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The map label for this gene is secM

Identifier: 153947714

GI number: 153947714

Start: 3799506

End: 3800039

Strand: Reverse

Name: secM

Synonym: YpsIP31758_3379

Alternate gene names: 153947714

Gene position: 3800039-3799506 (Counterclockwise)

Preceding gene: 153950483

Following gene: 153947243

Centisome position: 80.45

GC content: 50.56

Gene sequence:

>534_bases
GTGATCGGTATTCTAAATCGTTGGCGACAATTTGGCAGACGTTATTTCTGGCCGCATCTCCTGTTGGGGATGGTCGCGGC
GAGTCTTGGTGTGCCATCAAATCTGTCTGGCGTTCCAGACCATGCGGCATTAGCGAACACATCATCCAGCCAAAGTCGTC
AGAATCATGGTACGACAAACTTCAACAGTTTGGCACTGTTGCATGACATACACCGTCGCCCCTCATTCAGTGTAGATTAC
TGGCAACAGCATGCCCTGCGCACGGTCATCCGTCACCTCTCTTTTGCTCTGGCACCACAAGCGGCATATGCACGCGTACA
AGAAGTCGCCGAAACAGAACGGGTTGCTCCATCAAAAATTCAGCAACTCGCGTTACTGGATACGCTAAATGCACTACTGA
CGCATGAATTTAAGCCACCGGCCATTATTCGCTATACAGAACAGGTTGAACGGCCTGTTCTGTCGCCATATAAACCTGGG
CTCTGGCTTGCTCAAGTACAAGGTATTCGTGCCGGTCCTGCCAACTTAAGCTAA

Upstream 100 bases:

>100_bases
TAGCGGTCCGTTTTCTGCTGCAACCGCATCATCGAACAGAACATCTAATAATTGTGGGCGGTTTTCACGCATTGACAAGG
CTCCGGCGGATTTTAAACTC

Downstream 100 bases:

>100_bases
TTATTCTCTTGGTTTATCCCAATTTTATACAACCTTTGGCCGCCGGTTTGGTGGTCTTGTAAGAGATATTAAGAATCATG
CTAATTAAATTATTAACCAA

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDY
WQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPG
LWLAQVQGIRAGPANLS

Sequences:

>Translated_177_residues
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDY
WQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPG
LWLAQVQGIRAGPANLS
>Mature_177_residues
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDY
WQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPG
LWLAQVQGIRAGPANLS

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family

Homologues:

Organism=Escherichia coli, GI87081686, Length=182, Percent_Identity=50, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECM_YERP3 (A7FM58)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402336.1
- STRING:   A7FM58
- GeneID:   5384702
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3379
- eggNOG:   NOG07544
- HOGENOM:   HBG416690
- OMA:   FAMAPQA
- ProtClustDB:   PRK02943
- BioCyc:   YPSE349747:YPSIP31758_3379-MONOMER
- GO:   GO:0005829
- HAMAP:   MF_01332
- InterPro:   IPR009502
- PIRSF:   PIRSF004572
- ProDom:   PD089227

Pfam domain/function: PF06558 SecM

EC number: NA

Molecular weight: Translated: 19805; Mature: 19805

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCC
FNSLALLHDIHRRPSFSVDYWQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
QQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCC
FNSLALLHDIHRRPSFSVDYWQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
QQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA