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The map label for this gene is yeaD [H]

Identifier: 153947966

GI number: 153947966

Start: 2289346

End: 2290221

Strand: Direct

Name: yeaD [H]

Synonym: YpsIP31758_1989

Alternate gene names: 153947966

Gene position: 2289346-2290221 (Clockwise)

Preceding gene: 153947807

Following gene: 153950478

Centisome position: 48.47

GC content: 48.17

Gene sequence:

>876_bases
ATGAACGAGAAAGTATTTACTCTCCCTGTTGTTGAACAAATCTCTCCTTATATCAGCCAGCGTCAACTGGATGAATTACC
GGTAGTGGTTGTTTCTCATCCTAAGGTGCGTGCGGCAATAAGTTTGCAGGGGGCCCACTTACTGGCCTATCAACCCAGTG
GTGAGCAACCTATTATTTGGCTGAGCAATAACACGCCGTTTAAAGAGGGTATTGCGATTCGTGGAGGGGTTCCAATTTGT
TGGCCTTGGTTTGGCCCAACCGCACAACCTGCCCATGGTTTTGCCCGCATCTTACCATGGACACTCAGTGCTCATGATGA
AAATGAAAACGGCGTCATTCTGACTTTTACCCTTGAAGACAGCGACATGACCCGCCAATACTGGCCACATGCCTTCACCC
TGATCGCCCGTTTCAAGTTGGGAGATGAATGTGAAGTTGAACTGGAATCACACGGTGATTATCAGGCTGCTGCGGCATTA
CATACCTACTTCCAGATTGGCGATATAAGCCACATTAAAGTCAGCGGGCTGGGTGAGAAATATTTAGATAAAGTGCTGAA
AGTTGCCGATGTCACTCAACAAGGCGATTTAGTCTTTAACGGCCAAACTGACCGTGTCTATACCCAACCTGAAGCCTATA
GTCTGATAAAAGATGCCGCGCTGAAACGAACTATTGAGGTCCATCACCATCACCAAAGTGATGTGGTTGCCTGGAACCCC
GGCGCTGAATTGTCCTGCAGCATGGTAGATATGCCAAATGATGGCTATAAAACGATGGTTTGCGTAGAAACCGCACGAGT
CAACAAGCCATTGGTGGCTGCGCCTGATGCACCAGCACGTTTGGCGATGACCATCCGTAGCCGTAAAAACACCTAA

Upstream 100 bases:

>100_bases
CACCTGCATCGCACGCTTGCTGCAAGATTCAATGCCTGTGATATTATCGAAAGACTGAAGCTCAACTGAATCCAGTTCCT
TTACCCATAAGGCCAAACGA

Downstream 100 bases:

>100_bases
TCCCGGCAGTCCGGTCAATATAAAAATGGGGCCTTTGGCCCCATGGTCTTGCTCATAGCAACTCAACGCTGATTAGCGGA
ATGTATAGGTAACGCCTGTC

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIWLSNNTPFKEGIAIRGGVPIC
WPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLEDSDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAAL
HTYFQIGDISHIKVSGLGEKYLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT

Sequences:

>Translated_291_residues
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIWLSNNTPFKEGIAIRGGVPIC
WPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLEDSDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAAL
HTYFQIGDISHIKVSGLGEKYLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT
>Mature_291_residues
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIWLSNNTPFKEGIAIRGGVPIC
WPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLEDSDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAAL
HTYFQIGDISHIKVSGLGEKYLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=293, Percent_Identity=55.9726962457338, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6323746, Length=272, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI19921284, Length=253, Percent_Identity=32.4110671936759, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28574481, Length=168, Percent_Identity=30.952380952381, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 32378; Mature: 32378

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIW
CCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEEECCCCCCCEEE
LSNNTPFKEGIAIRGGVPICWPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLED
EECCCCHHHCEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCCEEEEEEECC
SDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAALHTYFQIGDISHIKVSGLGEK
CCCCHHHCCHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHEECCCCEEEEECCCHH
YLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
HHHHHHHHHCCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHEEEECCCCCEEEECC
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT
CCCEEEEEEECCCCCCEEEEEEEEHHCCCCEEECCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIW
CCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEEECCCCCCCEEE
LSNNTPFKEGIAIRGGVPICWPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLED
EECCCCHHHCEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCCEEEEEEECC
SDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAALHTYFQIGDISHIKVSGLGEK
CCCCHHHCCHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHEECCCCEEEEECCCHH
YLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
HHHHHHHHHCCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHEEEECCCCCEEEECC
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT
CCCEEEEEEECCCCCCEEEEEEEEHHCCCCEEECCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]