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The map label for this gene is nagZ

Identifier: 153948161

GI number: 153948161

Start: 1848362

End: 1849393

Strand: Direct

Name: nagZ

Synonym: YpsIP31758_1592

Alternate gene names: 153948161

Gene position: 1848362-1849393 (Clockwise)

Preceding gene: 153948734

Following gene: 153947824

Centisome position: 39.13

GC content: 52.13

Gene sequence:

>1032_bases
GTGGGTCCCGTGATGTTAGATGTTGCCAGCTATGAGCTGGATGCTGAAGAGCGTGAGATTTTAAAACACCCACTGGTGGG
AGGGTTGATCTTATTCAGCCGTAATTTTCATGATGCGGAGCAGTTACGCGAATTAGTACGCCAAATCCGTGCAGCATCGC
ATGAACGTTTGGTGGTCGCAGTGGATCAGGAAGGGGGGCGGGTCCAACGCTTTCGTGACGGTTTTACCCGCCTGCCAGCG
GCTCAGTCTTTCGCGGCTATCAATGATGCCGCTACTGCGGCTCAACTGGCGCAAGAGGCGGGGTGGTTGATGGCAGCAGA
AATGATGGCGATGGATATTGATATCAGTTTTGCTCCAGTACTGGATATTGGCCATGTCAGCGCCGCAATTGGTGAGCGTT
CATTCCACAGTGATCCACAACAGGCGCGGATAATGGCGGAGTGTTTCATCCGTGGGATGCACAGTGCAGGGATGAAAACC
ACGGGCAAGCATTTTCCAGGGCACGGCGCAGTAACCGCAGATTCACATAAAGAGACGCCACATGATAATCGGCCACTGGC
AGAAATCCGTACTCATGATATGGTTATATTTCGTGAATTGATCCAGCGGAAATTACTGGATGCGATTATGCCTGCTCACG
TGATTTATACCGAAGCCGATGCACGGCCTGCCAGCGGTTCTGCCTATTGGTTACAAGAGATATTGCGCCAAGAGCTAGGG
TTCGAGGGCATCATTTTCTCTGATGATCTCTCGATGGAAGGGGCTGCGATCATGGGCAGTTACGCCGAGCGCGGCCAGGC
ATCGTTGGATGCCGGTTGCGATATGATTTTGGTGTGTAATAACCGTCAGGGGGCCGTGAGTGTGCTGGATAATCTGTCTC
CGATCAAAGCCGACCAACTGACCCGTTTGTACCATTCAGGGCAATTTGACCGCCAGACATTGATGGCTTCATCCCGTTGG
CAACAGGCGAATAAAGCATTAACGGCACTCAGCGAACGTTGGGATGCACATAAACAAACGTTGGGGCAATAG

Upstream 100 bases:

>100_bases
TTGCGCCAACGTTTTAATTTGTCTTTTTAAGCCCTGCGGCACCAAGCCCGCCGCTTCAAGCACGAAGGGTCGTTATCAAT
CTGAATAAAGTGAGGTGACC

Downstream 100 bases:

>100_bases
GAGTAGTGCCGGGTACGCTTCGGTATTATTACTCGCCTCATAAGGGCCAAGAGCTCCCTCTTTTCTGTGGGGGCTTTGAT
CAGTAACGCACACTGCCGCG

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRLPA
AQSFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKT
TGKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELG
FEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASSRW
QQANKALTALSERWDAHKQTLGQ

Sequences:

>Translated_343_residues
MGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRLPA
AQSFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKT
TGKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELG
FEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASSRW
QQANKALTALSERWDAHKQTLGQ
>Mature_342_residues
GPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRLPAA
QSFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTT
GKHFPGHGAVTADSHKETPHDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELGF
EGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASSRWQ
QANKALTALSERWDAHKQTLGQ

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=338, Percent_Identity=76.9230769230769, Blast_Score=545, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_YERP3 (A7FH41)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400569.1
- ProteinModelPortal:   A7FH41
- SMR:   A7FH41
- STRING:   A7FH41
- GeneID:   5385802
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1592
- NMPDR:   fig|349747.3.peg.941
- eggNOG:   COG1472
- HOGENOM:   HBG617255
- OMA:   VERSIRM
- ProtClustDB:   PRK05337
- BioCyc:   YPSE349747:YPSIP31758_1592-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 37904; Mature: 37772

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 248-248

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVA
CCCEEEEEHHCCCCHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
VDQEGGRVQRFRDGFTRLPAAQSFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPV
ECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCH
LDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTTGKHFPGHGAVTADSHKETP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
HDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCHHHHHHHHHHHCC
FEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQL
CCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHH
TRLYHSGQFDRQTLMASSRWQQANKALTALSERWDAHKQTLGQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVA
CCEEEEEHHCCCCHHHHHHHHCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
VDQEGGRVQRFRDGFTRLPAAQSFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPV
ECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCH
LDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTTGKHFPGHGAVTADSHKETP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
HDNRPLAEIRTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCHHHHHHHHHHHCC
FEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQL
CCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHH
TRLYHSGQFDRQTLMASSRWQQANKALTALSERWDAHKQTLGQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA