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The map label for this gene is arsR [H]

Identifier: 153947972

GI number: 153947972

Start: 3692886

End: 3693227

Strand: Direct

Name: arsR [H]

Synonym: YpsIP31758_3281

Alternate gene names: 153947972

Gene position: 3692886-3693227 (Clockwise)

Preceding gene: 153948462

Following gene: 153949826

Centisome position: 78.18

GC content: 48.54

Gene sequence:

>342_bases
ATGACAACACTCACGCCGTTGCAACTTTTTAAGAACTTATCGGATGAAACACGTCTGAATATTATCTTATTGCTAAAAGC
ATCCGGCGAACTGTGTGTTTGTGAGCTTTGCCATCGCTTAAATGAAGCCCAACCCAAGATTTCCAGGCATTTAGCCATGC
TAAGAGAGTCCGGGCTGTTACTGGATCGCCGGGCAGGGAAATGGGTCCACTACCGCCTGTCGCCCCATATTCCAGCTTGG
GCCGCAGCCATCATCGAGCAAACTTATCTCAGCCAACGCGATGAAATAACGTTACTGGCGCAGGGTAACGTCACTCCCGA
CAGCAAAATGTTGTGTAACTAA

Upstream 100 bases:

>100_bases
CCCTCCCCGCGCCCAATACACATTTGAAAAAACAAATATGAAATTGACATTCTCTCGTTGAACACTAAGATAGCGGAGAA
AAATTCATTCAGGGAGCATC

Downstream 100 bases:

>100_bases
CCTATTTAAAATTTACCTAATTATATCTGTTTCTCCATATATGACCGGATGGAACGACACACTATTTAACTCAGCGGAGG
CGTTATGTTGTTGGCTGGTG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MTTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRESGLLLDRRAGKWVHYRLSPHIPAW
AAAIIEQTYLSQRDEITLLAQGNVTPDSKMLCN

Sequences:

>Translated_113_residues
MTTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRESGLLLDRRAGKWVHYRLSPHIPAW
AAAIIEQTYLSQRDEITLLAQGNVTPDSKMLCN
>Mature_112_residues
TTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRESGLLLDRRAGKWVHYRLSPHIPAWA
AAIIEQTYLSQRDEITLLAQGNVTPDSKMLCN

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=117, Percent_Identity=60.6837606837607, Blast_Score=148, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12821; Mature: 12690

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRESGLL
CCCCCHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
LDRRAGKWVHYRLSPHIPAWAAAIIEQTYLSQRDEITLLAQGNVTPDSKMLCN
EECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRESGLL
CCCCHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
LDRRAGKWVHYRLSPHIPAWAAAIIEQTYLSQRDEITLLAQGNVTPDSKMLCN
EECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]