQADDTNLMPATVVPTAIPIISSVQAGVWTDTFS
CCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
AVGISDVLRWCSTTVKVSDSAFALDVRGESMTNPNGLPSIPEGSTVIVEPNYGSIEDLYG
HCCHHHHHHHHCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHHCCC
KIVVVIIDGSSETTIKKLVVDGPNKYLMPLNPNFKPIEIKGNYRILGKVVQVTQDL
EEEEEEECCCCCCEEEEEEEECCCCEEEECCCCCCEEEEECCCEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157923; 12193633 [H]